2445205-24-1
2445205-24-1
Chemical Structure
CDK4/6-IN-12
- CAS No.: 2445205-24-1
- Formula:C12H10N6
- Molecular Weight:238.25
IUPAC Name: 2-amino-5,8-dimethylimidazo[1',2':1,6]pyrido[2,3-d]pyrimidine-6-carbonitrile
InChIKey: GLDQROMTPTWBPL-UHFFFAOYSA-N
SMILES: CC1=CN2C3=NC(N)=NC=C3C(C)=C(C2=N1)C#N
Biological Activity: CDK4/6-IN-12 is a potent cyclin-dependent kinase 4/6 (CDK4/6) inhibitor. CDK4/6-IN-12 has enzymatic inhibitory activity for CDK4 and CDK6 with IC50 of 592.3 nM and 3090 nM, respectively. CDK4/6-IN-12 can be used for the research of cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CDK4/6-IN-12 | 99.76% | CDK4/6-IN-12 is a potent cyclin-dependent kinase 4/6 (CDK4/6) inhibitor. CDK4/6-IN-12 has enzymatic inhibitory activity for CDK4 and CDK6 with IC50 of 592.3 nM and 3090 nM, respectively. CDK4/6-IN-12 can be used for the research of cancer. | ||||||||||||||||||||
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References
Keywords
