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TMPD dihydrochloride 

Cat. No.: HY-W012145 Purity: >98.0%
Handling Instructions

TMPD dihydrochloride, a readily oxidizable compound, is an enzymatically convert redox active substrate molecule. TMPD dihydrochloride is also an electron donor and serves as a reducing cosubstrate for heme peroxidases. TMPD dihydrochloride is also a complex IV substrate.

For research use only. We do not sell to patients.

TMPD dihydrochloride Chemical Structure

TMPD dihydrochloride Chemical Structure

CAS No. : 637-01-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
100 mg USD 50 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

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Based on 1 publication(s) in Google Scholar

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Description

TMPD dihydrochloride, a readily oxidizable compound, is an enzymatically convert redox active substrate molecule. TMPD dihydrochloride is also an electron donor and serves as a reducing cosubstrate for heme peroxidases[1][2]. TMPD dihydrochloride is also a complex IV substrate[3].

In Vitro

TMPD (N,N,N′,N′-tetramethyl-para-phenylene-diamine) is used in cell culture and microbiology to differentiate organisms that exhibit cytochrome c oxidase activity and to distinguish between Gram-negative and Gram-positive pathogenic and non-pathogenic bacteria. The concept of TMPD oxidation by microorganisms is widely used and is known as a successful colorimetric indicator for bacterial oxidases, as the radical cation TMPD+˙, formed by oxidation, shows a characteristic deep blue colour. The electrochemical recognition of the TMPD oxidation by bacterial oxidases can be applied to a variety of pathogens[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

237.17

Formula

C₁₀H₁₈Cl₂N₂

CAS No.

637-01-4

SMILES

CN(C)C1=CC=C(N(C)C)C=C1.[H]Cl.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 16.67 mg/mL (70.29 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.2164 mL 21.0819 mL 42.1638 mL
5 mM 0.8433 mL 4.2164 mL 8.4328 mL
10 mM 0.4216 mL 2.1082 mL 4.2164 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 1.67 mg/mL (7.04 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

TMPDOthersCytochrome-cenzymaticallyconvertredoxactivesubstratecomplex-IVblueelectrondonorInhibitorinhibitorinhibit

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Product Name:
TMPD dihydrochloride
Cat. No.:
HY-W012145
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