Prostaglandin A3
Prostaglandin A3 is a non-enzymatic dehydration product of prostaglandin E3 (PGE3). Prostaglandin A3 showed good affinity for canine EP2 and EP4 receptors with IC50 values of 120 and 20 nM, respectively. The Ki value of Prostaglandin A3 for human PPARγ was 188 μM.
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- CAS. Nr.: 36614-31-0
- Formel: C20H28O4
- Molecular Weight:332.43
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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EP2 120 nM (IC50) |
EP4 20 nM (IC50) |
PPAR-γ 188 μM (Ki) |
Chemical Information
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CAS. Nr. 36614-31-0
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Molecular Weight 332.43
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Formel C20H28O4
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SMILES
O=C1[C@@H]([C@H](C=C1)/C=C/[C@H](C/C=C\CC)O)C/C=C\CCCC(O)=O
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Synonyms
PGA3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Hibbs TA, et al. Molecular cloning and characterization of the canine prostaglandin E receptor EP2 subtype. Prostaglandins Other Lipid Mediat. 1999 May;57(2-3):133-47. [Content Brief]
[2]. Castleberry TA, et al. Molecular cloning and functional characterization of the canine prostaglandin E2 receptor EP4 subtype. Prostaglandins Other Lipid Mediat. 2001 Jul;65(4):167-87. [Content Brief]
[3]. Ferry G, et al. Binding of prostaglandins to human PPARgamma: tool assessment and new natural ligands. Eur J Pharmacol. 2001 Apr 6;417(1-2):77-89. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Prostaglandin A3 Related Classifications
HY-114822 Related Classifications
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