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Cat. No.: HY-157438

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pppApA

pppApA is a nucleotide intermediate. pppApA participates in the enzymatic synthesis of the bacterial signaling nucleotide c-diAMP.

For research use only. We do not sell to patients.

CAS No.: 17730-98-2
Formula: C₂₀H₂₈N₁₀O₁₉P₄
Molecular Weight:836.39

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

pppApA Chemical Structure

CAS No.: 17730-98-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

pppApA is a nucleotide intermediate. pppApA participates in the enzymatic synthesis of the bacterial signaling nucleotide c-diAMP^[1]^[2].

All DNA/RNA Synthesis Isoforms :

In Vitro

Nucleotide intermediates are nucleotide-like intermediate metabolites carrying phosphate groups that lie between precursors and final products in nucleic acid synthesis, energy metabolism, and signaling pathways.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 17730-98-2
Molecular Weight 836.39
Formula C₂₀H₂₈N₁₀O₁₉P₄
SMILES

O[C@H]1[C@@H](O[C@@H]([C@H]1OP(OC[C@H]2O[C@@H](N3C4=NC=NC(N)=C4N=C3)[C@@H]([C@@H]2O)O)(O)=O)COP(OP(OP(O)(O)=O)(O)=O)(O)=O)N5C6=NC=NC(N)=C6N=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (276 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Whiteley AT, et al. Bacterial cGAS-like enzymes synthesize diverse nucleotide signals. Nature. 2019 Mar;567(7747):194-199.

[2]. Gándara C. Role of DisA and c-di-AMP in the DNA damage response of exponentially growing Bacillus subtilis cells (Doctoral dissertation, et al.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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