2-O-α-D-Glucopyranosyl-L-ascorbic Acid

Name: 2-O-α-D-Glucopyranosyl-L-ascorbic Acid
Brand: MedChemExpress
SKU: HY-N6821
Rating: 4.5 (1 reviews)

Cat. No.: HY-N6821 Purity: 99.58%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

2-O-α-D-Glucopyranosyl-L-ascorbic Acid is a glucoside derivative of ascorbic acid, shows anti-cancer activity after enzymatic hydrolysis to ascorbic acid.

For research use only. We do not sell to patients.

2-O-α-D-Glucopyranosyl-L-ascorbic Acid Chemical Structure

CAS No. : 129499-78-1

Size	Price	Stock	Quantity
Solid + Solvent
10 mM * 1 mL in Water ready for reconstitution	USD 28	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	USD 28	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	USD 25	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 35	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 70	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 90	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

2-O-α-D-Glucopyranosyl-L-ascorbic Acid is a glucoside derivative of ascorbic acid, shows anti-cancer activity after enzymatic hydrolysis to ascorbic acid^[1].

Molecular Weight

338.26

Formula

C₁₂H₁₈O₁₁

CAS No.

129499-78-1

Appearance

Solid

Color

White to off-white

SMILES

OC([C@H](O1)[C@H](CO)O)=C(O[C@@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)C1=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

H₂O : 125 mg/mL (369.54 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.9563 mL	14.7815 mL	29.5631 mL
5 mM	0.5913 mL	2.9563 mL	5.9126 mL
10 mM	0.2956 mL	1.4782 mL	2.9563 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 50 mg/mL (147.82 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.58%

Select Batch:

Data Sheet (276 KB) SDS (252 KB)

COA (257 KB) LCMS (96 KB)

Handling Instructions (2659 KB)

References

[1]. Miura K, et al. 2-O-α-D-Glucopyranosyl-l-ascorbic acid as an antitumor agent for infusion therapy. Biochem Biophys Rep. 2017 Apr 22;10:232-236. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	2.9563 mL	14.7815 mL	29.5631 mL	73.9076 mL
	5 mM	0.5913 mL	2.9563 mL	5.9126 mL	14.7815 mL
	10 mM	0.2956 mL	1.4782 mL	2.9563 mL	7.3908 mL
	15 mM	0.1971 mL	0.9854 mL	1.9709 mL	4.9272 mL
	20 mM	0.1478 mL	0.7391 mL	1.4782 mL	3.6954 mL
	25 mM	0.1183 mL	0.5913 mL	1.1825 mL	2.9563 mL
	30 mM	0.0985 mL	0.4927 mL	0.9854 mL	2.4636 mL
	40 mM	0.0739 mL	0.3695 mL	0.7391 mL	1.8477 mL
	50 mM	0.0591 mL	0.2956 mL	0.5913 mL	1.4782 mL
	60 mM	0.0493 mL	0.2464 mL	0.4927 mL	1.2318 mL
	80 mM	0.0370 mL	0.1848 mL	0.3695 mL	0.9238 mL
	100 mM	0.0296 mL	0.1478 mL	0.2956 mL	0.7391 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.