HPK1-IN-25
HPK1-IN-25 (example 94) is a hematopoietic progenitor kinase 1 (HPK1) inhibitor with a enzymatic activity IC50 of 129 nM. HPK1-IN-25 has the potential for cancer research.
For research use only. We do not sell to patients.
- CAS No.: 2403600-50-8
- Formula: C23H25N5O
- Molecular Weight:387.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All MAP4K Isoforms
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Biological Activity
Description
IC50 & Target
[1]|
HPK1 129 nM (IC50) |
Chemical Information
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CAS No. 2403600-50-8
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Molecular Weight 387.48
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Formula C23H25N5O
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SMILES
COC(C=C1)=CC=C1C2=CNC3=NC=C(C4=CN(C5CCN(CC5)C)N=C4)C=C32
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)