1. Peptides
  2. Abz-FRLKGGAPIKGV-EDDNP TFA

Abz-FRLKGGAPIKGV-EDDNP TFA 

Cat. No.: HY-P2296
Handling Instructions

Abz-FRLKGGAPIKGV-EDDNP TFA is a fluorogenic substrate used to measure the enzymatic activities of protease forms, such as papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV). Abz-FRLKGGAPIKGV-EDDNP TFA has the potential for study 2019-nCoV (COVID-19) infection.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Abz-FRLKGGAPIKGV-EDDNP TFA Chemical Structure

Abz-FRLKGGAPIKGV-EDDNP TFA Chemical Structure

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Description

Abz-FRLKGGAPIKGV-EDDNP TFA is a fluorogenic substrate used to measure the enzymatic activities of protease forms, such as papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV). Abz-FRLKGGAPIKGV-EDDNP TFA has the potential for study 2019-nCoV (COVID-19) infection[1].

In Vitro

Abz-FRLKGGAPIKGV-EDDNP TFA has little fluorescent emission because of the fluorescence resonance energy transfer (FRET) between Abz and EDDNP. The apparent kcat and Km values for this fluorogenic substrate at pH 7.4 are 20 min-1 and 77 µM, respectively. The enhanced fluorescence emission upon substrate cleavage is monitored at the excitation and emission wavelengths of 320 and 420 nm, respectively, in the presence or absence of the chemical compounds assayed[1].

Sequence

Abz-{Phe}{Arg}{Leu}{Lys}{Gly}{Gly}{Ala}{Pro}{Ile}{Lys}{Gly}{Val}-EDDNP

Sequence Shortening

Abz-FRLKGGAPIKGV-EDDNP

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Abz-FRLKGGAPIKGV-EDDNPOthersfluorogenicsubstrateenzymaticproteasePapain-likeProtease2PLP2SevereAcuteRespiratorySyndromeCoronavirusSARS-CoV2019-nCoVCOVID-19Inhibitorinhibitorinhibit

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Product name:
Abz-FRLKGGAPIKGV-EDDNP TFA
Cat. No.:
HY-P2296
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