2. Anti-infection
  3. SARS-CoV
  4. Dabcyl-KTSAVLQSGFRKME-Edans TFA

Dabcyl-KTSAVLQSGFRKME-Edans TFA 

Cat. No.: HY-P2295 Purity: 99.69%
COA Handling Instructions

Molarity Calculator

Dabcyl-KTSAVLQSGFRKME-Edans TFA is a fluorogenic peptide. Dabcyl-KTSAVLQSGFRKME-Edans TFA is used as the substrate to measure the enzymatic activities of protease forms. Dabcyl-KTSAVLQSGFRKME-Edans TFA has the potential for study 2019-nCoV (COVID-19) infection.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Dabcyl-KTSAVLQSGFRKME-Edans TFA Chemical Structure

Dabcyl-KTSAVLQSGFRKME-Edans TFA Chemical Structure

Size Price Stock Quantity
5 mg USD 250 In-stock
10 mg USD 400 Get quote
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Dabcyl-KTSAVLQSGFRKME-Edans TFA Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Dabcyl-KTSAVLQSGFRKME-Edans TFA

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Dabcyl-KTSAVLQSGFRKME-Edans TFA is a fluorogenic peptide. Dabcyl-KTSAVLQSGFRKME-Edans TFA is used as the substrate to measure the enzymatic activities of protease forms. Dabcyl-KTSAVLQSGFRKME-Edans TFA has the potential for study 2019-nCoV (COVID-19) infection[1][2][3].

In Vitro

Recombinant 3CLpro is expressed in Pichia pastoris GS115 as a 42 kDa protein that displays a Km of 15 μM with Dabcyl-KTSAVLQSGFRKME-Edans TFA as substrate[1].
The Dabcyl-KTSAVLQSGFRKME-Edans TFA fluorogenic peptide is used as the substrate and the enhanced fluorescence due to cleavage of this substrate catalyzed by the protease is monitored at 538 nm with an excitation wavelength of 355 nm using a fluorescence plate reader[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Dabcyl-KTSAVLQSGFRKME-Edans TFA Related Antibodies
Molecular Weight

2195.44

Formula

C97H142F3N25O26S2
Appearance

Solid

Color

Pink to red

Sequence

Dabcyl-Lys-Thr-Ser-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg-Lys-Met-Glu-Edans
Sequence Shortening

Dabcyl-KTSAVLQSGFRKME-Edans
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (45.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 6.67 mg/mL (3.04 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.4555 mL 2.2774 mL 4.5549 mL
5 mM 0.0911 mL 0.4555 mL 0.9110 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.69%

COA (243 KB) LCMS (103 KB) Elemental Analysis Report (101 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 0.4555 mL 2.2774 mL 4.5549 mL 11.3872 mL
DMSO 5 mM 0.0911 mL 0.4555 mL 0.9110 mL 2.2774 mL
10 mM 0.0455 mL 0.2277 mL 0.4555 mL 1.1387 mL
15 mM 0.0304 mL 0.1518 mL 0.3037 mL 0.7591 mL
20 mM 0.0228 mL 0.1139 mL 0.2277 mL 0.5694 mL
25 mM 0.0182 mL 0.0911 mL 0.1822 mL 0.4555 mL
30 mM 0.0152 mL 0.0759 mL 0.1518 mL 0.3796 mL
40 mM 0.0114 mL 0.0569 mL 0.1139 mL 0.2847 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dabcyl-KTSAVLQSGFRKME-Edans TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dabcyl-KTSAVLQSGFRKME-EdansSARS-CoVSARS coronavirusfluorogenicpeptidesubstrateenzymaticactivitiesprotease2019-nCoVCOVID-19infectionInhibitorinhibitorinhibit

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