1. Peptides
  2. Dabcyl-KTSAVLQSGFRKME-Edans TFA

Dabcyl-KTSAVLQSGFRKME-Edans TFA 

Cat. No.: HY-P2295
Handling Instructions

Dabcyl-KTSAVLQSGFRKME-Edans TFA is a fluorogenic peptide. Dabcyl-KTSAVLQSGFRKME-Edans TFA is used as the substrate to measure the enzymatic activities of protease forms. Dabcyl-KTSAVLQSGFRKME-Edans TFA has the potential for study 2019-nCoV (COVID-19) infection.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Dabcyl-KTSAVLQSGFRKME-Edans TFA Chemical Structure

Dabcyl-KTSAVLQSGFRKME-Edans TFA Chemical Structure

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Description

Dabcyl-KTSAVLQSGFRKME-Edans TFA is a fluorogenic peptide. Dabcyl-KTSAVLQSGFRKME-Edans TFA is used as the substrate to measure the enzymatic activities of protease forms. Dabcyl-KTSAVLQSGFRKME-Edans TFA has the potential for study 2019-nCoV (COVID-19) infection[1][2][3].

In Vitro

Recombinant 3CLpro is expressed in Pichia pastoris GS115 as a 42 kDa protein that displays a Km of 15 μM with Dabcyl-KTSAVLQSGFRKME-Edans TFA as substrate[1].
The Dabcyl-KTSAVLQSGFRKME-Edans TFA fluorogenic peptide is used as the substrate and the enhanced fluorescence due to cleavage of this substrate catalyzed by the protease is monitored at 538 nm with an excitation wavelength of 355 nm using a fluorescence plate reader[1].

Sequence

Dabcyl-Lys-Thr-Ser-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg-Lys-Met-Glu-Edans

Sequence Shortening

Dabcyl-KTSAVLQSGFRKME-Edans

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Dabcyl-KTSAVLQSGFRKME-EdansOthersfluorogenicpeptidesubstrateenzymaticactivitiesprotease2019-nCoVCOVID-19infectionInhibitorinhibitorinhibit

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Product name:
Dabcyl-KTSAVLQSGFRKME-Edans TFA
Cat. No.:
HY-P2295
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