AcrB-IN-4
Efflux pump-IN-4 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. Efflux pump-IN-4 inhibits Nile Red (a known substrate of AcrB) efflux. Efflux pump-IN-4 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2890177-95-2
- 分子式: C29H34N2O4S
- 分子量:506.66
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
製品説明
体外実験
Efflux pump-IN-4 (compound G11) (8-128 μg/mL) shows outstanding antibacterial synergism with at least one of the antibiotics (ERY, LEV and MIN). Efflux pump-IN-4 show antibacterial synergism with MIN, and reduces the MIC value of LEV by 4-fold at 8 μg/mL[1].
Efflux pump-IN-4 (50 μM, 100 μM) shows strong inhibitory activity at the lowest concentration of 50 μM, to inhibit Nile Red efflux[1].
Efflux pump-IN-4 (4-256 μg/mL) does not cause hemolysis of mice red blood cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2890177-95-2
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分子量 506.66
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分子式 C29H34N2O4S
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SMILES
O=C(N1CCOCC1)C2=CC3=C(C4=C2CCC(C)(C)O4)C=CC=C3OCCCSC5=CC=C(C=C5)N
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
AcrB-IN-4 関連分類
HY-149812 関連分類
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