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Cat. No.: HY-B0132B

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Norfloxacin (nicotinate)

(Synonyms: MK-0366 (nicotinate))

4 Cited Publications

Customer Review

Based on 4 publication(s) in Google Scholar

Norfloxacin nicotinate (MK-0366 nicotinate) is a fluoroquinolones antibiotic, an adduct of Norfloxacin (NOR) and nicotinic acid. Norfloxacin nicotinate has been widely used for replacing NOR in animal husbandry and fishery industry. Norfloxacin nicotinate can induce innate immune response at a high concentration.

For research use only. We do not sell to patients.

CAS No.: 118803-81-9
Formula: C₂₂H₂₃FN₄O₅
Molecular Weight:442.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Norfloxacin (nicotinate) Chemical Structure

CAS No.: 118803-81-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Publications (4)
Purity & Documentation
References
Calculators
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Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target

Quinolone

All Antibiotic Isoforms :

In Vivo

Norfloxacin nicotinate (5 and/or 25 mg/L) significantly induces antioxidant enzymes activities and the mRNA levels of genes related to antioxidant enzymes and innate immune system in zebrafish larvae^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 118803-81-9
Molecular Weight 442.44
Formula C₂₂H₂₃FN₄O₅
SMILES

O=C(C1=CN(CC)C2=C(C=C(F)C(N3CCNCC3)=C2)C1=O)O.O=C(C4=CC=CN=C4)O
Synonyms

MK-0366 (nicotinate)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (4)

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Theranostics

Antibiotic Azithromycin inhibits brown/beige fat functionality and promotes obesity in human and rodents. [Abstract]

2022 Jan 1;12(3):1187-1203. PMID: 35154482
Water Res

Quantifying community-wide antibiotic usage via urban water fingerprinting: Focus on contrasting resource settings in South Africa. [Abstract]

2023 Jul 15:240:120110. PMID: 37247434
Food Chem X

Machine learning prioritization of antibiotic residues in aquatic foods reveals exposure-driven genotoxic risk mediated by BCL2. [Abstract]

2026 Feb 8:34:103646. PMID: 41756597
J Environ Qual

Competitive and synergistic sorption of norfloxacin and bisphenol A onto two different microplastics. [Abstract]

2025 Oct 21. PMID: 41117009

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Liang X, et al. Effects of norfloxacin nicotinate on the early life stage of zebrafish (Danio rerio): Developmental toxicity, oxidative stress and immunotoxicity. Fish Shellfish Immunol. 2020 Jan;96:262-269. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Norfloxacin (nicotinate)

4 Cited Publications

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Biological Activity
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Publications (4)
Purity & Documentation
References

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Norfloxacin (nicotinate)

Publications Citing Use of MedChemExpress (MCE) Norfloxacin (nicotinate)

All Antibiotic Isoforms

Biological Activity

Chemical Information

Publications (4)

Purity & Documentation

References

Calculators

Help & FAQs

Norfloxacin (nicotinate) Related Classifications

HY-B0132B Related Classifications