Search Result
Results for "
Nitra
" in MedChemExpress (MCE) Product Catalog:
7
Biochemical Assay Reagents
8
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-B1006
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- HY-P2996
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Others
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Others
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NAD(P)H-Nitrate reductase is isolated from Aspergillus niger that catalyses the reduction of nitrate to nitrite via a two-electron transfer. In plants, the electron donor for Nitrate reductase is NADPH is NADH:Nitrate reductase and a bispecific NAD(P)H: Nitrate reductase .
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- HY-B0454A
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- HY-B2223
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- HY-B0453
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- HY-B1444
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Bacterial
Fungal
Antibiotic
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Infection
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Isoconazole nitrate is a broad-spectrum antimicrobial agent with a highly effective antimycotic and gram-positive antibacterial activity, exhibiting a rapid rate of absorption and low systemic exposure potential .
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- HY-B1324
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Ro 13-8996
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Fungal
Cytochrome P450
Antibiotic
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Infection
Cancer
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Oxiconazole (Ro 13-8996) nitrate is a broad spectrum anti-fungal agent which can inhibit the growth of Candida, Aspergillus and Trichophyton. Oxiconazole nitrate is also a highly efficacious activator of CYP3A4 transactivation, which could be antagonized by Rifampicin (HY-B0272) in a competitive manner. Oxiconazole nitrate exhibits inhibitory effect against colorectal cancer (CRC) via peroxiredoxin-2 (PRDX2)-mediated autophagy arrest .
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- HY-B0736A
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FI7056
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Fungal
Autophagy
Apoptosis
p38 MAPK
Microtubule/Tubulin
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Infection
Cancer
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Sertaconazole nitrate (FI7056) is a broad-spectrum topical antifungal agent, exhibits anti-inflammatory activity via activation of a p38-COX-2-PGE2 pathway. Sertaconazole nitrate is also a microtubule inhibitor, shows antiproliferative effect, induces apoptosis and autophagy, and can also inhibit the migration of cells .
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- HY-B0359
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REC 15-1476
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Fungal
Antibiotic
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Infection
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Fenticonazole Nitrate is an antifungal imidazole ring derivative. Fenticonazole Nitrate operates via hindering ergosterol integration, and sequentially destructing the cytoplasmatic outer membrane. Fenticonazole Nitrate is effective against Gram-positive bacteria, mycoses, and vaginal candidiasis .
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- HY-B0293
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RS 35887
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Fungal
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Infection
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Butoconazole nitrate (RS 35887), an imidazole antifungal agent, is active against Candida spp. and effective against vaginal infections due to Candida albicans. Butoconazole nitrate is presumed to function as other imidazole derivatives via inhibition of steroid synthesis .
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- HY-112076A
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Methylatropine Nitrate; Atropine methyl Nitrate
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mAChR
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Neurological Disease
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Atropine methyl bromide, a muscarinic receptor (mAChR) antagonist, is a quaternary ammonium salt of atropine and a mydriatic for dilation of the pupil during ophthalmic examination. It is introduced for relieving pyloric spasm in infants for its highly polar nature. It penetrates less readily into the central nervous system than atropine .
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- HY-111326A
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- HY-W127702
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Methscopolamine Nitrate
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Biochemical Assay Reagents
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Others
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Scopolamine methyl nitrate is an organic compound commonly used in neuroscience research and pharmacology research. It can be used to study the role and structure of acetylcholine receptors, and is widely used in drug development and research in related fields. In addition, this compound is also used as a substrate or catalyst in certain biochemical reactions.
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- HY-U00279
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DNA/RNA Synthesis
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Cancer
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Nitracrine inhibits RNA synthesis and covalently, reversibly binds to DNA but also forms covalent adducts with DNA in vivo. Nitracrine, a 1-nitroacridine derivative, is a potent hypoxia-selective agent in vitro and antitumor agent. Nitracrine has cytotoxicity towards most cells .
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- HY-W011393
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- HY-N4238
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13-Methylpalmatine Nitrate
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Bcl-2 Family
Caspase
PARP
p38 MAPK
Parasite
Autophagy
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Infection
Cancer
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Dehydrocorydaline nitrate (13-Methylpalmatine nitrate) is an alkaloid. Dehydrocorydaline regulates protein expression of Bax, Bcl-2; activates caspase-7, caspase-8, and inactivates PARP . Dehydrocorydaline nitrate elevates p38 MAPK activation. Anti-inflammatory and anti-cancer activities. . Dehydrocorydaline nitrate shows strong anti-malarial effects (IC50 =38 nM), and low cytotoxicity (cell viability > 90%) using P. falciparum 3D7 strain .
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- HY-128545
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Nitrazine paper; Phenaphthazine
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Biochemical Assay Reagents
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Others
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Nitrazine yellow (Nitrazine paper; Phenaphthazine) is a pH indicator. The color of Nitrazine yellow changes from yellow to blue in the pH range from 6.0 to 7.0. Nitrazine yellow is a kind of biological materials or organic compounds that are widely used in life science research .
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- HY-168376
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9(10)-Nitrated oleic acid
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PPAR
ERK
Akt
NO Synthase
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Metabolic Disease
Inflammation/Immunology
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9 (10)-Nitrooleate (9(10)-Nitrated oleic acid) is an endogenous lipid signaling mediator with vasoprotective effects. 9 (10)-Nitrooleate enhances enzymatic activity and improves nitric oxide bioavailability by inducing phosphorylation of Akt and ERK1/2, regulating the multi-site phosphorylation status of eNOS and optimizing its interaction with Hsp90. 9 (10)-Nitrooleate also activates PPARα, PPARδ and PPARγ receptors, thereby regulating adipogenesis, glucose uptake and inflammation-related gene expression, and exhibits immunosuppressive effects by inhibiting neutrophil migration and cytokine secretion. 9 (10)-Nitrooleate is widely used in studies of sepsis and related inflammatory diseases .
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- HY-116548
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Dopamine Receptor
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Neurological Disease
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Nitracaine is a structural analog of Dimethocaine (HY-121870), a local anesthetic that inhibits dopamine reuptake through the dopamine transporter .
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- HY-106542A
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Fungal
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Infection
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Eberconazole nitrate is a dichlorinated imidazole derivative with antifungal activity. Eberconazole nitrate is more effective than Clotrimazole (HY-10882), Ketoconazole (HY-B0105), and Miconazole (HY-B0454). Eberconazole nitrate has potential for the study of dermatophytosis .
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- HY-W127677
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N,N,N-Triethylethanaminium Nitrate
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Biochemical Assay Reagents
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Others
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Tetraethylammonium nitrate is a quaternary ammonium salt commonly used as an electrolyte in various chemical reactions, especially in electrochemistry and battery technology. Tetraethylammonium nitrate has unique chemical properties that make it an important ingredient in a variety of industrial processes, including the production of advanced materials and electronic components.
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- HY-W401947
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- HY-P2996A
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Drug Isomer
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Others
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Nitrate Reductase, Arabidopsis thaliana is the isomer of NAD(P)H-Nitrate reductase (HY-P2996). NAD(P)H-Nitrate reductase is isolated from Aspergillus niger that catalyses the reduction of nitrate to nitrite via a two-electron transfer. In plants，the electron donor for Nitrate reductase is NADPH is NADH:Nitrate reductase and a bispecific NAD(P)H: Nitrate reductase .
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- HY-P2996B
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Others
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Others
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Nitrate Reductase (NAD[P]H), Pichia pastoris (recombinant) is a simplified version of nitrate reductase S-NaR1 expressed and purified by Pichia pastoris. Nitrate Reductase (NAD[P]H), Pichia Pastoris (recombinant) contains sites binding molybdenum-molybdenopyridine (Mo-MPT) and nitrate reduction active sites and only contains two domains instead of the five domains of the complete NaR. This simplified form of nitrate reductase was expressed in high density in P. pastoris and purified to homogeneity in one step by fixed metal affinity chromatography (IMAC). Nitrate Reductase (NAD[P]H), Pichia Pastoris (recombinant) can be used in the development of biosensors and environmental monitoring .
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![Nitrate Reductase (NAD[P]H), Pichia Pastoris (recombinant)](//file.medchemexpress.com/product_pic/hy-p2996b.gif)
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- HY-W749797
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GABA Receptor
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Neurological Disease
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Nitrazolam is a benzodiazepine compound, that may exhibit CNS depressant properties as traditional benzodiazepines, including sedation, hypnosis, anxiolysis, and anticonvulsant effects, by acting on GABA receptors .
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- HY-B1444R
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Reference Standards
Bacterial
Fungal
Antibiotic
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Infection
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Isoconazole (nitrate) (Standard) is the analytical standard of Isoconazole (nitrate). This product is intended for research and analytical applications. Isoconazole nitrate is a broad-spectrum antimicrobial agent with a highly effective antimycotic and gram-positive antibacterial activity, exhibiting a rapid rate of absorption and low systemic exposure potential .
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- HY-W705651
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- HY-W740026
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- HY-179182
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- HY-179182A
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- HY-105747A
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N-(3-Phenoxypropyl)guanidine Nitrate; (3-Phenoxypropyl)guanidine Nitrate
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Endogenous Metabolite
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Infection
Neurological Disease
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Guanoxyfen (N-(3-Phenoxypropyl)guanidine) nitrate is a compound that exhibits potent inhibitory activity against the serine protease enzyme TMPRSS2, which plays a crucial role in the infectivity of coronaviruses. Guanoxyfen nitrate is also an effective inhibitor of vasoconstrictor responses to sympathetic nerve stimulation.
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- HY-B0556B
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Tetryzoline Nitrate
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Adrenergic Receptor
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Cardiovascular Disease
Metabolic Disease
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Tetrahydrozoline (Tetryzoline) nitrate , a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline is widely used for the research of nasal congestion and conjunctival congestion .
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- HY-B0454S1
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- HY-12784S1
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Chlorguanide triazine-d6 Nitrate
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Isotope-Labeled Compounds
Antifolate
DNA/RNA Synthesis
STAT
Parasite
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Infection
Cancer
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Cycloguanil-d6 (Chlorguanide triazine-d6) nitrate is the deuterium labeled Cycloguanil nitrate. Cycloguanil nitrate is a dihydrofolate reductase (DHFR) inhibitor with an IC50 of 10.8 μM against human DHFR. Cycloguanil nitrate blocks the folate metabolic pathway, thereby affecting nucleotide synthesis and interfering with DNA replication. Cycloguanil nitrate inhibits DHFR in Plasmodium and is thus used in malaria research. Cycloguanil nitrate also potently inhibits DHFR in human cancer cells and blocks the transcriptional activity of STAT3, thereby exhibiting anticancer activity .
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- HY-111326AR
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Naphthazoline Nitrate (Standard)
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Reference Standards
Adrenergic Receptor
TNF Receptor
Interleukin Related
VEGFR
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Cardiovascular Disease
Inflammation/Immunology
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Naphazoline (nitrate) (Standard) is the analytical standard of Naphazoline (nitrate). This product is intended for research and analytical applications. Naphazoline (Naphthazoline) nitrate is an α-adrenergic receptor agonist. Naphazoline nitrate reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline nitrate reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. Naphazoline nitrate can be used for non-bacterial conjunctivitis research .
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- HY-B2223R
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- HY-B0454AR
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R18134 Nitrate (Standard)
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Reference Standards
Fungal
Bacterial
Antibiotic
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Infection
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Miconazole (nitrate) (Standard) is the analytical standard of Miconazole (nitrate). This product is intended for research and analytical applications. Miconazole nitrate (R18134 nitrate) is an imidazole antifungal agent. Miconazole nitrate also has antibacterial effects .
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- HY-B0454AS
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R18134-d5 Nitrate (2,4-Dichlorobenzyloxy-d5)
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Fungal
Bacterial
Antibiotic
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Infection
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Miconazole-d5 (nitrate) (2,4-Dichlorobenzyloxy-d5) is the deuterium labeled Miconazole nitrate. Miconazole nitrate (R18134 nitrate) is an imidazole antifungal agent. Miconazole nitrate also has antibacterial effects .
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- HY-U00279B
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DNA/RNA Synthesis
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Cancer
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Nitracrine hydrochloride is a platinum-based antineoplastic drug with selective toxicity to hypoxic cells. Nitracrine hydrochloride exhibits significant cytotoxicity against the Chinese hamster ovary cell line AA8 under hypoxic conditions. Nitracrine hydrochloride exerts its effect by binding to the insertion of DNA and forming covalent adducts. The cytotoxicity of Nitracrine hydrochloride under hypoxic conditions is related to its reductive metabolism to form alkylated substances. At the same time, it may enhance the reactivity to DNA through the insertion of DNA, thereby improving the efficacy. Nitracrine hydrochloride can also inhibit RNA synthesis, contributing to its anti-tumor effect .
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- HY-N7507A
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Wnt
β-catenin
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Cancer
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Sempervirine is an alkaloid derived from Gelsemium elegans Benth.. Sempervirine inhibits the proliferation of hepatocellular carcinoma (HCC) cells and induces apoptosis by regulating Wnt/β-catenin pathway .
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- HY-B0847S1
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Fungal
Reactive Oxygen Species (ROS)
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Infection
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Propiconazole-d3 (nitrate) is the deuterium labeled Propiconazole nitrate. Propiconazole is a broad-spectrum triazole fungicide that inhibits the conversion of lanosterol to ergosterol, leading to fungal cell membrane disruption. Propiconazole inhibits S. cerevisiae, but not rat liver, microsomal cytochrome P450 (IC50s=0.04 and >200 µM, respectively). Propiconazole inhibits the growth of T. deformans and R. stolonifer (ED50s=0.073 and 4.6 µg/mL, respectively). Propiconazole increases production of reactive oxygen species (ROS).
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- HY-U00279A
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DNA/RNA Synthesis
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Cancer
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Nitracrine dihydrochloride hydrate inhibits RNA synthesis and covalently, reversibly binds to DNA but also forms covalent adducts with DNA in vivo. Nitracrine dihydrochloride hydrate, a 1-nitroacridine derivative, is a potent hypoxia-selective agent in vitro and antitumor agent. Nitracrine dihydrochloride hydrate has cytotoxicity towards most cells .
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- HY-B1006R
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Reference Standards
mAChR
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Neurological Disease
Cancer
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Pilocarpine (nitrate) (Standard) is the analytical standard of Pilocarpine (nitrate). This product is intended for research and analytical applications. Pilocarpine nitrate is a potent M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist.
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- HY-W700028
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- HY-106542AR
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Reference Standards
Fungal
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Infection
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Eberconazole nitrate (Standard) is the analytical standard of Eberconazole nitrate. This product is intended for research and analytical applications. Eberconazole nitrate is a dichlorinated imidazole derivative with antifungal activity. Eberconazole nitrate is more effective than Clotrimazole (HY-10882), Ketoconazole (HY-B0105), and Miconazole (HY-B0454). Eberconazole nitrate has potential for the study of dermatophytosis .
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- HY-150349
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- HY-B0453R
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Reference Standards
Fungal
Bacterial
Antibiotic
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Infection
Cancer
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Econazole (nitrate) (Standard) is the analytical standard of Econazole (nitrate). This product is intended for research and analytical applications. Econazole nitrate is an imidazole class antifungal medication . Econazole nitrate also has antibacterial activity .
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- HY-101559S
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Isotope-Labeled Compounds
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Inflammation/Immunology
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10-Nitrooleate-d17 (nitrate) is the deuterium labeled 10-Nitrooleic acid nitrate. 10-Nitrooleic acid (CXA-10) nitrate, a nitro fatty acid, has potential effects in disease states in which oxidative stress, inflammation, fibrosis, and/or direct tissue toxicity play significant roles .
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- HY-130096
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ADC Linker
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Cancer
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Ald-Ph-amido-C2-nitrate (Example XXIVb) is a thiazolidine derivative, used as a noncleavable ADC linker .
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- HY-100295
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- HY-B0736AR
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FI7056 (Standard)
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Reference Standards
Fungal
Autophagy
Apoptosis
p38 MAPK
Microtubule/Tubulin
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Infection
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Sertaconazole (nitrate) (Standard) is the analytical standard of Sertaconazole (nitrate). This product is intended for research and analytical applications. Sertaconazole nitrate (FI7056) is a broad-spectrum topical antifungal agent, exhibits anti-inflammatory activity via activation of a p38-COX-2-PGE2 pathway. Sertaconazole nitrate is also a microtubule inhibitor, shows antiproliferative effect, induces apoptosis and autophagy, and can also inhibit the migration of cells .
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- HY-B1324R
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Ro 13-8996 (Standard)
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Reference Standards
Fungal
Cytochrome P450
Antibiotic
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Infection
Cancer
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Oxiconazole nitrate (Standard) is the analytical standard of Oxiconazole nitrate. This product is intended for research and analytical applications. Oxiconazole (Ro 13-8996) nitrate is a broad spectrum anti-fungal agent which can inhibit the growth of Candida, Aspergillus and Trichophyton. Oxiconazole nitrate is also a highly efficacious activator of CYP3A4 transactivation, which could be antagonized by Rifampicin (HY-B0272) in a competitive manner. Oxiconazole nitrate exhibits inhibitory effect against colorectal cancer (CRC) via peroxiredoxin-2 (PRDX2)-mediated autophagy arrest .
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- HY-B0293R
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RS 35887 (Standard)
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Reference Standards
Fungal
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Infection
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Butoconazole (nitrate) (Standard) is the analytical standard of Butoconazole (nitrate). This product is intended for research and analytical applications. Butoconazole nitrate (RS 35887), an imidazole antifungal agent, is active against Candida spp. and effective against vaginal infections due to Candida albicans. Butoconazole nitrate is presumed to function as other imidazole derivatives via inhibition of steroid synthesis .
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- HY-B0359R
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REC 15-1476 (Standard)
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Reference Standards
Fungal
Antibiotic
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Infection
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Fenticonazole (Nitrate) (Standard) is the analytical standard of Fenticonazole (Nitrate). This product is intended for research and analytical applications. Fenticonazole Nitrate is an antifungal imidazole ring derivative. Fenticonazole Nitrate operates via hindering ergosterol integration, and sequentially destructing the cytoplasmatic outer membrane. Fenticonazole Nitrate is effective against Gram-positive bacteria, mycoses, and vaginal candidiasis .
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- HY-179182B
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- HY-W714201
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Herbicide
Parasite
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Infection
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Nitralin is a dinitroaniline herbicide. Nitralin exhibits inhibitory activity against Cryptosporidium parvum, with a IC50 of 4.5 µM .
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- HY-182424
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Parasite
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Infection
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Nitramisole is a nitrobenzene-heterocycle conjugate and microfilaricide. Nitramisole kills microfilariae of Brugia malayi, Dipetalonema viteae and Litomosoides carinii. Nitramisole can be used for the research of filariasis (Brugia malayi, Dipetalonema viteae, Litomosoides carinii infections) .
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- HY-N2079A
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- HY-108291
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Others
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Cardiovascular Disease
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Propatyl nitrate is a coronary vasodilator. Propatyl nitrate is also a nitric oxide donor. Propatyl nitrate can be used in research on cardiovascular and cerebrovascular diseases such as acute angina attacks .
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- HY-P2996E
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- HY-106483
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TVX 2706
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Phosphodiesterase (PDE)
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Neurological Disease
Inflammation/Immunology
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Nitraquazone (TVX 2706) is an anti-inflammatory and analgesic agent, belonging to the derivatives of Phenylbutazone (HY-B0230). Nitraquazone inhibits phosphodiesterase and enhances the elevation of intracellular cyclic adenosine monophosphate levels. Nitraquazone can be used in research related to anti-inflammation and analgesia .
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- HY-P2996D
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- HY-P2996C
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Biochemical Assay Reagents
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Metabolic Disease
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Nitrate Reductase (cytochrome), Escherichia coli (EC 1.9.6.1) is an enzyme of ferrocytochrome: nitrate oxidoreductase. Nitrate Reductase (cytochrome), Escherichia coli (EC 1.9.6.1) catalyzes the following chemical reaction: ferrocytochrome, H+, and nitrate to produce ferrocytochrome and nitrite.
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| Cat. No. |
Product Name |
Type |
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- HY-W127702
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Methscopolamine Nitrate
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Biochemical Assay Reagents
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Scopolamine methyl nitrate is an organic compound commonly used in neuroscience research and pharmacology research. It can be used to study the role and structure of acetylcholine receptors, and is widely used in drug development and research in related fields. In addition, this compound is also used as a substrate or catalyst in certain biochemical reactions.
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- HY-128545
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Nitrazine paper; Phenaphthazine
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Biochemical Assay Reagents
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Nitrazine yellow (Nitrazine paper; Phenaphthazine) is a pH indicator. The color of Nitrazine yellow changes from yellow to blue in the pH range from 6.0 to 7.0. Nitrazine yellow is a kind of biological materials or organic compounds that are widely used in life science research .
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- HY-W127677
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N,N,N-Triethylethanaminium Nitrate
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Biochemical Assay Reagents
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Tetraethylammonium nitrate is a quaternary ammonium salt commonly used as an electrolyte in various chemical reactions, especially in electrochemistry and battery technology. Tetraethylammonium nitrate has unique chemical properties that make it an important ingredient in a variety of industrial processes, including the production of advanced materials and electronic components.
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- HY-W401947
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Biochemical Assay Reagents
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Isosorbide 2-Nitrate is a nitrate that acts as a vasodilator. Isosorbide 2-Nitrate acts by releasing nitric oxide, which subsequently activates guanylate cyclase in smooth muscle cells .
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- HY-179182
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- HY-179182A
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Biochemical Assay Reagents
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Hoagland Nutrient Solution (Phosphorus-Free, Calcium nitrate-Free) is a nutrient solution for hydroponics of plants .
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- HY-179182B
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Biochemical Assay Reagents
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Hoagland Nutrient Solution (Phosphorus deficiency, Calcium nitrate-Free) is a nutrient solution for hydroponics of plants .
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Optimized version of product available:
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| Cat. No. |
Product Name |
Chemical Structure |
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- HY-W705651
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Econazole nitrate-d6 is deuterium labeled Econazole (nitrate). Econazole nitrate is an imidazole class antifungal medication . Econazole nitrate also has antibacterial activity .
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- HY-W740026
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7-Amino nitrazepam-d5 is the deuterium labeled 7-Amino Nitrazepam (HY-W740025).
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- HY-B0454S1
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Miconazole-d5 (nitrate) is the deuterium labeled Miconazole. Miconazole (R18134) is an imidazole antifungal agent. Miconazole also has antibacterial effects .
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- HY-12784S1
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Cycloguanil-d6 (Chlorguanide triazine-d6) nitrate is the deuterium labeled Cycloguanil nitrate. Cycloguanil nitrate is a dihydrofolate reductase (DHFR) inhibitor with an IC50 of 10.8 μM against human DHFR. Cycloguanil nitrate blocks the folate metabolic pathway, thereby affecting nucleotide synthesis and interfering with DNA replication. Cycloguanil nitrate inhibits DHFR in Plasmodium and is thus used in malaria research. Cycloguanil nitrate also potently inhibits DHFR in human cancer cells and blocks the transcriptional activity of STAT3, thereby exhibiting anticancer activity .
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- HY-B0454AS
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Miconazole-d5 (nitrate) (2,4-Dichlorobenzyloxy-d5) is the deuterium labeled Miconazole nitrate. Miconazole nitrate (R18134 nitrate) is an imidazole antifungal agent. Miconazole nitrate also has antibacterial effects .
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- HY-B0847S1
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Propiconazole-d3 (nitrate) is the deuterium labeled Propiconazole nitrate. Propiconazole is a broad-spectrum triazole fungicide that inhibits the conversion of lanosterol to ergosterol, leading to fungal cell membrane disruption. Propiconazole inhibits S. cerevisiae, but not rat liver, microsomal cytochrome P450 (IC50s=0.04 and >200 µM, respectively). Propiconazole inhibits the growth of T. deformans and R. stolonifer (ED50s=0.073 and 4.6 µg/mL, respectively). Propiconazole increases production of reactive oxygen species (ROS).
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- HY-W700028
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rac Butoconazole-d5 Nitrate is the deuterium labeled rac Butoconazole Nitrate.
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- HY-101559S
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10-Nitrooleate-d17 (nitrate) is the deuterium labeled 10-Nitrooleic acid nitrate. 10-Nitrooleic acid (CXA-10) nitrate, a nitro fatty acid, has potential effects in disease states in which oxidative stress, inflammation, fibrosis, and/or direct tissue toxicity play significant roles .
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