1. Anti-infection
  2. Fungal
    Antibiotic
  3. Fenticonazole Nitrate

Fenticonazole Nitrate (Synonyms: REC 15-1476)

Cat. No.: HY-B0359 Purity: 99.44%
Handling Instructions

Fenticonazole Nitrate is an antifungal imidazole ring derivative. Fenticonazole Nitrate operates via hindering ergosterol integration, and sequentially destructing the cytoplasmatic outer membrane. Fenticonazole Nitrate is effective against Gram-positive bacteria, mycoses, and vaginal candidiasis.

For research use only. We do not sell to patients.

Fenticonazole Nitrate Chemical Structure

Fenticonazole Nitrate Chemical Structure

CAS No. : 73151-29-8

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
Solution
10 mM * 1 mL in DMSO USD 81 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 81 In-stock
Estimated Time of Arrival: December 31
Solid
10 mg USD 74 In-stock
Estimated Time of Arrival: December 31
50 mg USD 285 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Fenticonazole Nitrate

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Fenticonazole Nitrate is an antifungal imidazole ring derivative. Fenticonazole Nitrate operates via hindering ergosterol integration, and sequentially destructing the cytoplasmatic outer membrane. Fenticonazole Nitrate is effective against Gram-positive bacteria, mycoses, and vaginal candidiasis[1][2].

In Vitro

Fenticonazole is an azole antifungal drug, used locally as the nitrate in the treatment of vulvovaginal candidiasis. It is active against a range of organisms including dermatophyte pathogens, Malassezia furfur, and Candida albicans[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

518.41

Formula

C24H21Cl2N3O4S

CAS No.
SMILES

[O-][N+](O)=O.ClC1=CC=C(C(OCC2=CC=C(SC3=CC=CC=C3)C=C2)CN4C=CN=C4)C(Cl)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (192.90 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9290 mL 9.6449 mL 19.2898 mL
5 mM 0.3858 mL 1.9290 mL 3.8580 mL
10 mM 0.1929 mL 0.9645 mL 1.9290 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (4.82 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (4.82 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (4.82 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation
References
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  • Molarity Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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Product Name:
Fenticonazole Nitrate
Cat. No.:
HY-B0359
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