Miconazole-d5 nitrate (2,4-Dichlorobenzyloxy-d5)
Miconazole-d5 (nitrate) (2,4-Dichlorobenzyloxy-d5) is the deuterium labeled Miconazole nitrate. Miconazole nitrate (R18134 nitrate) is an imidazole antifungal agent. Miconazole nitrate also has antibacterial effects.
For research use only. We do not sell to patients.
- CAS No.: 1398065-80-9
- Formula: C18H10D5Cl4N3O4
- Molecular Weight:484.17
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1398065-80-9
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Unlabeled Cas 22832-87-7
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Molecular Weight 484.17
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Formula C18H10D5Cl4N3O4
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SMILES
ClC(C([2H])=C(C([2H])=C1[2H])Cl)=C1C([2H])([2H])OC(C2=C(C=C(C=C2)Cl)Cl)CN3C=CN=C3.[O-][N+](O)=O
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Synonyms
R18134-d5 nitrate (2,4-Dichlorobenzyloxy-d5)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. http://en.wikipedia.org/wiki/Miconazole
[3]. Nenoff P, et al. New insights on the antibacterial efficacy of miconazole in vitro. Mycoses. 2017 Aug;60(8):552-557. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Miconazole-d5 nitrate (2,4-Dichlorobenzyloxy-d5) Related Classifications
HY-B0454AS Related Classifications
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