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Cat. No.: HY-N2079A

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(-)-Securinine nitrate

2 Cited Publications

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Based on 2 publication(s) in Google Scholar

(-)-Securinine nitrate is an alkaloid and also a GABA_A receptor antagonist. (-)-Securinine nitrate can be derived from plants.

For research use only. We do not sell to patients.

CAS No.: 7104-26-9
Formula: C₁₃H₁₆N₂O₅
Molecular Weight:280.28

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

(-)-Securinine nitrate Chemical Structure

CAS No.: 7104-26-9

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Fluorescent Dye

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Biological Activity

Description

(-)-Securinine nitrate is an alkaloid and also a GABA_A receptor antagonist. (-)-Securinine nitrate can be derived from plants^[1]^[2].

Chemical Information

CAS No. 7104-26-9
Molecular Weight 280.28
Formula C₁₃H₁₆N₂O₅
SMILES

O=C(O1)C=C2[C@@]13[C@](CCCC4)([H])N4[C@](C3)([H])C=C2.O[N+]([O-])=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (2)

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Journal Impact Factor

Nat Commun

Intraovarian injection of securinine stimulates the growth of small ovarian follicles by reducing stromal suppression. [Abstract]

2026 Apr 13;17(1):5061. PMID: 41974717
Cell Death Dis

Single-cell transcriptome profiles the heterogeneity of tumor cells and microenvironments for different pathological endometrial cancer and identifies specific sensitive drugs. [Abstract]

2024 Aug 7;15(8):571. PMID: 39112478

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Stefanowicz-Hajduk J, et al. Securinine from Phyllanthus glaucus Induces Cell Cycle Arrest and Apoptosis in Human Cervical Cancer HeLa Cells. PLoS One. 2016 Oct 28;11(10):e0165372. [Content Brief]

[2]. Kalpana Gupta, et al. Securinine, a Myeloid Differentiation Agent with Therapeutic Potential for AML. PLoS One. 2011; 6(6): e21203. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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(-)-Securinine nitrate

2 Cited Publications

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(-)-Securinine nitrate

Publications Citing Use of MedChemExpress (MCE) (-)-Securinine nitrate

Biological Activity

Chemical Information

Publications (2)

Purity & Documentation

References

Calculators

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(-)-Securinine nitrate Related Classifications

HY-N2079A Related Classifications