7104-26-9
7104-26-9
Chemical Structure
(-)-Securinine nitrate
- CAS No.: 7104-26-9
- Formula:C13H16N2O5
- Molecular Weight:280.28
IUPAC Name: (6S,11aR,11bS)-9,10,11,11a-tetrahydro-8H-6,11b-methanofuro[2,3-c]pyrido[1,2-a]azepin-2(6H)-one nitrate
InChIKey: GTMBYDCKQUSFCT-CSTPHZADSA-N
SMILES: O=C(O1)C=C2[C@@]13[C@](CCCC4)([H])N4[C@](C3)([H])C=C2.O[N+]([O-])=O
Biological Activity: (-)-Securinine nitrate is an alkaloid and also a GABAA receptor antagonist. (-)-Securinine nitrate can be derived from plants[1][2].
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(-)-Securinine nitrate | (-)-Securinine nitrate is an alkaloid and also a GABAA receptor antagonist. (-)-Securinine nitrate can be derived from plants. | |||||||||||||||||||||
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References
- [1]. Stefanowicz-Hajduk J, et al. Securinine from Phyllanthus glaucus Induces Cell Cycle Arrest and Apoptosis in Human Cervical Cancer HeLa Cells. PLoS One. 2016 Oct 28;11(10):e0165372. [Content Brief]
- [2]. Kalpana Gupta, et al. Securinine, a Myeloid Differentiation Agent with Therapeutic Potential for AML. PLoS One. 2011; 6(6): e21203. [Content Brief]
Keywords
