Search Result
Results for "
alcohol metabolite
" in MedChemExpress (MCE) Product Catalog:
10
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-B0876
-
|
4-Methylpyrazole
|
Cytochrome P450
|
Metabolic Disease
|
|
Fomepizole (4-Methylpyrazole) is a potent cytochrome P450 (CYP2E1) inhibitor. Fomepizole is a competitive inhibitor of the enzyme alcohol dehydrogenase. Fomepizole blocks further conversion of methanol and ethylene glycol to toxic metabolites. Fomepizole has the potential for an antidote for ethylene glycol or methanol poisoning .
|
-
-
- HY-W010155
-
-
-
- HY-N6662
-
-
-
- HY-113093
-
|
|
Endogenous Metabolite
Toll-like Receptor (TLR)
|
Neurological Disease
|
|
Ethyl glucuronide is an endogenous metabolite. Ethyl glucuronide is the metabolite of ethanol. Ethyl glucuronide is a biomarker for ethanol exposure that accumulates in hair and reflects the alcohol intake over a time period. Ethyl glucuronide is the agonist for TLR4 .
|
-
-
- HY-G0022
-
|
13-Dihydroadriamycin hydrochloride
|
Drug Metabolite
|
Cancer
|
|
Doxorubicinol hydrochloride (13-Dihydroadriamycin hydrochloride) is a secondary alcohol metabolite of Doxorubicin .
|
-
-
- HY-W041019
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
5-Hydroxytryptophol is a mammalian serotonin metabolite that can be used as a sensitive biomarker for recent alcohol intake. 5-Hydroxytryptophol is formed by alcohol-induced changes in the serotonin metabolic pathway and is excreted in the urine as a glucuronic acid conjugate. 5-Hydroxytryptophol is elevated in urine excretion and can be used clinically to monitor alcohol intake in scenarios such as alcohol relapse .
|
-
-
- HY-107858
-
|
3,4-Dimethoxybenzyl alcohol
|
Endogenous Metabolite
Bacterial
|
Infection
|
|
Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) is a secondary metabolite of lignin-degrading fungi, commonly used as a substrate for lignin peroxidase (LiP) to measure lignin degradation activity. Veratryl alcohol protects LiP from inactivation by H2O2 and prevents the accumulation of LiP III compounds. Veratryl alcohol also acts as a stabilizer for manganese-dependent peroxidases (MnP). Veratryl alcohol is a quorum-sensing inhibitor (QSI) and exhibits antibacterial efficacy .
|
-
-
- HY-N1867
-
|
|
PPAR
|
Metabolic Disease
|
|
trans-Cinnamyl alcohol is a trans-isomer of Cinnamyl alcohol. Cinnamyl Alcohol is an active component from chestnut flower, inhibits increased PPARγ expression, with anti-obesity activity. trans-Cinnamyl alcohol, belongs to the class of organic compounds known as cinnamyl alcohols, is a primary metabolite .
|
-
-
- HY-113093S
-
-
-
- HY-N7513
-
|
|
TNF Receptor
Drug Metabolite
|
Cardiovascular Disease
|
|
Homovanillyl alcohol is a biological metabolite of Hydroxytyrosol. Hydroxytyrosol is a phenolic compound that is present in virgin olive oil (VOO) and wine. Homovanillyl alcohol protects red blood cells (RBCs) from oxidative injury and has protective effect on cardiovascular disease .
|
-
-
- HY-14572
-
|
SN 27858
|
DNA Alkylator/Crosslinker
Drug Metabolite
|
Cancer
|
|
PR-104A (SN 27858) is the alcohol metabolite of phosphate proagent PR-104. PR-104A is a hypoxia-selective DNA cross-linking agent/DNA-damaging agent and cytotoxin. Antitumor Activity . PR-104A is metabolized under hypoxia by the 1-electron NADPH:cytochrome P450 oxidoreductase. PR-104A can be used for the research of relapsed/refractory T-lineage acute lymphoblastic leukemia (T-ALL) .
|
-
-
- HY-136410
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
4-hydroxy Nonenal Mercapturic Acid is a major urinary metabolite of 4-hydroxy-2-nonenal (4-HNE). 4-hydroxy Nonenal Mercapturic Acid metabolites include reduced alcohols, aldehydes, and carboxylic acids, which further form gamma-lactols and gamma-lactones, resulting in 4-5 final urinary metabolites in vivo. 4-hydroxy Nonenal Mercapturic Acid can be used as a biomarker to assess oxidative stress .
|
-
-
- HY-B0876A
-
|
4-Methylpyrazole hydrochloride
|
Cytochrome P450
|
Metabolic Disease
|
|
Fomepizole (4-Methylpyrazole) hydrochloride is a potent and orally active cytochrome P450 (CYP2E1) inhibitor. Fomepizole hydrochloride is a competitive inhibitor of the enzyme alcohol dehydrogenase. Fomepizole hydrochloride blocks further conversion of methanol and ethylene glycol to toxic metabolites. Fomepizole hydrochloride has the potential for an antidote for ethylene glycol or methanol poisoning .
|
-
-
- HY-W010155R
-
|
Indole-3-ethanol (Standard)
|
Reference Standards
Endogenous Metabolite
Apoptosis
Caspase
Bacterial
|
Infection
Cardiovascular Disease
Neurological Disease
Metabolic Disease
Inflammation/Immunology
|
|
Tryptophol (Standard) (Indole-3-ethanol (Standard)) is an analytical standard of Tryptophol (HY-W010155). This product is intended for use in research and analytical applications.Tryptophol is an aromatic alcohol and secondary metabolite produced by microorganisms. Tryptophol induces Apoptosis and cleavage of caspase-8. Tryptophol inhibits Cunninghamella blakesleeana biofilm. Tryptophol has anti-phage infection, biofilm formation regulation, anti-inflammatory, hemolytic, sleep induction, temperature change, seizure susceptibility and immune regulation activities. Tryptophol is used in the research of African trypanosomiasis, sleep disorders, epilepsy.
|
-
-
- HY-W750342
-
-
-
- HY-N3102A
-
|
(E)-p-Hydroxycinnamyl alcohol
|
Others
|
Inflammation/Immunology
|
|
(E)-p-Coumaryl alcohol is a metabolite of coumarin that has significant cytotoxicity. (E)-p-Coumaryl alcohol can be isolated from Alpinia officinarum and Rhodiola rosea and can be used for inflammation research .
|
-
-
- HY-W145584
-
-
-
- HY-12770
-
-
-
- HY-113471
-
|
|
Apoptosis
HSV
|
Infection
Inflammation/Immunology
Cancer
|
|
Perillic acid is the metabolite of Perillyl alcohol (HY-N7000). Perillic acid induces lung cancer cell cycle arrest and apoptosis. Perillic acid shows anti-HSV-1 and immunomodulatory activities .
|
-
-
- HY-N1753
-
|
Dihydro-p-coumaryl alcohol; 3-(p-Hydroxyphenyl)propyl alcohol
|
Endogenous Metabolite
|
Others
|
|
3-(4-Hydroxyphenyl)-1-propanol (Dihydro-p-coumaryl alcohol) is a metabolite. 3-(4-Hydroxyphenyl)-1-propanol can be isolated from P. radiate callus cultures. 3-(4-Hydroxyphenyl)-1-propanol is associated with CAD activity .
|
-
-
- HY-N7731A
-
|
(R)-Lavandulol
|
Others
|
Others
|
|
(-)-Lavandulol is the isomer of (±)-Lavandulol (HY-N7731). (±)-Lavandulol is an irregular monoterpene alcohol. (±)-Lavandulol can be transformed by a fungal strain Rhizopus oryzae into corresponding oxygenated metabolite .
|
-
-
- HY-W681822
-
-
-
- HY-G0008A
-
|
Mebeverine metabolite O-desmethyl Mebeverine alcohol hydrochloride
|
Adrenergic Receptor
Drug Metabolite
|
Metabolic Disease
|
|
O-Desmethyl Mebeverine alcohol hydrochloride is a metabolite of Mebeverine, which is a potent α1 repector inhibitor, causing relaxation of the gastrointestinal tract.
|
-
-
- HY-G0008
-
|
Mebeverine metabolite O-desmethyl Mebeverine alcohol
|
Adrenergic Receptor
Drug Metabolite
|
Metabolic Disease
|
|
O-Desmethyl Mebeverine alcohol is a metabolite of Mebeverine, which is a potent α1 repector inhibitor, causing relaxation of the gastrointestinal tract.
|
-
-
- HY-W588249
-
|
|
Bacterial
Endogenous Metabolite
|
Infection
|
|
Sabinene hydrate is a volatile organic compound of a bicyclic monoterpene alcohol. Sabinene hydrate, as a plant secondary metabolite, is naturally present in various plants and their essential oils. Sabinene hydrate exhibits broad-spectrum but varying-intensity antibacterial activity, with the greatest sensitivity to Gram-positive bacteria, especially Bacillus subtilis (MIC = 0.0312 mg/mL) and Staphylococcus aureus (MIC = 0.0625 mg/mL). Sabinene hydrate also shows certain sensitivity to Escherichia coli and Candida albicans, with MIC values of 0.125 mg/mL for both. Sabinene hydrate can be used in the research of the ecological functions of plant defense substances .
|
-
-
- HY-W041019S
-
|
|
Endogenous Metabolite
|
Others
|
|
5-Hydroxytryptophol-d4 is the deuterium labeled 5-Hydroxytryptophol. 5-Hydroxytryptophol is a mammalian serotonin metabolite, acting as a marker of acute alcohol consumption.
|
-
-
- HY-12770S1
-
-
-
- HY-19021
-
|
|
mGluR
|
Neurological Disease
|
|
ADD-17014 is a L-Glu antagonist. ADD-17014 impairs presynaptic excitatory amino acid L-Glu neurotransmission. ADD-17014 is a prodrug of its β-amino alcohol metabolite, and the metabolite acts as a NMDA receptor antagonist by binding to the MK-801 site located inside the NMDA receptor or ion channel. ADD-17014 has an anticonvulsant and anti-ischemic activity. ADD-17014 can be used for neurodegenerative diseases like Parkinson’s disease, Alzheimer’s disease and stroke research .
|
-
-
- HY-33914
-
|
|
Drug Metabolite
|
Metabolic Disease
|
|
4-Hydroxymethylpyrazole is the primary metabolite of Fomepizole (HY-B0876) produced through hepatic oxidative metabolism. 4-Hydroxymethylpyrazole exhibits a plasma concentration that is positively correlated with the administered dosage of Fomepizole, and it demonstrates a relatively short half-life. 4-Hydroxymethylpyrazole demonstrates inhibitory effects on alcohol dehydrogenase (ADH) in both humans and monkeys, but its inhibition constant is significantly higher than that of Fomepizole, rendering its in vivo impact negligible .
|
-
-
- HY-N1867R
-
|
|
Reference Standards
PPAR
|
Metabolic Disease
|
|
trans-Cinnamyl alcohol is a trans-isomer of Cinnamyl alcohol. Cinnamyl Alcohol is an active component from chestnut flower, inhibits increased PPARγ expression, with anti-obesity activity. trans-Cinnamyl alcohol, belongs to the class of organic compounds known as cinnamyl alcohols, is a primary metabolite .
|
-
-
- HY-12770R
-
|
Mebeverine metabolite Mebeverine alcohol (Standard)
|
Reference Standards
Drug Metabolite
|
Neurological Disease
|
|
Mebeverine alcohol (Standard) is an analytical standard for Mebeverine alcohol. This product is intended for research and analytical applications. Eperezolid (PNU-100592) is an orally active protein synthesis inhibitor that targets the bacterial 50S ribosomal subunit. Eperezolid competitively binds to a specific site on the ribosomal 50S subunit (overlapping with the binding sites of Chloramphenicol (HY-B0239) and Lincomycin (HY-117660)) to inhibit the translation initiation stage and exert antibacterial activity. Eperezolid can induce host cell autophagy to enhance the clearance of intracellular mycobacteria, and its MIC90 for Staphylococcus aureus and Enterococcus is 1-4 μg/mL. Eperezolid is mainly used for antibacterial research on infections with Gram-positive bacteria such as methicillin-resistant (HY-121544) Staphylococci and vancomycin-resistant (HY-B0671) Enterococci, as well as infections with intracellular bacteria such as Mycobacterium tuberculosis .
|
-
-
- HY-G0008AR
-
|
Mebeverine metabolite O-desmethyl Mebeverine alcohol hydrochloride (Standard)
|
Reference Standards
Adrenergic Receptor
Drug Metabolite
|
Metabolic Disease
|
|
Diethyl phthalate (Standard) is the analytical standard of Diethyl phthalate. This product is intended for research and analytical applications. Diethyl phthalate is an endocrine disruptor that has the activity of affecting the apoptosis system of PC12 cells. Diethyl phthalate is widely used in a variety of plastics and personal care products. Diethyl phthalate has shown the potential to induce male reproductive toxicity unrelated to androgens in animal experiments .
|
-
-
- HY-143826S
-
|
Mebeverine metabolite O-desmethyl Mebeverine alcohol-d5 citrate
|
Isotope-Labeled Compounds
|
Others
|
|
O-Desmethyl Mebeverine alcohol-d5 (citrate) is the deuterium labeled O-Desmethyl Mebeverine alcohol citrate .
|
-
-
- HY-12770S
-
-
-
- HY-W041019R
-
|
|
Reference Standards
Endogenous Metabolite
|
Metabolic Disease
|
|
5-Hydroxytryptophol is a mammalian serotonin metabolite that can be used as a sensitive biomarker for recent alcohol intake. 5-Hydroxytryptophol is formed by alcohol-induced changes in the serotonin metabolic pathway and is excreted in the urine as a glucuronic acid conjugate. 5-Hydroxytryptophol is elevated in urine excretion and can be used clinically to monitor alcohol intake in scenarios such as alcohol relapse .
|
-
-
- HY-W274501
-
-
-
- HY-W738271
-
|
3,4-Dimethoxybenzyl alcohol-13C
|
Isotope-Labeled Compounds
Bacterial
Endogenous Metabolite
|
Infection
|
|
Veratryl alcohol- 13C (3,4-Dimethoxybenzyl alcohol- 13C) is the 13C-labeled Veratryl alcohol (HY-107858). Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) is a secondary metabolite of lignin-degrading fungi, commonly used as a substrate for lignin peroxidase (LiP) to measure lignin degradation activity. Veratryl alcohol protects LiP from inactivation by H2O2 and prevents the accumulation of LiP III compounds. Veratryl alcohol also acts as a stabilizer for manganese-dependent peroxidases (MnP). Veratryl alcohol is a quorum-sensing inhibitor (QSI) and exhibits antibacterial efficacy .
|
-
-
- HY-N7731
-
|
|
Others
|
Others
|
|
(±)-Lavandulol is an irregular monoterpene alcohol. (±)-Lavandulol can be transformed by a fungal strain Rhizopus oryzae into corresponding oxygenated metabolite .
|
-
-
- HY-Z12431
-
|
KMD-3293
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Silodosin carboxylic acid impurity (KMD-3293) is an inactive silodosin metabolite. Silodosin carboxylic acid impurity is the major metabolite that can be generated via oxidation by alcohol and aldehyde dehydrogenase. Silodosin carboxylic acid impurity can be studied in research for benign prostatic hyperplasia .
|
-
-
- HY-N7731R
-
|
|
Others
Reference Standards
|
Others
|
|
(±)-Lavandulol (Standard) is the analytical standard of (±)-Lavandulol. This product is intended for research and analytical applications. (±)-Lavandulol is an irregular monoterpene alcohol. (±)-Lavandulol can be transformed by a fungal strain Rhizopus oryzae into corresponding oxygenated metabolite .
|
-
-
- HY-W145584S
-
-
-
- HY-N5158B
-
|
|
Antibiotic
Endogenous Metabolite
|
Infection
|
|
(5S)-Neosamine C is an aminocyclic alcohol antibiotic derived from microbial secondary metabolites. (5S)-Neosamine C has a cyclized structure and can be used for biosynthesis of Neomycins (HY-B0470).
|
-
-
- HY-116802
-
|
|
Drug Derivative
Herbicide
|
Others
|
|
Bromobutide is an active ingredient in herbicides that kill weeds. Bromobutide has the highest control effect on Scirpus juncoides and Monochloa vaginalis, but has no inhibitory effect on weed seed germination. The main metabolites of bromobutide in rats are alcohol or phenol glucuronides, which enter the enterohepatic circulation .
|
-
-
- HY-B0876R
-
|
4-Methylpyrazole (Standard)
|
Reference Standards
Cytochrome P450
|
Metabolic Disease
|
|
Fomepizole (Standard) is the analytical standard of Fomepizole. This product is intended for research and analytical applications. Fomepizole (4-Methylpyrazole) is a potent cytochrome P450 (CYP2E1) inhibitor. Fomepizole is a competitive inhibitor of the enzyme alcohol dehydrogenase. Fomepizole blocks further conversion of methanol and ethylene glycol to toxic metabolites. Fomepizole has the potential for an antidote for ethylene glycol or methanol poisoning .
|
-
-
- HY-N1753R
-
|
Dihydro-p-coumaryl alcohol (Standard); 3-(p-Hydroxyphenyl)propyl alcohol (Standard)
|
Reference Standards
Endogenous Metabolite
|
Others
|
|
3-(4-Hydroxyphenyl)-1-propanol (Standard) is an analytical standard of 3-(4-Hydroxyphenyl)-1-propanol (HY-N1753). This product is intended for research and analytical applications. 3-(4-Hydroxyphenyl)-1-propanol (Dihydro-p-coumaryl alcohol) is a metabolite. 3-(4-Hydroxyphenyl)-1-propanol can be isolated from P. radiate callus cultures. 3-(4-Hydroxyphenyl)-1-propanol is associated with CAD activity .
|
-
-
- HY-N3102AR
-
|
(E)-p-Hydroxycinnamyl alcohol (Standard)
|
Others
Reference Standards
|
Inflammation/Immunology
|
|
(E)-p-Coumaryl alcohol is a metabolite of coumarin that has significant cytotoxicity. (E)-p-Coumaryl alcohol can be isolated from Alpinia officinarum and Rhodiola rosea and can be used for inflammation research .
|
-
-
- HY-W1121873
-
|
|
Others
|
Inflammation/Immunology
|
|
β-Caryophyllene alcohol is an active metabolite of β-caryophyllene (HY-N1415) with potent anti-asthma and anti-inflammation activity. β-Caryophyllene alcohol shows significant anti-asthmatic effect in guinea pigs. β-Caryophyllene alcohol can be used for asthma and inflammation research .
|
-
-
- HY-N6662S
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
(+)-Longifolene- 13C,d2 is the 13C- and deuterium labeled (+)-Longifolene (HY-N6662). (+)-Longifolene is a sesquiterpenoid and a metabolite in rabbits. (+)-Longifolen is converted to primary, secondary or tertiary alcohols in rabbits, among which the primary alcohol is predominant .
|
-
-
- HY-W557590
-
|
|
Drug Metabolite
|
Others
|
|
Nabumetone alcohol is a metabolite of Nabumetone (HY-B0559) . Nabumetone is an orally active non-acidic anti-inflammatory agent, acts as a potent and selective COX-2 inhibitor, and is the proagent of the active metaboliteα-Demethylnaproxen (HY-W086896). Nabumetone can inhibit cancer cells proliferation and relieve gastric ulcers.
|
-
-
- HY-156196
-
|
|
Syk
|
Inflammation/Immunology
|
|
BI 894416 is a spleen tyrosine kinase (SYK) inhibitor. BI 894416 has a deuterium-labeled derivative that can be used as an internal standard for bioanalytical studies. BI 894416 is applicable to the research of severe asthma .
|
-
- HY-W724345
-
|
4-Methylpyrazole-d2
|
Isotope-Labeled Compounds
Cytochrome P450
|
Metabolic Disease
|
|
Fomepizole-d2 (4-Methylpyrazole-d2) is the deuterium labeled Fomepizole (HY-B0876). Fomepizole (4-Methylpyrazole) is a potent cytochrome P450 (CYP2E1) inhibitor. Fomepizole is a competitive inhibitor of the enzyme alcohol dehydrogenase. Fomepizole blocks further conversion of methanol and ethylene glycol to toxic metabolites. Fomepizole has the potential for an antidote for ethylene glycol or methanol poisoning .
|
-
- HY-33914R
-
|
|
Drug Metabolite
Reference Standards
|
Metabolic Disease
|
|
4-Hydroxymethylpyrazole (Standard) is an analytical standard for 4-Hydroxymethylpyrazole (HY-33914). This product is intended for research and analytical applications. 4-Hydroxymethylpyrazole is the primary metabolite of fomepizole (HY-B0876) via hepatic oxidative metabolism. 4-Hydroxymethylpyrazole exhibits a plasma concentration that is positively correlated with the administered dosage of Fomepizole, and it demonstrates a relatively short half-life. 4-Hydroxymethylpyrazole inhibits alcohol dehydrogenase (ADH) in humans and monkeys, but the inhibition constant is much higher than that of fomepizole and is therefore negligible in vivo
|
-
- HY-167246
-
|
|
Insecticide
|
Infection
|
|
Profluthrin is a pyrethroid insecticide. Profluthrin can be used as mothproof repellents for clothes .
|
-
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-W010155
-
-
-
- HY-N6662
-
-
-
- HY-113093
-
-
-
- HY-W041019
-
-
-
- HY-107858
-
-
-
- HY-N1867
-
|
|
Natural Products
Rosaceae
Plants
Source Classification
|
PPAR
|
|
trans-Cinnamyl alcohol is a trans-isomer of Cinnamyl alcohol. Cinnamyl Alcohol is an active component from chestnut flower, inhibits increased PPARγ expression, with anti-obesity activity. trans-Cinnamyl alcohol, belongs to the class of organic compounds known as cinnamyl alcohols, is a primary metabolite .
|
-
-
- HY-N7513
-
-
-
- HY-W010155R
-
-
-
- HY-N3102A
-
-
-
- HY-W145584
-
-
-
- HY-N7731A
-
-
-
- HY-W588249
-
|
|
Structural Classification
Other Monoterpenes
Juniperus communis L.
Cupressaceae
Terpenoids
Plants
Source Classification
|
Bacterial
Endogenous Metabolite
|
|
Sabinene hydrate is a volatile organic compound of a bicyclic monoterpene alcohol. Sabinene hydrate, as a plant secondary metabolite, is naturally present in various plants and their essential oils. Sabinene hydrate exhibits broad-spectrum but varying-intensity antibacterial activity, with the greatest sensitivity to Gram-positive bacteria, especially Bacillus subtilis (MIC = 0.0312 mg/mL) and Staphylococcus aureus (MIC = 0.0625 mg/mL). Sabinene hydrate also shows certain sensitivity to Escherichia coli and Candida albicans, with MIC values of 0.125 mg/mL for both. Sabinene hydrate can be used in the research of the ecological functions of plant defense substances .
|
-
-
- HY-33914
-
-
-
- HY-N1867R
-
-
-
- HY-W041019R
-
-
-
- HY-W274501
-
-
-
- HY-N7731
-
-
-
- HY-N7731R
-
|
|
Natural Products
Microorganisms
Source Classification
|
Others
Reference Standards
|
|
(±)-Lavandulol (Standard) is the analytical standard of (±)-Lavandulol. This product is intended for research and analytical applications. (±)-Lavandulol is an irregular monoterpene alcohol. (±)-Lavandulol can be transformed by a fungal strain Rhizopus oryzae into corresponding oxygenated metabolite .
|
-
-
- HY-N5158B
-
-
-
- HY-N3102AR
-
-
-
- HY-W1121873
-
-
-
- HY-33914R
-
|
|
Natural Products
Endogenous metabolite
Source Classification
|
Drug Metabolite
Reference Standards
|
|
4-Hydroxymethylpyrazole (Standard) is an analytical standard for 4-Hydroxymethylpyrazole (HY-33914). This product is intended for research and analytical applications. 4-Hydroxymethylpyrazole is the primary metabolite of fomepizole (HY-B0876) via hepatic oxidative metabolism. 4-Hydroxymethylpyrazole exhibits a plasma concentration that is positively correlated with the administered dosage of Fomepizole, and it demonstrates a relatively short half-life. 4-Hydroxymethylpyrazole inhibits alcohol dehydrogenase (ADH) in humans and monkeys, but the inhibition constant is much higher than that of fomepizole and is therefore negligible in vivo
|
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-113093S
-
|
|
|
Ethyl glucuronide-d5 is the deuterium labeled Ethyl glucuronide (HY-113093) . Ethyl glucuronide is an endogenous metabolite. Ethyl glucuronide is the metabolite of ethanol. Ethyl glucuronide is a biomarker for ethanol exposure that accumulates in hair and reflects the alcohol intake over a time period. Ethyl glucuronide is the agonist for TLR4 .
|
-
-
- HY-W750342
-
|
|
|
Tryptophol-d4 (Indole-3-ethanol-d4) is the deuterium labeled Tryptophol (HY-W010155). Tryptophol is an aromatic alcohol and secondary metabolite produced by microorganisms. Tryptophol induces apoptosis and cleavage of caspase-8. Tryptophol inhibits Cunninghamella blakesleeana biofilm. Tryptophol has anti-phage infection, biofilm formation regulation, anti-inflammatory, hemolytic, sleep induction, temperature change, seizure susceptibility and immune regulation activities. Tryptophol is used in the research of African trypanosomiasis, sleep disorders, epilepsy .
|
-
-
- HY-W041019S
-
|
|
|
5-Hydroxytryptophol-d4 is the deuterium labeled 5-Hydroxytryptophol. 5-Hydroxytryptophol is a mammalian serotonin metabolite, acting as a marker of acute alcohol consumption.
|
-
-
- HY-12770S1
-
|
|
|
Mebeverine alcohol-d3 (Mebeverine metabolite Mebeverine alcohol-d3) is deuterium labeled Mebeverine alcohol.
|
-
-
- HY-143826S
-
|
|
|
O-Desmethyl Mebeverine alcohol-d5 (citrate) is the deuterium labeled O-Desmethyl Mebeverine alcohol citrate .
|
-
-
- HY-12770S
-
|
|
|
Mebeverine alcohol-d5 is the deuterium labeled Mebeverine alcohol, which is a metabolite of Mebeverine.
|
-
-
- HY-W738271
-
|
|
|
Veratryl alcohol- 13C (3,4-Dimethoxybenzyl alcohol- 13C) is the 13C-labeled Veratryl alcohol (HY-107858). Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) is a secondary metabolite of lignin-degrading fungi, commonly used as a substrate for lignin peroxidase (LiP) to measure lignin degradation activity. Veratryl alcohol protects LiP from inactivation by H2O2 and prevents the accumulation of LiP III compounds. Veratryl alcohol also acts as a stabilizer for manganese-dependent peroxidases (MnP). Veratryl alcohol is a quorum-sensing inhibitor (QSI) and exhibits antibacterial efficacy .
|
-
-
- HY-W145584S
-
|
|
|
D-Iditol- 13C is the 13C labeled D-Iditol. D-Iditol is a fungal metabolite, a sugar alcohol that accumulates in galactokinase deficiency. D-Iditol may have potential antitumour activity .
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- HY-N6662S
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(+)-Longifolene- 13C,d2 is the 13C- and deuterium labeled (+)-Longifolene (HY-N6662). (+)-Longifolene is a sesquiterpenoid and a metabolite in rabbits. (+)-Longifolen is converted to primary, secondary or tertiary alcohols in rabbits, among which the primary alcohol is predominant .
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- HY-W724345
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Fomepizole-d2 (4-Methylpyrazole-d2) is the deuterium labeled Fomepizole (HY-B0876). Fomepizole (4-Methylpyrazole) is a potent cytochrome P450 (CYP2E1) inhibitor. Fomepizole is a competitive inhibitor of the enzyme alcohol dehydrogenase. Fomepizole blocks further conversion of methanol and ethylene glycol to toxic metabolites. Fomepizole has the potential for an antidote for ethylene glycol or methanol poisoning .
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