1. GPCR/G Protein Neuronal Signaling Metabolic Enzyme/Protease
  2. Adrenergic Receptor Drug Metabolite
  3. O-Desmethyl Mebeverine alcohol hydrochloride

O-Desmethyl Mebeverine alcohol hydrochloride  (Synonyms: Mebeverine metabolite O-desmethyl Mebeverine alcohol hydrochloride)

Cat. No.: HY-G0008A Purity: ≥98.0%
COA Handling Instructions

O-Desmethyl Mebeverine alcohol hydrochloride is a metabolite of Mebeverine, which is a potent α1 repector inhibitor, causing relaxation of the gastrointestinal tract.

For research use only. We do not sell to patients.

O-Desmethyl Mebeverine alcohol hydrochloride Chemical Structure

O-Desmethyl Mebeverine alcohol hydrochloride Chemical Structure

CAS No. : 856620-39-8

Size Price Stock Quantity
2 mg USD 99 In-stock
5 mg USD 160 In-stock
10 mg USD 260 In-stock
50 mg USD 960 In-stock
100 mg   Get quote  
200 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Other Forms of O-Desmethyl Mebeverine alcohol hydrochloride:

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Description

O-Desmethyl Mebeverine alcohol hydrochloride is a metabolite of Mebeverine, which is a potent α1 repector inhibitor, causing relaxation of the gastrointestinal tract.

IC50 & Target

α1 repector

Molecular Weight

287.83

Formula

C15H26ClNO2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OCCCCN(CC)C(C)CC1=CC=C(O)C=C1.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 75 mg/mL (260.57 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4743 mL 17.3714 mL 34.7427 mL
5 mM 0.6949 mL 3.4743 mL 6.9485 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (347.43 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.4743 mL 17.3714 mL 34.7427 mL 86.8568 mL
5 mM 0.6949 mL 3.4743 mL 6.9485 mL 17.3714 mL
10 mM 0.3474 mL 1.7371 mL 3.4743 mL 8.6857 mL
15 mM 0.2316 mL 1.1581 mL 2.3162 mL 5.7905 mL
20 mM 0.1737 mL 0.8686 mL 1.7371 mL 4.3428 mL
25 mM 0.1390 mL 0.6949 mL 1.3897 mL 3.4743 mL
30 mM 0.1158 mL 0.5790 mL 1.1581 mL 2.8952 mL
40 mM 0.0869 mL 0.4343 mL 0.8686 mL 2.1714 mL
50 mM 0.0695 mL 0.3474 mL 0.6949 mL 1.7371 mL
60 mM 0.0579 mL 0.2895 mL 0.5790 mL 1.4476 mL
80 mM 0.0434 mL 0.2171 mL 0.4343 mL 1.0857 mL
100 mM 0.0347 mL 0.1737 mL 0.3474 mL 0.8686 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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O-Desmethyl Mebeverine alcohol hydrochloride Related Classifications

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Product Name:
O-Desmethyl Mebeverine alcohol hydrochloride
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