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Pathways Recommended:	Cell Cycle/DNA Damage

Results for "

citric acid cycle

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (1) Apoptosis (16) Bacterial (16) Biochemical Assay Reagents (1) DNA/RNA Synthesis (1) Endogenous Metabolite (44) Environmental Pollutants (7) Fatty Acid Synthase (FASN) (4) Isocitrate Dehydrogenase (IDH) (2) Isotope-Labeled Compounds (10) Malate Dehydrogenase (MDH) (1) Mitochondrial Metabolism (3) NF-κB (4) Orphan GPCR (1) Oxidative Phosphorylation (1) p38 MAPK (4) Reactive Oxygen Species (ROS) (2) Reference Standards (11) TRP Channel (1)
By Research Areas:	Cancer (21) Cardiovascular Disease (20) Infection (16) Inflammation/Immunology (19) Metabolic Disease (40) Neurological Disease (1)

By Targets:

Antibiotic (1)

Apoptosis (16)

Bacterial (16)

Biochemical Assay Reagents (1)

DNA/RNA Synthesis (1)

Endogenous Metabolite (44)

Environmental Pollutants (7)

Fatty Acid Synthase (FASN) (4)

Isocitrate Dehydrogenase (IDH) (2)

Isotope-Labeled Compounds (10)

Malate Dehydrogenase (MDH) (1)

Mitochondrial Metabolism (3)

NF-κB (4)

Orphan GPCR (1)

Oxidative Phosphorylation (1)

p38 MAPK (4)

Reactive Oxygen Species (ROS) (2)

Reference Standards (11)

TRP Channel (1)

By Research Areas:

Cancer (21)

Cardiovascular Disease (20)

Infection (16)

Inflammation/Immunology (19)

Metabolic Disease (40)

Neurological Disease (1)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

GMP Molecules

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-128851

Coenzyme A 2 Publications Verification	Endogenous Metabolite Fatty Acid Synthase (FASN)	Metabolic Disease Cancer
Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .

HY-N1428

Citric acid Maximum Cited Publications 34 Publications Verification	Environmental Pollutants Endogenous Metabolite Bacterial Apoptosis	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-W015883

Fumaric acid 4 Publications Verification	Environmental Pollutants Endogenous Metabolite NF-κB p38 MAPK	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension .

HY-B2201

Citric acid trisodium Maximum Cited Publications 11 Publications Verification Sodium citrate; Trisodium citrate anhydrous	Environmental Pollutants Endogenous Metabolite Bacterial Apoptosis	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Citric acid trisodium (Sodium citrate) is a natural preservative and food tartness enhancer. Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid trisodium cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid trisodium is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-Y1311

Malic acid 4 Publications Verification Hydroxybutanedioic acid; E 296	Environmental Pollutants Endogenous Metabolite	Others
Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that occurs naturally in fruits like apples and pears with oral activities. Malic acid plays a role in many sour or tangy foods. Malic acid is an intermediate in the citric acid cycle .

HY-W009362

DL-Isocitric acid trisodium salt 2 Publications Verification	Endogenous Metabolite	Cardiovascular Disease
DL-Isocitric acid trisodium salt is an endogenous metabolite. DL-Isocitric acid trisodium salt is an intermediate product in the citric acid cycle. DL-Isocitric acid trisodium salt can be used as a marker for determining the composition of isocitrates in fruit products .

HY-134539

IMT1 5+ Cited Publications	Oxidative Phosphorylation Mitochondrial Metabolism DNA/RNA Synthesis	Metabolic Disease Cancer
IMT1 is a first-in-class specific and noncompetitive human mitochondrial RNA polymerase (POLRMT) inhibitor. IMT1 causes a conformational change of POLRMT, which blocks substrate binding and transcription in a dose-dependent way in vitro. IMT1 reduces deoxynucleoside triphosphate levels and citric acid cycle intermediates, resulting in a marked depletion of cellular amino acid levels. IMT1 has the potential for mitochondrial transcription disorders related diseases .

HY-137808

Succinyl-Coenzyme A sodium 3 Publications Verification Succinyl-CoA sodium	Endogenous Metabolite	Neurological Disease Metabolic Disease
Succinyl CoA (Succinyl-coenzyme A) sodium is a pivotal intermediate metabolite in the tricarboxylic acid cycle and a key coenzyme A metabolite. Succinyl CoA sodium is biosynthesized from α-ketoglutarate or propionyl-CoA. Succinyl CoA sodium acts as a critical precursor and substrate for heme biosynthesis and gluconeogenesis. Succinyl CoA sodium insufficiency caused by cobalamin deficiency is directly linked to growth retardation, impaired heme synthesis, tissue glycine accumulation and neurological abnormalities. Succinyl CoA sodium can be used in research on metabolic, neurological, and hematological abnormalities (such as porphyria) caused by nutritional vitamin B12 deficiency (leading to a lack of Succinyl-Coenzyme A synthesis) .

HY-128851B

Coenzyme A sodium 2 Publications Verification	Endogenous Metabolite Fatty Acid Synthase (FASN)	Metabolic Disease Cancer
Coenzyme A (CoASH) sodium is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .

HY-W010382

Oxaloacetic acid 2 Publications Verification 2-Oxosuccinic acid	Endogenous Metabolite Reactive Oxygen Species (ROS)	Metabolic Disease
Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis, whereby Oxaloacetic acid facilitates the clearance of reactive oxygen species (ROS) and improves mitochondrial function .

HY-N1428S1

Citric acid-13C6	Isotope-Labeled Compounds Endogenous Metabolite Apoptosis Bacterial	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Citric acid- ¹³C₆ is the ¹³C-labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-N1428A

Citric acid monohydrate 5+ Cited Publications	Environmental Pollutants Endogenous Metabolite Apoptosis Bacterial	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Citric acid monohydrate is a natural preservative and food tartness enhancer. Citric acid monohydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid monohydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid monohydrate is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-N1428S

Citric acid-d4	Isotope-Labeled Compounds Apoptosis Endogenous Metabolite Bacterial	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Citric acid-d₄ is the deuterium labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-W009156

Citric acid tripotassium hydrate 10+ Cited Publications Potassium citrate monohydrate	Environmental Pollutants Endogenous Metabolite Bacterial Apoptosis	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Citric acid tripotassium hydrate (Potassium citrate monohydrate) is a natural preservative and food tartness enhancer. Citric acid tripotassium hydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid tripotassium hydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid tripotassium hydrate is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-128851A

Coenzyme A trilithium 2 Publications Verification	Endogenous Metabolite Fatty Acid Synthase (FASN)	Metabolic Disease Cancer
Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .

HY-P2739

Citrate synthase	Endogenous Metabolite	Others
Citrate synthase is responsible for catalyzing the first reaction of the citric acid cycle: the condensation of acetyl-CoA and oxaloacetate to form citrate. Citrate synthase is localized within eukaryotic cells in the mitochondrial matrix .

HY-W015883A

Fumaric acid disodium 4 Publications Verification	Endogenous Metabolite NF-κB p38 MAPK	Cardiovascular Disease Inflammation/Immunology
Fumaric acid disodium is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid disodium exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid disodium can be used in the study of pregnancy-induced hypertension .

HY-W020215

Tricarballylic acid 1 Publications Verification	Mitochondrial Metabolism Endogenous Metabolite	Metabolic Disease
Tricarballylic acid is an orally active compound that can be produced by rumen microorganisms and has the activity of chelating magnesium. Tricarballylic acid is also a competitive inhibitor of aconitate hydratase, with a K_i value of 0.52 mM. Tricarballylic acid can inhibit the oxidation of acetate in the citric acid cycle and can be used in the research of ruminant tissue metabolism and grass tetany syndrome. In addition, Tricarballylic acid can be used to synthesize specific complexes and produce plasticizers .

HY-N1428R

Citric acid (standard) 5+ Cited Publications	Reference Standards Apoptosis Endogenous Metabolite Bacterial	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Citric acid (Standard) is the analytical standard of Citric acid (HY-N1428). This product is intended for research and analytical applications. Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-N1428S3

Citric acid-13C3	Isotope-Labeled Compounds Apoptosis Endogenous Metabolite Bacterial	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Citric acid- ¹³C₃ is the ¹³C-labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-W008606

Sodium citrate monobasic citric acid monosodium salt	Environmental Pollutants Endogenous Metabolite Bacterial Apoptosis	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Sodium citrate monobasic (Citric acid monosodium salt) is a natural preservative and food tartness enhancer. Sodium citrate monobasic induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Sodium citrate monobasic cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Sodium citrate monobasic is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-W017524

2-Methylpentanedioic acid 1 Publications Verification	Endogenous Metabolite	Others
2-Methylpentanedioic acid is a metabolite of succinic acid, a citric acid cycle intermediate.

HY-W010382S

Oxaloacetic acid-13C4 1 Publications Verification 2-Oxosuccinic acid-¹³C₄	Endogenous Metabolite Isotope-Labeled Compounds	Metabolic Disease
Oxaloacetic acid- ¹³C₄ is the ¹³C-labeled Oxaloacetic acid. Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis .

HY-148285

Succinyl CoA Succinyl-coenzyme A; S-(Hydrogen succinyl)coenzyme A	Endogenous Metabolite	Metabolic Disease
Succinyl CoA (Succinyl-coenzyme A) is a pivotal intermediate metabolite in the tricarboxylic acid cycle and a key coenzyme A metabolite. Succinyl CoA is biosynthesized from α-ketoglutarate or propionyl-CoA. Succinyl CoA acts as a critical precursor and substrate for heme biosynthesis and gluconeogenesis. Succinyl CoA insufficiency caused by cobalamin deficiency is directly linked to growth retardation, impaired heme synthesis, tissue glycine accumulation and neurological abnormalities. Succinyl CoA can be used in research on metabolic, neurological, and hematological abnormalities (such as porphyria) caused by nutritional vitamin B12 deficiency (leading to a lack of Succinyl-Coenzyme A synthesis) .

HY-W015883S1

Fumaric acid-13C2	Isotope-Labeled Compounds Endogenous Metabolite NF-κB p38 MAPK	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Fumaric acid- ¹³C₂ is the ¹³C-labeled Fumaric acid (HY-W015883). Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension .

HY-128851R

Coenzyme A (Standard)	Reference Standards Fatty Acid Synthase (FASN) Endogenous Metabolite	Metabolic Disease Cancer
Coenzyme A (Standard) is the analytical standard of Coenzyme A. This product is intended for research and analytical applications. Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids[1].

HY-W010382R

Oxaloacetic acid (Standard) 2 Publications Verification 2-Oxosuccinic acid (Standard)	Reference Standards Endogenous Metabolite Reactive Oxygen Species (ROS)	Metabolic Disease
Oxaloacetic acid (Standard) is the analytical standard of Oxaloacetic acid. This product is intended for research and analytical applications. Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis, whereby Oxaloacetic acid facilitates the clearance of reactive oxygen species (ROS) and improves mitochondrial function .

HY-W015883R

Fumaric acid (Standard)	Reference Standards Endogenous Metabolite NF-κB p38 MAPK	Metabolic Disease Inflammation/Immunology
Fumaric acid (Standard) is the analytical standard of Fumaric acid. This product is intended for research and analytical applications. Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension .

HY-P2993

Isocitrate dehydrogenase, Porcine heart ICDH; IDH	Isocitrate Dehydrogenase (IDH)	Metabolic Disease Cancer
Isocitrate dehydrogenase, Porcine heart (ICDH) is a citric acid or tricarboxylic acid cycle enzyme, is often used in biochemical studies. Isocitrate dehydrogenase catalyzes the oxidative decarboxylation of isocitrate to α-ketoglutarate and reduces NAD(P) ⁺ to NAD(P)H, it plays important roles in cellular metabolism .

HY-W009362R

DL-Isocitric acid trisodium salt (Standard)	Reference Standards Endogenous Metabolite	Others
DL-Isocitric acid (trisodium salt) (Standard) is the analytical standard of DL-Isocitric acid (trisodium salt). This product is intended for research and analytical applications. DL-Isocitric acid trisodium salt is an endogenous metabolite. DL-Isocitric acid trisodium salt is an intermediate product in the citric acid cycle. DL-Isocitric acid trisodium salt can be used as a marker for determining the composition of isocitrates in fruit products.

HY-N1428S2

Citric acid-13C2	Isotope-Labeled Compounds Apoptosis Endogenous Metabolite Bacterial	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Citric acid- ¹³C₂ is the ¹³C-labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-N1428S6

Citric acid-d4-1	Isotope-Labeled Compounds Endogenous Metabolite Apoptosis Bacterial	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Citric acid-d₄-1 is deuterated labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-W127841

Citric acid-2,4-13C2	Isotope-Labeled Compounds Apoptosis Endogenous Metabolite Bacterial	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Citric acid-2,4- ¹³C₂ is the ¹³C-labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-N1428AR

Citric acid monohydrate (Standard)	Reference Standards Endogenous Metabolite Apoptosis Bacterial	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Citric acid monohydrate (Standard) is the analytical standard of Citric acid monohydrate (HY-N1428A). This product is intended for research and analytical applications. Citric acid monohydrate is a natural preservative and food tartness enhancer. Citric acid monohydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid monohydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid monohydrate is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-P2993A

Isocitrate dehydrogenase, Microorganism ICDH, Microorganism; IDH, Microorganism	Isocitrate Dehydrogenase (IDH)	Metabolic Disease
Isocitrate dehydrogenase, Microorganism (IDH) (EC 1.1.1.42) is a citric acid or tricarboxylic acid cycle enzyme, is often used in biochemical studies. Isocitrate dehydrogenase catalyzes the oxidative decarboxylation of isocitrate to α-ketoglutarate and reduces NAD(P) ⁺ to NAD(P)H, it plays important roles in cellular metabolism .

HY-W009362S

DL-Isocitric acid-13C4 trisodium salt	Isotope-Labeled Compounds Endogenous Metabolite	Others
DL-Isocitric acid- ¹³C₄ (trisodium salt) is a ¹³C labeled DL-Isocitric acid (trisodium salt) (HY-W009362). DL-Isocitric acid trisodium salt is an endogenous metabolite. DL-Isocitric acid trisodium salt is a substrate in the citric acid cycle. DL-Isocitric acid trisodium salt can be used as a marker for determining the composition of isocitrates in fruit products, including fruit juices.

HY-13451R

Finafloxacin (Standard)	Reference Standards Bacterial Antibiotic	Infection
Citric acid (Standard) is the analytical standard of Citric acid. This product is intended for research and analytical applications. Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice .

HY-W009156R

Citric acid tripotassium hydrate (Standard) Potassium citrate monohydrate (Standard)	Reference Standards Apoptosis Endogenous Metabolite Bacterial	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Citric acid tripotassium hydrate (Standard) (Potassium citrate monohydrate (Standard)) is the analytical standard of Citric acid tripotassium hydrate (HY-W009156). This product is intended for research and analytical applications. Citric acid tripotassium hydrate is a natural preservative and food tartness enhancer. Citric acid tripotassium hydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid tripotassium hydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid tripotassium hydrate is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-N15821

30:0 Coenzyme A ammonium	Endogenous Metabolite	Metabolic Disease
30:0 Coenzyme A ammonium is a vital cofactor in various metabolic processes, particularly in the citric acid cycle and fatty acid metabolism .

HY-W017524R

2-Methylpentanedioic acid (Standard)	Reference Standards Endogenous Metabolite	Others
2-Methylpentanedioic acid (Standard) is the analytical standard of 2-Methylpentanedioic acid. This product is intended for research and analytical applications. 2-Methylpentanedioic acid is a metabolite of succinic acid, a citric acid cycle intermediate.

HY-134098R

Diisopropyl adipate (Standard) Adipic acid diisopropyl ester (Standard)	TRP Channel Reference Standards	Others
Oxaloacetic acid (Standard) is the analytical standard of Oxaloacetic acid. This product is intended for research and analytical applications. Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis, whereby Oxaloacetic acid facilitates the clearance of reactive oxygen species (ROS) and improves mitochondrial function .

HY-W693142

Succinate calcium	Orphan GPCR Apoptosis	Cardiovascular Disease
Succinate calcium is a key intermediate product of the citric acid cycle (tricarboxylic acid cycle). Succinate calcium can act as a specific ligand for the G protein-coupled receptor GPR91. Succinate calcium can increase the amplitude of calcium transient in cardiac muscle cells and accelerate the decay rate of calcium transient. Succinate calcium can induce myocardial apoptosis .

HY-Y1311G

Malic acid Hydroxybutanedioic acid; E 296	Endogenous Metabolite	Others
Malic acid (GMP) is Malic acid (HY-Y1311) in GMP grade. GMP-grade small molecules can be used as auxiliary reagents in cell therapy. Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that occurs naturally in fruits like apples and pears with oral activities. Malic acid plays a role in many sour or tangy foods. Malic acid is an intermediate in the citric acid cycle .

HY-W020215R

Tricarballylic acid (Standard)	Reference Standards Mitochondrial Metabolism Endogenous Metabolite	Metabolic Disease
Tricarballylic acid (Standard) is the analytical standard of Tricarballylic acid (HY-W020215). This product is intended for research and analytical applications. Tricarballylic acid is an orally active compound that can be produced by rumen microorganisms and has the activity of chelating magnesium. Tricarballylic acid is also a competitive inhibitor of aconitate hydratase, with a K_i value of 0.52 mM. Tricarballylic acid can inhibit the oxidation of acetate in the citric acid cycle and can be used in the research of ruminant tissue metabolism and grass tetany syndrome. In addition, Tricarballylic acid can be used to synthesize specific complexes and produce plasticizers .

HY-W724319

Citric acid-d4 trisodium Sodium citrate-d₄; Trisodium citrate anhydrous-d₄	Isotope-Labeled Compounds Apoptosis Bacterial Endogenous Metabolite	Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology Cancer
Citric acid-d₄ trisodium (Sodium citrate-d₄) is the deuterium labeled Citric acid trisodium (HY-B2201). Citric acid trisodium (Sodium citrate) is a natural preservative and food tartness enhancer. Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid trisodium cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid trisodium is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-P2934A

α-Ketoglutarate Dehydrogenase, Porcine	Endogenous Metabolite	Metabolic Disease
α-Ketoglutarate dehydrogenase, Porcine (EC 1.2.4.2) is an enzyme complex that functions in the citric acid cycle.

HY-P2994B

3-Hydroxybutyrate Dehydrogenase, Alcaligenes faecalis	Endogenous Metabolite	Metabolic Disease
3-Hydroxybutyrate Dehydrogenase, Alcaligenes faecalis (EC 1.1.1.30) catalyzes the oxidation of 3-hydroxybutyrate to acetoacetate, the first step in the conversion of ketone bodies to citric acid, which is then further metabolized via the tricarboxylic acid cycle (Krebs cycle).

HY-P3001A

Malate Dehydrogenase,Yeast	Malate Dehydrogenase (MDH)	Metabolic Disease
Malate dehydrogenase, Yeast (EC 1.1.1.37) is an enzyme in the citric acid cycle that catalyzes the conversion of malate to oxaloacetate (requiring NAD+). Malate dehydrogenase participates in gluconeogenesis, the process of synthesizing glucose from small molecules.

HY-P3001C

Malate dehydrogenase, Bacteria	Biochemical Assay Reagents	Metabolic Disease
Malate dehydrogenase, Bacteria (EC 1.1.1.37), is an enzyme in the citric acid cycle that catalyzes the conversion of malate to oxaloacetate (requiring NAD+). Malate dehydrogenase also participates in gluconeogenesis, the process of synthesizing glucose from small molecules.

HY-E71013

Nucleoside monophosphate kinase, Bovine	Endogenous Metabolite	Metabolic Disease
Nucleoside monophosphate kinase, Bovine (EC 2.7.4.6) is an enzymes that catalyze the exchange of phosphate groups between different nucleoside diphosphates. Nucleoside monophosphate kinase, Bovine (EC 2.7.4.6) activities maintain an equilibrium between the concentrations of different nucleoside triphosphates such as, for example, when GTP produced in the citric acid (Krebs) cycle is converted to ATP.

Cat. No.	Product Name

HY-L148

TCA Cycle Compound Library

72 compounds

The TCA cycle (tricarboxylic acid cycle)—is also known as the Krebs cycle or the citric acid cycle (CAC). The TCA cycle is a series of chemical reactions that release stored energy through the oxidation of acetyl-CoA in carbohydrates, fats, and proteins.

For decades, the TCA cycle has been considered as the central pathway for cell oxidative phosphorylation to produce energy and biosynthesis. Research shows that TCA cycle is associated with many diseases, especially cancer. In colon carcinoma, liver cancer and other cancers, there are mutations that lead to the imbalance of TCA cycle metabolites, indicating that TCA cycle may be related to the occurrence of cancer. Understanding the role and molecular mechanism of TCA cycle in inhibiting or promoting cancer progression will promote the development of new metabolite-based cancer treatment methods in the future.

MCE supplies a unique collection of 72 compounds related to the TCA cycle. MCE TCA Cycle Compound Library is a useful tool for the TCA cycle related research and anti-cancer drug development.

HY-L231

TCA Cycle Metabolite Compound Library

26 compounds

MCE supplies a unique collection of 26 key intermediates of the TCA cycle, which can be utilized for TCA-related research and metabolomics identification studies.

HY-L182

Fatty Acids Compound Library

285 compounds

Fatty acids (FAs) are the main components of lipids. The synthesis of fatty acids mainly involves the Triglyceride (TG) cycle and De Novo Lipogenesis (DNL). Fatty acids which exist widely in organisms are components of cell membranes and play an indispensable role in cell signaling. In addition, FFAs can be taken up from circulating plasma by all mitochondria-containing cells, and they are metabolized by β-oxidation and the citric acid cycle to release large amounts of energy in the form of ATP. Abnormal fatty acid metabolism is associated with the occurrence and development of cardiovascular diseases, diabetes, fatty liver, hyperthyroidism, and other diseases.

MCE offers a unique collection of fatty acid compounds. Fatty Acids Compound Library is an important tool for the study of energy metabolism and drug development of metabolism-related diseases.

Cat. No.	Product Name	Type

HY-B2201

Citric acid trisodium

Maximum Cited Publications

11 Publications Verification

Sodium citrate; Trisodium citrate anhydrous

Biochemical Assay Reagents

Citric acid trisodium (Sodium citrate) is a natural preservative and food tartness enhancer. Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid trisodium cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid trisodium is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-128851B

Coenzyme A sodium 2 Publications Verification	Biochemical Assay Reagents
Coenzyme A (CoASH) sodium is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .

HY-N1428A

Citric acid monohydrate

5+ Cited Publications

Biochemical Assay Reagents

Citric acid monohydrate is a natural preservative and food tartness enhancer. Citric acid monohydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid monohydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid monohydrate is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-128851A

Coenzyme A trilithium 2 Publications Verification	Biochemical Assay Reagents
Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .

HY-W015883A

Fumaric acid disodium 4 Publications Verification	Biochemical Assay Reagents
Fumaric acid disodium is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid disodium exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid disodium can be used in the study of pregnancy-induced hypertension .

HY-W008606

Sodium citrate monobasic

citric acid monosodium salt

Biochemical Assay Reagents

Sodium citrate monobasic (Citric acid monosodium salt) is a natural preservative and food tartness enhancer. Sodium citrate monobasic induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Sodium citrate monobasic cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Sodium citrate monobasic is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-W127841

Citric acid-2,4-13C2

Biochemical Assay Reagents

Citric acid-2,4- ¹³C₂ is the ¹³C-labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-N1428AR

Citric acid monohydrate (Standard)

Biochemical Assay Reagents

Citric acid monohydrate (Standard) is the analytical standard of Citric acid monohydrate (HY-N1428A). This product is intended for research and analytical applications. Citric acid monohydrate is a natural preservative and food tartness enhancer. Citric acid monohydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid monohydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid monohydrate is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-Y1311G

Malic acid Hydroxybutanedioic acid; E 296	Biochemical Assay Reagents
Malic acid (GMP) is Malic acid (HY-Y1311) in GMP grade. GMP-grade small molecules can be used as auxiliary reagents in cell therapy. Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that occurs naturally in fruits like apples and pears with oral activities. Malic acid plays a role in many sour or tangy foods. Malic acid is an intermediate in the citric acid cycle .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-128851

Coenzyme A 2 Publications Verification	Natural Products Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Endogenous Metabolite Fatty Acid Synthase (FASN)
Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .

HY-N1428

Citric acid Maximum Cited Publications 34 Publications Verification	Cardiovascular Disease Structural Classification Preservatives Classification of Application Fields Anti-aging Endocrine diseases Metabolic Disease Endogenous metabolite Food Research Infection Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Inflammation/Immunology Disease Research Fields Cancer Source Classification	Environmental Pollutants Endogenous Metabolite Bacterial Apoptosis
Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-W015883

Fumaric acid 4 Publications Verification	Structural Classification Classification of Application Fields Endocrine diseases Metabolic Disease Endogenous metabolite Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Disease Research Fields Cancer Source Classification	Environmental Pollutants Endogenous Metabolite NF-κB p38 MAPK
Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension .

HY-Y1311

Malic acid 4 Publications Verification Hydroxybutanedioic acid; E 296	Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Ketones, Aldehydes, Acids Malus pumila Mill. Rosaceae Other Diseases Plants Endogenous metabolite Disease Research Fields Source Classification	Environmental Pollutants Endogenous Metabolite
Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that occurs naturally in fruits like apples and pears with oral activities. Malic acid plays a role in many sour or tangy foods. Malic acid is an intermediate in the citric acid cycle .

HY-W009362

DL-Isocitric acid trisodium salt 2 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
DL-Isocitric acid trisodium salt is an endogenous metabolite. DL-Isocitric acid trisodium salt is an intermediate product in the citric acid cycle. DL-Isocitric acid trisodium salt can be used as a marker for determining the composition of isocitrates in fruit products .

HY-137808

Succinyl-Coenzyme A sodium 3 Publications Verification Succinyl-CoA sodium	Structural Classification Natural Products Neurological Disease Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Succinyl CoA (Succinyl-coenzyme A) sodium is a pivotal intermediate metabolite in the tricarboxylic acid cycle and a key coenzyme A metabolite. Succinyl CoA sodium is biosynthesized from α-ketoglutarate or propionyl-CoA. Succinyl CoA sodium acts as a critical precursor and substrate for heme biosynthesis and gluconeogenesis. Succinyl CoA sodium insufficiency caused by cobalamin deficiency is directly linked to growth retardation, impaired heme synthesis, tissue glycine accumulation and neurological abnormalities. Succinyl CoA sodium can be used in research on metabolic, neurological, and hematological abnormalities (such as porphyria) caused by nutritional vitamin B12 deficiency (leading to a lack of Succinyl-Coenzyme A synthesis) .

HY-W010382

Oxaloacetic acid 2 Publications Verification 2-Oxosuccinic acid	Human Gut Microbiota Metabolites Microorganisms Other disease Classification of Application Fields Anti-aging Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Reactive Oxygen Species (ROS)
Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis, whereby Oxaloacetic acid facilitates the clearance of reactive oxygen species (ROS) and improves mitochondrial function .

HY-W009156

Citric acid tripotassium hydrate 10+ Cited Publications Potassium citrate monohydrate	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Guttiferae Metabolic Disease Plants Garcinia cambogia Inflammation/Immunology Disease Research Fields	Environmental Pollutants Endogenous Metabolite Bacterial Apoptosis
Citric acid tripotassium hydrate (Potassium citrate monohydrate) is a natural preservative and food tartness enhancer. Citric acid tripotassium hydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid tripotassium hydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid tripotassium hydrate is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-W015883A

Fumaric acid disodium 4 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite NF-κB p38 MAPK
Fumaric acid disodium is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid disodium exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid disodium can be used in the study of pregnancy-induced hypertension .

HY-W020215

Tricarballylic acid 1 Publications Verification	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Mitochondrial Metabolism Endogenous Metabolite
Tricarballylic acid is an orally active compound that can be produced by rumen microorganisms and has the activity of chelating magnesium. Tricarballylic acid is also a competitive inhibitor of aconitate hydratase, with a K_i value of 0.52 mM. Tricarballylic acid can inhibit the oxidation of acetate in the citric acid cycle and can be used in the research of ruminant tissue metabolism and grass tetany syndrome. In addition, Tricarballylic acid can be used to synthesize specific complexes and produce plasticizers .

HY-N1428R

Citric acid (standard) 5+ Cited Publications	Structural Classification Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Cancer Source Classification	Reference Standards Apoptosis Endogenous Metabolite Bacterial
Citric acid (Standard) is the analytical standard of Citric acid (HY-N1428). This product is intended for research and analytical applications. Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-W017524

2-Methylpentanedioic acid 1 Publications Verification	Immune System Disorder Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
2-Methylpentanedioic acid is a metabolite of succinic acid, a citric acid cycle intermediate.

HY-148285

Succinyl CoA Succinyl-coenzyme A; S-(Hydrogen succinyl)coenzyme A	Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Endogenous Metabolite
Succinyl CoA (Succinyl-coenzyme A) is a pivotal intermediate metabolite in the tricarboxylic acid cycle and a key coenzyme A metabolite. Succinyl CoA is biosynthesized from α-ketoglutarate or propionyl-CoA. Succinyl CoA acts as a critical precursor and substrate for heme biosynthesis and gluconeogenesis. Succinyl CoA insufficiency caused by cobalamin deficiency is directly linked to growth retardation, impaired heme synthesis, tissue glycine accumulation and neurological abnormalities. Succinyl CoA can be used in research on metabolic, neurological, and hematological abnormalities (such as porphyria) caused by nutritional vitamin B12 deficiency (leading to a lack of Succinyl-Coenzyme A synthesis) .

HY-128851R

Coenzyme A (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Reference Standards Fatty Acid Synthase (FASN) Endogenous Metabolite
Coenzyme A (Standard) is the analytical standard of Coenzyme A. This product is intended for research and analytical applications. Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids[1].

HY-W010382R

Oxaloacetic acid (Standard) 2 Publications Verification 2-Oxosuccinic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Other disease Ketones, Aldehydes, Acids Disease markers Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Reactive Oxygen Species (ROS)
Oxaloacetic acid (Standard) is the analytical standard of Oxaloacetic acid. This product is intended for research and analytical applications. Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis, whereby Oxaloacetic acid facilitates the clearance of reactive oxygen species (ROS) and improves mitochondrial function .

HY-W015883R

Fumaric acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Cancer Source Classification	Reference Standards Endogenous Metabolite NF-κB p38 MAPK
Fumaric acid (Standard) is the analytical standard of Fumaric acid. This product is intended for research and analytical applications. Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension .

HY-W009362R

DL-Isocitric acid trisodium salt (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
DL-Isocitric acid (trisodium salt) (Standard) is the analytical standard of DL-Isocitric acid (trisodium salt). This product is intended for research and analytical applications. DL-Isocitric acid trisodium salt is an endogenous metabolite. DL-Isocitric acid trisodium salt is an intermediate product in the citric acid cycle. DL-Isocitric acid trisodium salt can be used as a marker for determining the composition of isocitrates in fruit products.

HY-13451R

Finafloxacin (Standard)	Microorganisms Source Classification	Reference Standards Bacterial Antibiotic
Citric acid (Standard) is the analytical standard of Citric acid. This product is intended for research and analytical applications. Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice .

HY-W009156R

Citric acid tripotassium hydrate (Standard) Potassium citrate monohydrate (Standard)	Structural Classification Ketones, Aldehydes, Acids Guttiferae Plants Garcinia cambogia	Reference Standards Apoptosis Endogenous Metabolite Bacterial
Citric acid tripotassium hydrate (Standard) (Potassium citrate monohydrate (Standard)) is the analytical standard of Citric acid tripotassium hydrate (HY-W009156). This product is intended for research and analytical applications. Citric acid tripotassium hydrate is a natural preservative and food tartness enhancer. Citric acid tripotassium hydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid tripotassium hydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid tripotassium hydrate is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-N15821

30:0 Coenzyme A ammonium	Lipid	Endogenous Metabolite
30:0 Coenzyme A ammonium is a vital cofactor in various metabolic processes, particularly in the citric acid cycle and fatty acid metabolism .

HY-W017524R

2-Methylpentanedioic acid (Standard)	Structural Classification Immune System Disorder Ketones, Aldehydes, Acids Disease markers Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
2-Methylpentanedioic acid (Standard) is the analytical standard of 2-Methylpentanedioic acid. This product is intended for research and analytical applications. 2-Methylpentanedioic acid is a metabolite of succinic acid, a citric acid cycle intermediate.

HY-W020215R

Tricarballylic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Mitochondrial Metabolism Endogenous Metabolite
Tricarballylic acid (Standard) is the analytical standard of Tricarballylic acid (HY-W020215). This product is intended for research and analytical applications. Tricarballylic acid is an orally active compound that can be produced by rumen microorganisms and has the activity of chelating magnesium. Tricarballylic acid is also a competitive inhibitor of aconitate hydratase, with a K_i value of 0.52 mM. Tricarballylic acid can inhibit the oxidation of acetate in the citric acid cycle and can be used in the research of ruminant tissue metabolism and grass tetany syndrome. In addition, Tricarballylic acid can be used to synthesize specific complexes and produce plasticizers .

Cat. No.	Product Name	Chemical Structure

HY-N1428S1

Citric acid-13C6

Citric acid- ¹³C₆ is the ¹³C-labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-N1428S

Citric acid-d4

Citric acid-d₄ is the deuterium labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-N1428S3

Citric acid-13C3

Citric acid- ¹³C₃ is the ¹³C-labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-W010382S

Oxaloacetic acid-13C4 1 Publications Verification
Oxaloacetic acid- ¹³C₄ is the ¹³C-labeled Oxaloacetic acid. Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis .

HY-W015883S1

Fumaric acid-13C2

Fumaric acid- ¹³C₂ is the ¹³C-labeled Fumaric acid (HY-W015883). Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension .

HY-N1428S2

Citric acid-13C2

Citric acid- ¹³C₂ is the ¹³C-labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-N1428S6

Citric acid-d4-1

Citric acid-d₄-1 is deuterated labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

HY-W127841

Citric acid-2,4-13C2

HY-W009362S

DL-Isocitric acid-13C4 trisodium salt
DL-Isocitric acid- ¹³C₄ (trisodium salt) is a ¹³C labeled DL-Isocitric acid (trisodium salt) (HY-W009362). DL-Isocitric acid trisodium salt is an endogenous metabolite. DL-Isocitric acid trisodium salt is a substrate in the citric acid cycle. DL-Isocitric acid trisodium salt can be used as a marker for determining the composition of isocitrates in fruit products, including fruit juices.

HY-W724319

Citric acid-d4 trisodium

Citric acid-d₄ trisodium (Sodium citrate-d₄) is the deuterium labeled Citric acid trisodium (HY-B2201). Citric acid trisodium (Sodium citrate) is a natural preservative and food tartness enhancer. Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid trisodium cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid trisodium is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y1311G

Malic acid Hydroxybutanedioic acid; E 296	Endogenous Metabolite	Others
Malic acid (GMP) is Malic acid (HY-Y1311) in GMP grade. GMP-grade small molecules can be used as auxiliary reagents in cell therapy. Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that occurs naturally in fruits like apples and pears with oral activities. Malic acid plays a role in many sour or tangy foods. Malic acid is an intermediate in the citric acid cycle .

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citric acid cycle

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