Oxaloacetic acid-13C4
Based on 1 publication(s) in Google Scholar
Oxaloacetic acid-13C4 is the 13C-labeled Oxaloacetic acid. Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis.
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- Purity: 99.23%
- CAS No.: 161096-82-8
- 화학식: 13C4H4O5
- 분자량:136.04
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보관:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Oxaloacetic acid-13C4
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[3]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 161096-82-8
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Unlabeled Cas 328-42-7
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Appearance Solid
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분자량 136.04
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화학식 13C4H4O5
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Color White to off-white
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SMILES
O[13C]([13CH2][13C]([13C](O)=O)=O)=O
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Synonyms
2-Oxosuccinic acid-13C4
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (1)
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Journal Impact Factor
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Most Recent
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Nat Microbiol
Oxaloacetate sensing promotes innate immune antiviral defence against influenza virus infection. [Abstract]2025 Oct;10(10):2521-2536. PMID: 40983701
용액&용해도
Ethanol : ≥ 15 mg/mL (110.26 mM)
DMF : ≥ 15 mg/mL (110.26 mM)
DMSO : ≥ 15 mg/mL (110.26 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. F. L. Breusch. The fate of oxaloacetic acid in different organs. Biochem J. 1939 Nov; 33(11): 1757-1770. [Content Brief]
[2]. Brian D Fink, et al. Oxaloacetic acid mediates ADP-dependent inhibition of mitochondrial complex II-driven respiration. J Biol Chem. 2018 Dec 21;293(51):19932-19941. [Content Brief]
[3]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol / DMF / DMSO | 1 mM | 7.3508 mL | 36.7539 mL | 73.5078 mL | 183.7695 mL |
| 5 mM | 1.4702 mL | 7.3508 mL | 14.7016 mL | 36.7539 mL | |
| 10 mM | 0.7351 mL | 3.6754 mL | 7.3508 mL | 18.3769 mL | |
| 15 mM | 0.4901 mL | 2.4503 mL | 4.9005 mL | 12.2513 mL | |
| 20 mM | 0.3675 mL | 1.8377 mL | 3.6754 mL | 9.1885 mL | |
| 25 mM | 0.2940 mL | 1.4702 mL | 2.9403 mL | 7.3508 mL | |
| 30 mM | 0.2450 mL | 1.2251 mL | 2.4503 mL | 6.1256 mL | |
| 40 mM | 0.1838 mL | 0.9188 mL | 1.8377 mL | 4.5942 mL | |
| 50 mM | 0.1470 mL | 0.7351 mL | 1.4702 mL | 3.6754 mL | |
| 60 mM | 0.1225 mL | 0.6126 mL | 1.2251 mL | 3.0628 mL | |
| 80 mM | 0.0919 mL | 0.4594 mL | 0.9188 mL | 2.2971 mL | |
| 100 mM | 0.0735 mL | 0.3675 mL | 0.7351 mL | 1.8377 mL |
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