Search Result
Results for "
nitro
" in MedChemExpress (MCE) Product Catalog:
13
Biochemical Assay Reagents
6
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-15925
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NBT
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Fluorescent Dye
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Others
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Nitro blue tetrazolium chloride (NBT) is a substrate for dehydrogenases; is used with the alkaline phosphatase substrate 5-Bromo-4-Chloro-3-Indolyl Phosphate (BCIP) in western blotting and immunohistological staining procedures .
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-
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- HY-B1159
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8-Hydroxy-5-nitroquinoline; 5-nitro-8-quinolinol
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Bacterial
Antibiotic
Apoptosis
Autophagy
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Infection
Cancer
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Nitroxoline (8-Hydroxy-5-nitroquinoline), an antibiotic, is an orally active antibiofilm agent. Nitroxoline reduces the formation and induces the dispersal of Pseudomonas aeruginosa biofilms by chelation of iron and zinc. Nitroxoline can be used for the urinary tract infections and cancer research .
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- HY-128896
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- HY-139824
-
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Others
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Cancer
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Nitro-coronene can be used to prepare near-infrared light-triggered lysosome-targetable carbon dots for photothermal research of cancer.
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- HY-157917
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Biochemical Assay Reagents
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Others
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Nitro-PAPS disodium dihydrate is a highly sensitive colometric reagent for Fe(II) detection with a maximal absorption wavelength of 592 nm. Nitro-PAPS disodium dihydrate is suitable for the determination of Fe(II) in serum and also be used to determine micro molar levels of Cu, Zn, Ni, Co and V .
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- HY-B0226
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nitrofural
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Bacterial
Antibiotic
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Infection
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Nitrofurazone (Nitrofural) is a broad spectrum antibiotic that has oral activity. Nitrofurazone is a nitro-aromatic drug. Nitrofurazone is active against both Gram-positive and Gram-negative bacteria .
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- HY-B1159S
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8-Hydroxy-5-nitroquinoline-d4; 5-nitro-8-quinolinol-d4
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Bacterial
Autophagy
Antibiotic
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Infection
Cancer
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Nitroxoline-d4 is the deuterium labeled Nitroxoline. Nitroxoline is an antibiotic that has proven to be very effective at combating biofilm infections. Nitroxoline functions by chelating Fe2+ and Zn2+ ions from the biofilm matrix[1][2].
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- HY-123823
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NCX 4016
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COX
Apoptosis
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Cancer
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Nitroaspirin (NCX 4016) is a nitric oxide (NO) donor and a nitro-derivative of Aspirin, which combines with Nitroaspirin to inhibit cyclooxygenase. Nitroaspirin (NCX 4016) has antithrombotic and anti-platelet properties and acts as a direct and irreversible inhibitor of COX-1. Nitroaspirin (NCX 4016) causes significant induction of cell cycle arrest and apoptosis in Cisplatin-resistant human ovarian cancer cells via down-regulation of EGFR/PI3K/STAT3 signaling and modulation of Bcl-2 family proteins .
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- HY-P4561
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Cathepsin
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Others
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H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide that can serve as a substrate for cathepsin D, pepsin and pepsinogen. H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH has potential applications in biochemical analysis .
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- HY-P4556
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Biochemical Assay Reagents
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Others
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H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is a polypeptide that can be hydrolyzed by Rennin (HY-P2810). H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is commonly used as a biochemical reaction reagent .
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- HY-D1637
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Fluorescent Dye
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Others
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5-Nitro BAPTA tetramethyl ester is a calcium chelator. 5-Nitro BAPTA tetramethyl ester involves in the two-photon probe synthesis, and is used for real-time imaging of intracellular calcium ions, calcium waves monitoring at a depth of 100-300 μm in liver tissues for 1100-4000 s. 5-Nitro BAPTA tetramethyl ester, together with fluorescent compound 2-Me-substituted TM, can be used to form a red fluorescent probe (CaTM-2 AM) .
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- HY-D1636
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Fluorescent Dye
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Others
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5-Nitro BAPTA is a calcium chelator, combinded with 2-Me-substituted TM ( as a fluorescent moiety), can be used to form a red fluorescent probe (CaTM-2 AM), for imaging of cytoplasmic Ca 2+ in cultured living cells. 5-Nitro BAPTA is a building block used in the synthesis of Ca 2+ specific chelators, Ca 2+ buffers, and fluorescent Ca 2+ indicators .
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- HY-W014340S
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- HY-137541
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NTCB
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Biochemical Assay Reagents
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Others
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2-Nitro-5-thiocyanatobenzoic acid (NTCB) is a highly reactive reagent that transfers its cyano group rapidly to a nucleophilic thiolate. 2-Nitro-5-thiocyanatobenzoic acid has been proposed as a reagent for converting thiol groups in proteins into their S-cyano derivatives .
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- HY-113248S
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Endogenous Metabolite
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Metabolic Disease
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3-Nitro-L-tyrosine-d3 is the deuterium labeled 3-Nitro-L-tyrosine. 3-Nitro-L-tyrosine is a biomarker of nitrogen free radical species modified proteins in systemic autoimmunogenic conditions[1][2].
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- HY-W014626
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Biochemical Assay Reagents
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Others
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4-Nitro-3-(trifluoromethyl)aniline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-130437
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MDM-2/p53
TGF-β Receptor
Caspase
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Infection
Metabolic Disease
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p-nitro-Pifithrin-α, a cell-permeable analog of pifithrin-α, is a potent p53 inhibitor. p-nitro-Pifithrin-α suppresses p53-mediated TGF-β1 expression in HK-2 cells. p-nitro-Pifithrin-α inhibits the activation of caspase-3 by Zika virus (ZIKV) strains. p-nitro-Pifithrin-α attenuates steatosis and liver injury in mice fed a high-fat diet [4].
non-alcoholic fatty liver disease .
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- HY-W004570
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5-NP
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Endogenous Metabolite
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Infection
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5-Nitro-1,10-phenanthroline (5-NP), is a o-Phenanthroline (HY-W004544) derivative, as a mediator of glucose oxidase (GOX) with antituberculous activity. 5-Nitro-1,10-phenanthroline can be applied as redox mediators for oxidases and is suitable for the development of reagent-less biosensors and biofuel cells .
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- HY-113248S1
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Endogenous Metabolite
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Metabolic Disease
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3-Nitro-L-tyrosine- 13C6 is the 13C labeled 3-Nitro-L-tyrosine[1]. 3-Nitro-L-tyrosine is a biomarker of nitrogen free radical species modified proteins in systemic autoimmunogenic conditions[2].
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- HY-W014316
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Bacterial
Fungal
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Infection
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5-Bromo-5-nitro-1,3-dioxane, an antimicrobial compound, is effective against Gram-positive and Gram-negative bacteria and fungi, including yeast. 5-Bromo-5-nitro-1,3-dioxane inhibits enzyme activity and subsequent inhibition of microbial growth by the oxidation of essential protein thiol .
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- HY-W142003
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- HY-W002416
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- HY-123076
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PFN-α
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MDM-2/p53
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Neurological Disease
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Pifithrin-α, p-Nitro, Cyclic (PFN-α) is cell-permeable and active-form p53 inhibitor. Pifithrin-α, p-Nitro, Cyclic is one order magnitude more active than Pifithrin-α in protecting cortical neurons exposed to Etoposide (ED50=30 nM). Pifithrin-α, p-Nitro, Cyclic behaves as a p53 posttranscriptional activity inhibitor. Pifithrin-α, p-Nitro, Cyclic do not prevent p53 phosphorylation on the S15 residue .
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- HY-W014049
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NO Synthase
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Others
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N'-Nitro-D-arginine, a nitric oxide synthesis inhibitor, also is a vasodilator that relaxes the smooth muscles and increases blood flow to the penis, improving erections. N'-Nitro-D-arginine also inhibits neutrophil migration by blocking receptors for tumour necrosis factor alpha (TNFα) and interleukin 8 (IL8) .
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- HY-113248
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- HY-75379
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-
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- HY-P4546
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- HY-116108
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Musk tibetine
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Others
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Cancer
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Musk tibetene (Musk tibetine) is a nitro musk compound with carcinogenic activity. Musk tibetine reveals no genotoxicity in the micronucleus test with human lymphocytes and human hepatoma cell line .
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- HY-W273413
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NBD-H
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Fluorescent Dye
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Cancer
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4-Hydrazino-7-nitro-benzofurazan hydrazine adduct is a fluorescent reagent for protein labeling.
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- HY-W002060
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2-Amino-5-nitro-4-picoline
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Biochemical Assay Reagents
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Others
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4-Methyl-5-nitropyridin-2-amine (2-Amino-5-nitro-4-picoline) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-P4466
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HIV Protease
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Infection
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Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 is a fluorogenic substrate of HIV-1 protease. Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 can be used to test HIV-1 protease activity .
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- HY-154146
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Nucleoside Antimetabolite/Analog
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Cancer
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5-Nitro-1-(3-azido-3-deoxy-β-D-ribofuranosyl)-2(1H)-pyridinone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 5-Nitro-1-(3-azido-3-deoxy-β-D-ribofuranosyl)-2(1H)-pyridinone is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-W556327
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Nucleoside Antimetabolite/Analog
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Cancer
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5-Nitro-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyridinone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-101559
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CXA-10
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Others
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Inflammation/Immunology
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10-Nitrooleic acid (CXA-10), a nitro fatty acid, has potential effects in disease states in which oxidative stress, inflammation, fibrosis, and/or direct tissue toxicity play significant roles .
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- HY-W016450
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Biochemical Assay Reagents
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Others
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2-Nitro-5-methylbenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W001576
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Biochemical Assay Reagents
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Others
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6-Nitro-1H-indole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W002458
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Biochemical Assay Reagents
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Others
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4-Nitro-1H-pyrazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-123538
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-
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- HY-136998
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Biochemical Assay Reagents
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Others
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10-Nitrooleate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W179417
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- HY-13543
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CB 1954
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DNA Alkylator/Crosslinker
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Cancer
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Tretazicar (CB 1954), an antitumor proagent, is highly selective against the Walker 256 rat tumour line. Tretazicar is enzymatically activated to generate a bifunctional agent, which can form DNA-DNA interstrand cross-links. Tretazicar in rat cells involves the reduction of its 4-nitro group to a 4-hydroxylamine by the enzyme NAD(P)H:quinone oxidoreductase 1 (NQO1) .
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- HY-12690
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Others
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Cancer
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DOTA derivative is a benxyl derivative of the cyclic tosamide; can be nitrated directly; is more convenient to incorporate the nitro group after deprotection lithium aluminum hydride.
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- HY-12692
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DO3A tert-butyl; DO3A-t-Bu-ester
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Others
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Others
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DOTA tert-Butyl ester is a benxyl derivative of the cyclic tosamide; can be nitrated directly; is more convenient to incorporate the nitro group after deprotection lithium aluminum hydride.
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- HY-N7040
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HSV
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Infection
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11-Deoxymogroside IIE is a cucurbitane glycoside, isolated from Siraitia grosvenorii fruits.
11-Deoxymogroside IIE has inhibitory effect against Epstein Barr virus (EBV-EA) activation induced by TPA, shows weak inhibitory effect on (+/-)-(E)-methyl1-2-[E-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR1), a NO donor .
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- HY-N0510A
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Aristolochic acid I sodium; TR 1736 sodium; Sodium aristolochate
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Biochemical Assay Reagents
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Others
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Aristolochic acid sodium salt (Sodium aristolate 1) is a component of some Chinese herbal medicines and is responsible for nephrotoxicity. It is a proagent that is activated by reduction of nitro groups to amines, resulting in the formation of cytotoxic DNA adducts.
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- HY-136458
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3-Amino-5-nitro-o-toluamide
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Parasite
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Infection
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3-ANOT is a metabolite of Dinitolmide (a nitroamide coccidiostat commonly used in poultry production) .
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- HY-W002727
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2-nitro-4-bromobenzoic acid
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Biochemical Assay Reagents
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Others
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4-Bromo-2-nitrobenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
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- HY-W001992
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3-nitro-2,6-dichloropyridine
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Biochemical Assay Reagents
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Others
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2,6-Dichloro-3-nitropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
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- HY-139031
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-
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- HY-N7041
-
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EBV
HSV
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Infection
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11-Oxomogroside IIa (11-oxomogroside II A1) is a cucurbitane glycoside extracted from the fruits of Siraitia grosVenorii.
11-Oxomogroside IIa has inhibitory effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), shows weak inhibitory effects on activation of (+/-)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor .
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- HY-127039
-
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Ser/Thr Protease
DNA/RNA Synthesis
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Metabolic Disease
Cancer
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Antipain is a protease inhibitor isolated from Actinomycetes. Antipain inhibits N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberrations. Antipain restricts uterine DNA synthesis and function in mice .
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- HY-127034
-
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Ser/Thr Protease
DNA/RNA Synthesis
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Metabolic Disease
Cancer
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Antipain dihydrochloride is a protease inhibitor isolated from Actinomycetes. Antipain dihydrochloride inhibits N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberrations. Antipain dihydrochloride restricts uterine DNA synthesis and function in mice .
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- HY-N11009
-
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EBV
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Infection
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11-Oxomogroside II A1 (compound 7) is an oxidized cucurbitin. It can be isolated from the ethanol extract of Rohanberry fruit. 11-Oxomogroside II A1 inhibits the activation of Epstein-Barr virus (EBV) early antigen (EBV-EA) induced by 12-O-tetradecanoylphorbol-13-acetate (TPA). 11-Oxomogroside II A1 also weakly inhibits the activation of (±)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor .
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- HY-32796
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2-Chloro-5-nitro-3-picoline
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Biochemical Assay Reagents
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Others
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2-Chloro-3-methyl-5-nitropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-32800
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6-Chloro-3-nitro-2-picoline
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Biochemical Assay Reagents
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Others
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6-Chloro-2-methyl-3-nitropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-W002231
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5-Bromo-3-nitro-2-pyridinamine
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Biochemical Assay Reagents
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Others
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2-Amino-5-bromo-3-nitropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-163292
-
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Bacterial
Parasite
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Infection
|
Antibacterial agent 180 (15g), an appropriate substrate for the type I nitro reductases (TcNTR I), is a promising antitrypanosomatid agent. Antibacterial agent 180 (15g) shows nonmutagenic potential against Salmonella typhimurium strains (TA98, TA100, and TA102) .
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- HY-105129A
-
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Others
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Cancer
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Pimonidazole is a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in tumor . Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after reduction of its nitro group, it can be used for qualitative and quantitative assessment of tumor hypoxia .
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- HY-105129
-
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Others
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Cancer
|
Pimonidazole is a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in tumor . Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after reduction of its nitro group, it can be used for qualitative and quantitative assessment of tumor hypoxia .
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- HY-148111
-
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Bacterial
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Infection
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Antitubercular agent-33 is a 2-aminothiazole derivative, shows potent antintubercular activity against Mycobacterium tuberculosis (Mtb) .
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- HY-101559S
-
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Isotope-Labeled Compounds
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Inflammation/Immunology
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10-Nitrooleate-d17 (nitrate) is the deuterium labeled 10-Nitrooleic acid nitrate. 10-Nitrooleic acid (CXA-10) nitrate, a nitro fatty acid, has potential effects in disease states in which oxidative stress, inflammation, fibrosis, and/or direct tissue toxicity play significant roles[1].
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- HY-136563
-
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Proteasome
Apoptosis
Reactive Oxygen Species
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Cancer
|
RA375 is a RPN13 (26S proteasome regulatory subunit) inhibitor. RA375 activates UPR signaling, ROS production and apoptosis. RA375 exhibits ten-fold greater activity against cancer lines than RA190, reflecting its nitro ring substituents and the addition of a chloroacetamide warhead .
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- HY-105129AS
-
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Isotope-Labeled Compounds
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Cancer
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Pimonidazole-d10 is the deuterium labeled Pimonidazole. Pimonidazole is a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in tumor[1]. Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after reduction of its nitro group, it can be used for qualitative and quantitative assessment of tumor hypoxia [2].
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- HY-101761
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TM5441
Maximum Cited Publications
6 Publications Verification
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PAI-1
Apoptosis
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Cancer
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TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), has IC50 values between 13.9 and 51.1 μM and induces intrinsic apoptosis in several human cancer cell lines. TM5441 attenuates Nω-nitro-l-arginine methyl ester-induced cardiac hypertension and vascular senescence .
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- HY-W325356
-
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Others
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Cancer
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Tert-butyl 3,5-dinitrobenzoate is an intermediate or reactant in organic synthesis and can also play a role in drug synthesis, dye preparation and other chemical fields.The nitro functional group of Tert-butyl 3,5-dinitrobenzoate has certain reactivity in organic chemistry and can participate in various reactions, such as electrophilic substitution, aromatic amine reaction, etc .
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- HY-149308
-
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Macrophage migration inhibitory factor (MIF)
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Infection
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MKA031 (compound 6y) is a non-competitive MIF inhibitor with an IC50 value of 1.7 μM. MKA031 (compound 6y) interferes with MIF/AIF interaction, MIF nuclear translocation, and N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced dependent cell death. MKA031 can be used in the study of chronic hepatitis C virus infection .
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- HY-101761A
-
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PAI-1
Apoptosis
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|
TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), has IC50 values between 13.9 and 51.1 μM. TM5441 induces intrinsic apoptosis in several human cancer cell lines. TM5441 attenuates Nω-nitro-l-arginine methyl ester-induced cardiac hypertension and vascular senescence .
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Cat. No. |
Product Name |
Type |
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- HY-15925
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NBT
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Chromogenic Substrates
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Nitro blue tetrazolium chloride (NBT) is a substrate for dehydrogenases; is used with the alkaline phosphatase substrate 5-Bromo-4-Chloro-3-Indolyl Phosphate (BCIP) in western blotting and immunohistological staining procedures .
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-
- HY-W273413
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NBD-H
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Fluorescent Dyes/Probes
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4-Hydrazino-7-nitro-benzofurazan hydrazine adduct is a fluorescent reagent for protein labeling.
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- HY-W179417
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Cat. No. |
Product Name |
Type |
-
- HY-W014626
-
|
Biochemical Assay Reagents
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4-Nitro-3-(trifluoromethyl)aniline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-W002060
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2-Amino-5-nitro-4-picoline
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Biochemical Assay Reagents
|
4-Methyl-5-nitropyridin-2-amine (2-Amino-5-nitro-4-picoline) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W016450
-
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Biochemical Assay Reagents
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2-Nitro-5-methylbenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-W001576
-
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Biochemical Assay Reagents
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6-Nitro-1H-indole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-157917
-
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Chelators
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Nitro-PAPS disodium dihydrate is a highly sensitive colometric reagent for Fe(II) detection with a maximal absorption wavelength of 592 nm. Nitro-PAPS disodium dihydrate is suitable for the determination of Fe(II) in serum and also be used to determine micro molar levels of Cu, Zn, Ni, Co and V .
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- HY-W002458
-
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Biochemical Assay Reagents
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4-Nitro-1H-pyrazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-136998
-
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Biochemical Assay Reagents
|
10-Nitrooleate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-N0510A
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Aristolochic acid I sodium; TR 1736 sodium; Sodium aristolochate
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Biochemical Assay Reagents
|
Aristolochic acid sodium salt (Sodium aristolate 1) is a component of some Chinese herbal medicines and is responsible for nephrotoxicity. It is a proagent that is activated by reduction of nitro groups to amines, resulting in the formation of cytotoxic DNA adducts.
|
-
- HY-W002727
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2-nitro-4-bromobenzoic acid
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Biochemical Assay Reagents
|
4-Bromo-2-nitrobenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W001992
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3-nitro-2,6-dichloropyridine
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Biochemical Assay Reagents
|
2,6-Dichloro-3-nitropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-32796
-
2-Chloro-5-nitro-3-picoline
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Biochemical Assay Reagents
|
2-Chloro-3-methyl-5-nitropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-32800
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6-Chloro-3-nitro-2-picoline
|
Biochemical Assay Reagents
|
6-Chloro-2-methyl-3-nitropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W002231
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5-Bromo-3-nitro-2-pyridinamine
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Biochemical Assay Reagents
|
2-Amino-5-bromo-3-nitropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P4561
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Cathepsin
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Others
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H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide that can serve as a substrate for cathepsin D, pepsin and pepsinogen. H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH has potential applications in biochemical analysis .
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- HY-P4556
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Biochemical Assay Reagents
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Others
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H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is a polypeptide that can be hydrolyzed by Rennin (HY-P2810). H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is commonly used as a biochemical reaction reagent .
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- HY-P4545
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Peptides
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Others
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Abz-Gly-p-nitro-Phe-Pro-OH is the fluorescent substrate angiotensin I converting enzyme (ACE-I) with 355 nm excitation and 405 nm emission wavelengths .
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- HY-P4725
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Peptides
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Others
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Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 is a fluorogenic substrate, that can be used for the fluorescence screening assay .
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- HY-W142003
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- HY-W002416
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- HY-W014049
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NO Synthase
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Others
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N'-Nitro-D-arginine, a nitric oxide synthesis inhibitor, also is a vasodilator that relaxes the smooth muscles and increases blood flow to the penis, improving erections. N'-Nitro-D-arginine also inhibits neutrophil migration by blocking receptors for tumour necrosis factor alpha (TNFα) and interleukin 8 (IL8) .
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- HY-75379
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- HY-P4546
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- HY-P4466
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HIV Protease
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Infection
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Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 is a fluorogenic substrate of HIV-1 protease. Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 can be used to test HIV-1 protease activity .
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
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- HY-113248S
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3-Nitro-L-tyrosine-d3 is the deuterium labeled 3-Nitro-L-tyrosine. 3-Nitro-L-tyrosine is a biomarker of nitrogen free radical species modified proteins in systemic autoimmunogenic conditions[1][2].
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- HY-113248S1
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3-Nitro-L-tyrosine- 13C6 is the 13C labeled 3-Nitro-L-tyrosine[1]. 3-Nitro-L-tyrosine is a biomarker of nitrogen free radical species modified proteins in systemic autoimmunogenic conditions[2].
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- HY-B1159S
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Nitroxoline-d4 is the deuterium labeled Nitroxoline. Nitroxoline is an antibiotic that has proven to be very effective at combating biofilm infections. Nitroxoline functions by chelating Fe2+ and Zn2+ ions from the biofilm matrix[1][2].
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- HY-W014340S
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2-Nitro-9H-fluorene-d9 is the deuterium labeled 2-Nitro-9H-fluorene[1].
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- HY-101559S
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10-Nitrooleate-d17 (nitrate) is the deuterium labeled 10-Nitrooleic acid nitrate. 10-Nitrooleic acid (CXA-10) nitrate, a nitro fatty acid, has potential effects in disease states in which oxidative stress, inflammation, fibrosis, and/or direct tissue toxicity play significant roles[1].
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- HY-105129AS
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Pimonidazole-d10 is the deuterium labeled Pimonidazole. Pimonidazole is a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in tumor[1]. Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after reduction of its nitro group, it can be used for qualitative and quantitative assessment of tumor hypoxia [2].
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Cat. No. |
Product Name |
Application |
Reactivity |
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- HY-P81216
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NO tyrosine; nTyr; nitrotyrosine; nitro-Tyrosine; nitro Tyrosine.
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WB; ELISA; IHC-P; IHC-F; Flow-Cyt; IF
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Human, Rat(predicted: Mouse) |
3-Nitrotyrosine Antibody is an unconjugated, rabbit-derived, anti-3-Nitrotyrosine polyclonal antibody. 3-Nitrotyrosine Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, rat, and predicted: mouse background without labeling.
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Cat. No. |
Product Name |
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Classification |
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- HY-154146
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Azide
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5-Nitro-1-(3-azido-3-deoxy-β-D-ribofuranosyl)-2(1H)-pyridinone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 5-Nitro-1-(3-azido-3-deoxy-β-D-ribofuranosyl)-2(1H)-pyridinone is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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