Antitubercular agent-33
Based on 1 Customer Validation
Antitubercular agent-33 is a 2-aminothiazole derivative, shows potent antintubercular activity against Mycobacterium tuberculosis (Mtb).
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 476317-29-0
- Formula: C15H10N4O3S
- Molecular Weight:326.33
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Anti-Infection Compound Library
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Antibacterial Compound Library
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Heterocyclic Compound Library
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Biological Activity
Antitubercular agent-33 (compound 49) exerts antitubercular effects with MIC values of 1.6-3.1 μM (in 7H9-glucose media) and 0.78 μM (in GAST media), respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 476317-29-0
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Appearance Solid
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Molecular Weight 326.33
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Formula C15H10N4O3S
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Color White to off-white
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SMILES
O=C(NC1=NC(C2=NC=CC=C2)=CS1)C3=CC=CC=C3[N+]([O-])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (306.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0644 mL | 15.3219 mL | 30.6438 mL | 76.6096 mL |
| 5 mM | 0.6129 mL | 3.0644 mL | 6.1288 mL | 15.3219 mL | |
| 10 mM | 0.3064 mL | 1.5322 mL | 3.0644 mL | 7.6610 mL | |
| 15 mM | 0.2043 mL | 1.0215 mL | 2.0429 mL | 5.1073 mL | |
| 20 mM | 0.1532 mL | 0.7661 mL | 1.5322 mL | 3.8305 mL | |
| 25 mM | 0.1226 mL | 0.6129 mL | 1.2258 mL | 3.0644 mL | |
| 30 mM | 0.1021 mL | 0.5107 mL | 1.0215 mL | 2.5537 mL | |
| 40 mM | 0.0766 mL | 0.3830 mL | 0.7661 mL | 1.9152 mL | |
| 50 mM | 0.0613 mL | 0.3064 mL | 0.6129 mL | 1.5322 mL | |
| 60 mM | 0.0511 mL | 0.2554 mL | 0.5107 mL | 1.2768 mL | |
| 80 mM | 0.0383 mL | 0.1915 mL | 0.3830 mL | 0.9576 mL | |
| 100 mM | 0.0306 mL | 0.1532 mL | 0.3064 mL | 0.7661 mL |
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