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GRK2 Inhibitor 1 (methyl 5-[2-(5-nitro-2-furyl)vinyl]-2-furoate) is a GRK2 (β-ARK1) inhibitor.

For research use only. We do not sell to patients.

GRK2 Inhibitor 1 Chemical Structure

GRK2 Inhibitor 1 Chemical Structure

CAS No. : 24269-96-3

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 165 In-stock
Solution
10 mM * 1 mL in DMSO USD 165 In-stock
Solid
5 mg USD 150 In-stock
10 mg USD 250 In-stock
25 mg USD 550 In-stock
50 mg USD 850 In-stock
100 mg USD 1350 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

GRK2 Inhibitor 1 (methyl 5-[2-(5-nitro-2-furyl)vinyl]-2-furoate) is a GRK2 (β-ARK1) inhibitor[1].

Molecular Weight

263.20

Formula

C12H9NO6
CAS No.
Appearance

Solid

Color

Yellow to brown

SMILES

O=C(OC)C1=CC=C(O1)/C=C/C2=CC=C(O2)[N+]([O-])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 41.67 mg/mL (158.32 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7994 mL 18.9970 mL 37.9939 mL
5 mM 0.7599 mL 3.7994 mL 7.5988 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.7994 mL 18.9970 mL 37.9939 mL 94.9848 mL
5 mM 0.7599 mL 3.7994 mL 7.5988 mL 18.9970 mL
10 mM 0.3799 mL 1.8997 mL 3.7994 mL 9.4985 mL
15 mM 0.2533 mL 1.2665 mL 2.5329 mL 6.3323 mL
20 mM 0.1900 mL 0.9498 mL 1.8997 mL 4.7492 mL
25 mM 0.1520 mL 0.7599 mL 1.5198 mL 3.7994 mL
30 mM 0.1266 mL 0.6332 mL 1.2665 mL 3.1662 mL
40 mM 0.0950 mL 0.4749 mL 0.9498 mL 2.3746 mL
50 mM 0.0760 mL 0.3799 mL 0.7599 mL 1.8997 mL
60 mM 0.0633 mL 0.3166 mL 0.6332 mL 1.5831 mL
80 mM 0.0475 mL 0.2375 mL 0.4749 mL 1.1873 mL
100 mM 0.0380 mL 0.1900 mL 0.3799 mL 0.9498 mL
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GRK2 Inhibitor 1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GRK2 Inhibitor 124269-96-3OthersG protein-coupled receptor kinaseInhibitorinhibitorinhibit

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