GRK2 Inhibitor 1
Based on 1 Customer Validation
GRK2 Inhibitor 1 (methyl 5-[2-(5-nitro-2-furyl)vinyl]-2-furoate) is a dual GRK2/β-ARK1 inhibitor that induces dopamine (DA) inhibition reversal (DIR). GRK2 Inhibitor 1 can also block serotonin-induced or neurotensin-induced DIR reversal. Note: DIR refers to the phenomenon in which neurons in addiction-related brain pathways become less sensitive to DA inhibition when exposed to moderate concentrations of DA for a long time.
For research use only. We do not sell to patients.
- Purity: 98.06%
- CAS No.: 24269-96-3
- Formula: C12H9NO6
- Molecular Weight:263.20
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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GRK2 |
Chemical Information
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CAS No. 24269-96-3
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Appearance Solid
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Molecular Weight 263.20
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Formula C12H9NO6
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Color Yellow to brown
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SMILES
O=C(OC)C1=CC=C(O1)/C=C/C2=CC=C(O2)[N+]([O-])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 41.67 mg/mL (158.32 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7994 mL | 18.9970 mL | 37.9939 mL | 94.9848 mL |
| 5 mM | 0.7599 mL | 3.7994 mL | 7.5988 mL | 18.9970 mL | |
| 10 mM | 0.3799 mL | 1.8997 mL | 3.7994 mL | 9.4985 mL | |
| 15 mM | 0.2533 mL | 1.2665 mL | 2.5329 mL | 6.3323 mL | |
| 20 mM | 0.1900 mL | 0.9498 mL | 1.8997 mL | 4.7492 mL | |
| 25 mM | 0.1520 mL | 0.7599 mL | 1.5198 mL | 3.7994 mL | |
| 30 mM | 0.1266 mL | 0.6332 mL | 1.2665 mL | 3.1662 mL | |
| 40 mM | 0.0950 mL | 0.4749 mL | 0.9498 mL | 2.3746 mL | |
| 50 mM | 0.0760 mL | 0.3799 mL | 0.7599 mL | 1.8997 mL | |
| 60 mM | 0.0633 mL | 0.3166 mL | 0.6332 mL | 1.5831 mL | |
| 80 mM | 0.0475 mL | 0.2375 mL | 0.4749 mL | 1.1873 mL | |
| 100 mM | 0.0380 mL | 0.1900 mL | 0.3799 mL | 0.9498 mL |
GRK2 Inhibitor 1 Related Classifications
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