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oxygen and hydrogen peroxide

" in MedChemExpress (MCE) Product Catalog:

34

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9

Fluorescent Dyes

1

Biochemical Assay Reagents

2

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P2902
    Glucose oxidase
    5+ Cited Publications

    		 Endogenous Metabolite Cancer
    Glucose oxidase is used in the food and beverage industry as a preservative and stabilizer and is commonly derived from the fungus Aspergillus niger. Glucose oxidase can react with intracellular glucose and oxygen (O2) to produce hydrogen peroxide (H2O2) and gluconic acid, which can cut off the nutrition source of cancer cells and consequently inhibit their proliferation .
    Glucose oxidase
  • HY-W011664
    1,3-Diphenylisobenzofuran
    Maximum Cited Publications
    28 Publications Verification

    DPBF

    		 Fluorescent Dye Reactive Oxygen Species (ROS) Others
    1,3-Diphenylisobenzofuran (DPBF) has been developed as a selective probe for the detection and quantitative determination of hydrogen peroxide in samples containing different reactive nitrogen and oxygen species (RNOS). DPBF is a fluorescent probe which, for almost 20 years, was believed to react in a highly specific manner toward some reactive oxygen species such as singlet oxygen and hydroxy, alkyloxy or alkylperoxy radicals .
    1,3-Diphenylisobenzofuran
  • HY-15930
    TMB
    5+ Cited Publications

    BM blue; Sure Blue TMB

    		 Fluorescent Dye MOFs Reactive Oxygen Species (ROS) Others
    TMB is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922 .
    TMB
  • HY-129064
    Superoxide dismutase, Porcine erythrocytes
    2 Publications Verification

    SOD

    		 SOD Inflammation/Immunology Cancer
    Superoxide dismutase, Porcine erythrocytes (SOD) is the only antioxidant enzyme that scavenges the superoxide anion by converting this free radical to oxygen and hydrogen peroxide, thus preventing peroxynitrite production and further damage. Superoxide dismutase, Porcine erythrocytes is extensively researched and used in anti-inflammatory, antitumor, radiation protection, and antisenility applications .
    Superoxide dismutase, Porcine erythrocytes
  • HY-15930A
    TMB dihydrochloride
    5+ Cited Publications

    BM blue dihydrochloride; Sure Blue TMB dihydrochloride

    		 Fluorescent Dye Reactive Oxygen Species (ROS) Others
    TMB dihydrochloride is the dihydrochloride form of TMB (HY-15930). TMB dihydrochloride is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB dihydrochloride can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB dihydrochloride can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922 .
    TMB dihydrochloride
  • HY-129115
    S1QEL1.1

    		Reactive Oxygen Species (ROS) Caspase Others
    S1QEL1.1 is a small molecule inhibitor that specifically inhibits the generation of superoxide and hydrogen peroxide at the IQ site during reverse electron transfer in mitochondrial respiratory chain complex I (Complex I), with an IC50 of 0.07 μM. S1QEL1.1 can significantly reduce the activation of cysteine-aspartic protease (caspase) triggered by endoplasmic reticulum stress. S1QEL1.1 helps to decrease excessive proliferation of stem cells by inhibiting the Reactive Oxygen Species signaling pathway initiated by endoplasmic reticulum stress .
    S1QEL1.1
  • HY-E70385
    Oxalate Oxidase

    		Endogenous Metabolite Others
    Oxalate Oxidase, or oxalate oxidase, catalyzes the oxidation of oxalic acid to hydrogen peroxide and carbon dioxide in the presence of oxygen. Oxalate Oxidase can be found in a variety of plants (such as barley) and microorganisms and can be used to treat wastewater and filtrates containing oxalic acid .
    Oxalate Oxidase
  • HY-15930B
    TMB dihydrochloride x.hydrate
    5+ Cited Publications

    Sure Blue TMB dihydrochloride x.hydrate

    		 Fluorescent Dye Reactive Oxygen Species (ROS) Others
    TMB (dihydrochloride x.hydrate) is the dihydrochloride x hydrate form of TMB (HY-15930). TMB (dihydrochloride x.hydrate) is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB (dihydrochloride x.hydrate) can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB (dihydrochloride x.hydrate) can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922 .
    TMB dihydrochloride x.hydrate
  • HY-105005
    Crisdesalazine

    AAD-2004

    		 Prostaglandin Receptor PGE synthase Reactive Oxygen Species (ROS) Apoptosis Neurological Disease Inflammation/Immunology
    Crisdesalazine (AAD-2004) is a microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor. Crisdesalazine acts as a potent free radical scavenger that directly neutralizes reactive oxygen species (ROS) including hydrogen peroxide, exerting neuroprotective effects against apoptosis and axonal damage. Crisdesalazine inhibits PGE2 production, mediates inflammatory responses, and promotes the conversion of macrophages from the pro-inflammatory M1 phenotype to the anti-inflammatory M2 phenotype. Crisdesalazine is applicable to neuroprotection research in multiple sclerosis and spinal cord injury .
    Crisdesalazine
  • HY-135849C
    Catalase, trichoderma reesei

    		Reactive Oxygen Species (ROS) Inflammation/Immunology Cancer
    Catalase, trichoderma reesei is a catalase derived from Trichoderma reesei. Catalase, trichoderma reesei dismutates hydrogen peroxide into oxygen and water, helping cells resist oxidative damage caused by hydrogen peroxide .
    Catalase, trichoderma reesei
  • HY-W037819
    6-Methylpterin

    		Drug Derivative Metabolic Disease
    6-Methylpterin is a derivative of the essential B vitamin Folic acid (HY-16637). 6-Methylpterin generates singlet oxygen and hydrogen peroxide when exposed to Photoirradiation. 6-Methylpterin can be used for the detection of pterins in urine .
    6-Methylpterin
  • HY-15930C
    TMB monosulfate
    5+ Cited Publications

    BM blue monosulfate; Sure Blue TMB monosulfate

    		 Fluorescent Dye Reactive Oxygen Species (ROS) Others
    TMB monosulfate is the monosulfate form of TMB (HY-15930). TMB monosulfate is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB monosulfate can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB monosulfate can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922 .
    TMB monosulfate
  • HY-N3027
    Soyasaponin Aa
    1 Publications Verification

    		 PPAR Reactive Oxygen Species (ROS) Metabolic Disease
    Soyasaponin Aa is a soyasaponin that can be found in soy. Soyasaponin Aa suppresses PPARγ transcriptional activity, reduces PPARγ and C/EBPα expression, inhibits adipocyte differentiation and lipid accumulation, and reduces adipogenic marker gene expression. Soyasaponin Aa reduces hydrogen peroxide-induced reactive oxygen species (ROS) production and malondialdehyde levels. Soyasaponin Aa exhibits cellular antioxidant activity. Soyasaponin Aa can be used for the research of obesity .
    Soyasaponin Aa
  • HY-W927359
    Fluorescein hydrazide (3,6-Dihydroxyxanthane)

    		Fluorescent Dye Others
    Fluorescein hydrazide (3,6-Dihydroxyxanthane) is a fluorescein dye that can be used for the fluorophotometric determination of hydrogen peroxide (H2O2) and other reactive oxygen species (ROS) .
    Fluorescein hydrazide (3,6-Dihydroxyxanthane)
  • HY-DY1053
    1,3-Diphenylisobenzofuran (solution)

    		Fluorescent Dye Reactive Oxygen Species (ROS) Others
    1,3-Diphenylisobenzofuran (DPBF) (solution) has been developed as a selective probe for the detection and quantitative determination of hydrogen peroxide in samples containing different reactive nitrogen and oxygen species (RNOS). DPBF is a fluorescent probe which, for almost 20 years, was believed to react in a highly specific manner toward some reactive oxygen species such as singlet oxygen and hydroxy, alkyloxy or alkylperoxy radicals .
    Solvent and concentration: DMSO: 10 mM
    The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
    1,3-Diphenylisobenzofuran (solution)
  • HY-15930R
    TMB (Standard)

    BM blue (Standard); Sure Blue TMB (Standard)

    		 Fluorescent Dye Reactive Oxygen Species (ROS) Reference Standards Others
    TMB (Standard) is the analytical standard of TMB. This product is intended for research and analytical applications. TMB is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922 .
    TMB (Standard)
  • HY-P2888A
    Bilirubin oxidase, bacillus cereus

    BOD, bacillus cereus

    		 Endogenous Metabolite Metabolic Disease
    Bilirubin oxidase, bacillus cereus is a multi-copper oxidase that catalyzes the oxidation of bilirubin into biliverdin, as well as other tetrapyrroles, phenols, and aryl diamines. Bilirubin oxidase, bacillus cereus can serve as a single-enzyme deoxygenator, catalyzing the direct reduction of oxygen to water in the presence of electron donor substrates, without releasing hydrogen peroxide. Bilirubin oxidase, bacillus cereus can be used to develop enzyme-based biosensors .
    Bilirubin oxidase, bacillus cereus
  • HY-P2888C
    Bilirubin oxidase, Bacillus pumilus

    BOD, Bacillus pumilus

    		 Endogenous Metabolite Metabolic Disease
    Bilirubin oxidase (BOD), Bacillus pumilus is a multicopper oxidase that catalyzes the oxidation of bilirubin to biliverdin, as well as other tetrapyrrole, phenols, and aryl diamines. Bilirubin oxidase, Bacillus pumilus can serve as a single-enzyme deoxygenator, catalyzing the direct reduction of oxygen to water in the presence of electron donor substrates, without releasing hydrogen peroxide. Bilirubin oxidase, Bacillus pumilus can be used to develop enzyme-based biosensors .
    Bilirubin oxidase, Bacillus pumilus
  • HY-136855
    MitoPBN

    		Sirtuin AMPK PGC-1α Apoptosis Reactive Oxygen Species (ROS) Metabolic Disease
    MitoPBN is a AMPK/SIRT3/PGC-1α axis modulator, reactive oxygen species scavenger and mitochondrial function enhancer. MitoPBN increases the phosphorylation level of AMPK, restores SIRT3 expression and reverses the down-regulation of PGC-1α, thereby promoting mitochondrial biogenesis. MitoPBN regulates glucose metabolism, reduces blood glucose by inhibiting hepatic gluconeogenesis and increasing hepatic glucose uptake, while scavenging mitochondrial superoxide anion/hydrogen peroxide, maintaining membrane potential and increasing ATP production. MitoPBN also reduces cell apoptosis, improves sperm motility, survival rate and membrane integrity, but may induce reductive stress in cryopreserved sperm at high concentrations. MitoPBN is widely applicable to research related to diabetes and type 2 diabetes .
    MitoPBN
  • HY-N3027R
    Soyasaponin Aa (Standard)

    		Reference Standards PPAR Reactive Oxygen Species (ROS) Metabolic Disease
    Soyasaponin Aa (Standard) is the analytical standard of Soyasaponin Aa (HY-N3027). Soyasaponin Aa is a soyasaponin that can be found in soy. Soyasaponin Aa suppresses PPARγ transcriptional activity, reduces PPARγ and C/EBPα expression, inhibits adipocyte differentiation and lipid accumulation, and reduces adipogenic marker gene expression. Soyasaponin Aa reduces hydrogen peroxide-induced reactive oxygen species (ROS) production and malondialdehyde levels. Soyasaponin Aa exhibits cellular antioxidant activity. Soyasaponin Aa can be used for the research of obesity .
    Soyasaponin Aa (Standard)
  • HY-169831
    HUP-55

    		α-synuclein Neurological Disease
    HUP-55 is a prolyl endopeptidase inhibitor (IC50 = 5 nM). HUP-55 reduces the dimerization of α-synuclein in Neuro2a cells and induces autophagy (Autophagy) in HEK293 cells. It also decreases the increase in reactive oxygen species (ROS) production induced by hydrogen peroxide in SH-SY5Y cells at a concentration of 10 μM. In a mouse Parkinson’s disease model, HUP-55 (10 mg/kg) improves motor function (reduces the use frequency of the impaired paw) and decreases the levels of harmful oligomers of α-synuclein in the striatum caused by overexpression of α-synuclein .
    HUP-55
  • HY-D3168
    PCL-2

    		Fluorescent Dye Reactive Oxygen Species (ROS) Inflammation/Immunology
    PCL-2 is a reactive oxygen species-responsive fluorescent probe that shows almost no response to biologically relevant reactive oxygen species other than hydrogen peroxide. PCL-2 reacts with hydrogen peroxide to release 6-hydroxy-2-cyanobenzothiazole. PCL-2 can be used for chemoselective imaging of hydrogen peroxide in in vitro models and acute inflammation mouse models. PCL-2 is applicable to studies related to acute inflammation .
    PCL-2
  • HY-135849H
    Catalase, Murine

    		Biochemical Assay Reagents Metabolic Disease
    Catalase, Murine (EC 1.11.1.6) activates the decomposition of hydrogen peroxide, a reactive oxygen species, into water and oxygen. Catalase functions as a natural antioxidant, protecting cells against oxidative damage to proteins, lipids and nucleic acids.
    Catalase, Murine
  • HY-135849D
    Catalase, Corynebacterium glutamicum

    		Biochemical Assay Reagents Metabolic Disease
    Catalase, Corynebacterium glutamicum (EC 1.11.1.6) activates the decomposition of hydrogen peroxide, a reactive oxygen species, into water and oxygen. Catalase functions as a natural antioxidant, protecting cells against oxidative damage to proteins, lipids and nucleic acids.
    Catalase, Corynebacterium glutamicum
  • HY-135849E
    Catalase, Corynebacterium sp.

    		Biochemical Assay Reagents Metabolic Disease
    Catalase, Corynebacterium sp. (EC 1.11.1.6) activates the decomposition of hydrogen peroxide, a reactive oxygen species, into water and oxygen. Catalase functions as a natural antioxidant, protecting cells against oxidative damage to proteins, lipids and nucleic acids.
    Catalase, Corynebacterium sp.
  • HY-P2848E
    Cholesterol oxidase, PEG Modified

    		Biochemical Assay Reagents Others
    Cholesterol oxidase, PEG Modified, is a polyethylene glycol (PEG) modified cholesterol oxidase. Cholesterol oxidase is an enzyme that catalyzes the oxidation of cholesterol to cholesterol-4-en-3-one and hydrogen peroxide in the presence of oxygen.
    Cholesterol oxidase, PEG Modified
  • HY-129064D
    Superoxide Dismutase, Roxburgh

    		SOD Metabolic Disease
    Superoxide Dismutase, Roxburgh (EC 1.15.1.1) catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. Superoxide Dismutase plays a critical role in the defense of cells against the toxic effects of oxygen radicals. Superoxide Dismutase competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby Superoxide Dismutase promotes the activity of NO.
    Superoxide Dismutase, Roxburgh
  • HY-129064C
    Superoxide Dismutase, Bovine

    		SOD Metabolic Disease
    Superoxide Dismutase, Bovine (EC 1.15.1.1) catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. Superoxide Dismutase plays a critical role in the defense of cells against the toxic effects of oxygen radicals. Superoxide Dismutase competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby Superoxide Dismutase promotes the activity of NO.
    Superoxide Dismutase, Bovine
  • HY-129064H
    Superoxide Dismutase, Horseradish

    		Endogenous Metabolite Metabolic Disease
    Superoxide dismutase, Horseradish (EC 1.15.1.1), catalyzes the dismutation of superoxide radicals into hydrogen peroxide and molecular oxygen. Superoxide dismutase (SOD) plays a crucial role in cellular defense against the toxic effects of oxygen free radicals. Superoxide dismutase competes with nitric oxide (NO) for superoxide anions (which react with NO to form peroxynitrite), thereby promoting NO activity.
    Superoxide Dismutase, Horseradish
  • HY-E70944
    Soy Superoxide Dismutase

    		SOD Metabolic Disease
    Soy Superoxide Dismutase (EC 1.15.1.1) catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. Superoxide Dismutase plays a critical role in the defense of cells against the toxic effects of oxygen radicals. Superoxide Dismutase competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby Superoxide Dismutase promotes the activity of NO.
    Soy Superoxide Dismutase
  • HY-129064E
    Superoxide Dismutase, Escherichia coli

    		Endogenous Metabolite Metabolic Disease
    Superoxide Dismutase, Escherichia coli (EC 1.15.1.1), catalyzes the dismutation of superoxide radicals into hydrogen peroxide and molecular oxygen. Superoxide dismutase (SOD) plays a crucial role in cellular defense against the toxic effects of oxygen free radicals. Superoxide dismutase competes with nitric oxide (NO) for superoxide anions (which react with NO to form peroxynitrite), thereby promoting NO activity.
    Superoxide Dismutase, Escherichia coli
  • HY-182333
    AChE-IN-112

    		Cholinesterase (ChE) Neurological Disease
    AChE-IN-112 is an acetylcholinesterase (AChE) inhibitor with an IC50 of 0.41 μM. AChE-IN-112 scavenges various reactive oxygen and reactive nitrogen species, including DPPH, ABTS, NO, hydroxyl and hydrogen peroxide free radicals. AChE-IN-112 can be used for the research of Alzheimer's disease .
    AChE-IN-112
  • HY-D3139
    Pinkment-OAc

    		Fluorescent Dye Others
    Pinkment-OAc is an AND logic gate-based dual-analyte-dependent fluorescence inducer (Ex/Em = 545 nm/590 nm) that can be used for the simultaneous detection of hydrogen peroxide (H2O2) and esterases (e.g., porcine liver esterase PLE). Pinkment-OAc triggers a fluorescent response only when both esterase and hydrogen peroxide are present .
    Pinkment-OAc
  • HY-180828
    iNOs-IN-8

    		NO Synthase Cardiovascular Disease Neurological Disease
    iNOs-IN-8 (Compound 13h) is an efficient and highly selective inducible nitric oxide synthase (iNOS) inhibitor, with an IC50 of 238 nM. iNOs-IN-8 exhibits significant neuroprotective effects in oxygen-glucose deprivation/reoxygenation (OGD/R) and hydrogen peroxide-induced neuronal and endothelial cell damage. iNOs-IN-8 significantly reduces the volume of cerebral infarction and improves neurological function in rat models. iNOs-IN-8 can be used for the study of ischemic stroke .
    iNOs-IN-8

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