Catalase, trichoderma reesei
Based on 6 publication(s) in Google Scholar
Catalase, trichoderma reesei is a catalase derived from Trichoderma reesei. Catalase, trichoderma reesei dismutates hydrogen peroxide into oxygen and water, helping cells resist oxidative damage caused by hydrogen peroxide.
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- CAS No.: 9001-05-2
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Catalase, trichoderma reesei
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Cell Imaging/Staining
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Cell Proliferation/Viability Assay
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WB
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WB
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In Vivo Efficacy Study
Activité biologique
Description
In Vitro
Catalase is primarily localized in peroxisomes and can dynamically shuttle between the cytoplasm and peroxisomes to protect cells from oxidative damage. Abnormalities in its expression and activity are closely associated with tumorigenesis and tumor progression[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 9001-05-2
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SMILES
[Catalase, trichoderma reesei]
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (6)
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Journal Impact Factor
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Most Recent
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Nat Chem Biol
2025 Jun 2. PMID: 40456963 -
Cancer Lett
Vesicular QSOX1-MMP2 from inflammatory cancer-associated fibroblasts degrades the extracellular matrix to drive colorectal cancer pulmonary dissemination. [Abstract]2026 Sep 28:656:218645. PMID: 42217558 -
Catalase, trichoderma reesei purchased from MedChemExpress. Usage Cited in: BioChip J. 2025 Aug 1.
ROS scavenger Catalase, Aspergillus niger (5 μg/mL; 5 d) downregulated CDK5 expression and upregulated PP2A expression on the AD neuroglial model.
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Eur J Pharmacol
Dihydrotanshinone I potentiates the anti-tumor activity of cisplatin by activating ROS-mediated ER stress through targeting HSPD1 in lung cancer cells. [Abstract]2025 May 5:994:177378. PMID: 39952584
Catalase, trichoderma reesei purchased from MedChemExpress. Usage Cited in: Eur J Pharmacol. 2025 May 5:994:177378. [Abstract]
Catalase, Aspergillus niger (1000 unit/mL; 1.5 h) effectively attenuated the reduction in viability of H460 and H520 cells.
Catalase, trichoderma reesei purchased from MedChemExpress. Usage Cited in: Eur J Pharmacol. 2025 May 5:994:177378. [Abstract]
Catalase, Aspergillus niger (1000 unit/mL; 1.5 h) effectively increased ATF4, CHOP and p-JNK expressions in H460 and H520 cells.
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Int Immunopharmacol
Apolipoprotein C3 (ApoC3) facilitates NLRP3 mediated pyroptosis of macrophages through mitochondrial damage by accelerating of the interaction between SCIMP and SYK pathway in acute lung injury. [Abstract]2024 Feb 15:128:111537. PMID: 38232538
Catalase, trichoderma reesei purchased from MedChemExpress. Usage Cited in: Int Immunopharmacol. 2024 Feb 15:128:111537. [Abstract]
ROS inhibitor Catalase, Aspergillus niger (500 U/L; 2 h) suppressed NLRP3/Caspase-1/GSDMD protein expressions in BMDM by LPS + ATP + ApoC3.
Catalase, trichoderma reesei purchased from MedChemExpress. Usage Cited in: Int Immunopharmacol. 2024 Feb 15:128:111537. [Abstract]
Catalase, Aspergillus niger (30 mg/kg; i.p.) reduced pulmonary injury and inhibited the lung injury score and W/D ratio of acute lung injury (ALI) mice.
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Protocole
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ROS/oxidative-stress fluorescent staining
ROS/oxidative-stress fluorescent staining uses cell-permeant fluorogenic probes that become fluorescent after oxidation inside cells or tissues; commonly used examples include DCFH-DA/DCFDA for broad cellular oxidant detection, DHE for superoxide-related signal detection, MitoSOX for mitochondrial superoxide-related signal detection, and CellROX probes for oxidative-stress-associated fluorescence readouts. The assay detects probe oxidation rather than a single ROS species unless the probe and analysis method have been chemically validated for that species. DCFH-DA enters cells, is deacetylated by intracellular esterases to DCFH, and produces fluorescent DCF after oxidation, so the readout is used as an operational measure of total cellular oxidative stress rather than a species-specific ROS measurement. DHE and MitoSOX can report superoxide-related oxidation, but red fluorescence alone can include non-specific ethidium-like oxidation products; HPLC or optimized spectral approaches are
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)