AChE-IN-112
AChE-IN-112 is an acetylcholinesterase (AChE) inhibitor with an IC50 of 0.41 μM. AChE-IN-112 scavenges various reactive oxygen and reactive nitrogen species, including DPPH, ABTS, NO, hydroxyl and hydrogen peroxide free radicals. AChE-IN-112 can be used for the research of Alzheimer's disease.
For research use only. We do not sell to patients.
- Formula: C27H28N4O7S
- Molecular Weight:552.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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AChE 0.41 μM (IC50) |
AChE-IN-112 (Compound 4r) (62.5 µg/mL) shows weak inhibition of BChE, with 32.51% inhibition at a concentration of 62.5 µg/mL[1].
AChE-IN-112 (10 μg/mL) possesses notable in vitro antioxidant activity, with a total antioxidant capacity of 66.80 mg gallic acid/g, an IRP level of 96.7 µM, and potent radical scavenging activity against DPPH, ABTS, NO, OH, and H2O2 radicals[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 552.60
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Formula C27H28N4O7S
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SMILES
CCCS(=O)(OC1=CC(/C=N/NC(COC2=CC=C(C3=NC4=CC=CC=C4N3)C=C2OC)=O)=CC=C1OC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AChE-IN-112 Related Classifications
HY-182333 Related Classifications
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