2. Others NF-κB Metabolic Enzyme/Protease Immunology/Inflammation
  3. Fluorescent Dye Reactive Oxygen Species (ROS)
  4. TMB dihydrochloride x.hydrate

TMB dihydrochloride x.hydrate  (Synonyms: Sure Blue TMB dihydrochloride x.hydrate)

Cat. No.: HY-15930B Purity: 99.89%
COA
SDS
Handling Instructions Technical Support

TMB (dihydrochloride x.hydrate) is the dihydrochloride x hydrate form of TMB (HY-15930). TMB (dihydrochloride x.hydrate) is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB (dihydrochloride x.hydrate) can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB (dihydrochloride x.hydrate) can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922.

For research use only. We do not sell to patients.

CAS No. : 207738-08-7

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Customer Review

Based on 6 publication(s) in Google Scholar

Other Forms of TMB dihydrochloride x.hydrate:

TMB dihydrochloride x.hydrate Related Antibodies

Top Publications Citing Use of Products

    TMB dihydrochloride x.hydrate purchased from MedChemExpress. Usage Cited in: Nano Res. 2026 Feb 6.

    Ov-ZBC showed strong characteristic peaks, indicating its higher photocatalytic ROS generation capability. The results of TMB and MB chromogenic reactions shown in Fig.

    TMB dihydrochloride x.hydrate purchased from MedChemExpress. Usage Cited in: Chem Eng J. 2025 Nov 24;526:171230.

    A diagram showing the chemical reaction formula of TMB assay, MB assay, and DTNB assay.

    TMB dihydrochloride x.hydrate purchased from MedChemExpress. Usage Cited in: Chem Eng J. 2025 Nov 24;526:171230.

    The results of TMB assay.

    • Biological Activity

    • Purity & Documentation

    • References

    • Customer Review

    Description

    TMB (dihydrochloride x.hydrate) is the dihydrochloride x hydrate form of TMB (HY-15930). TMB (dihydrochloride x.hydrate) is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB (dihydrochloride x.hydrate) can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB (dihydrochloride x.hydrate) can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922[1][2].
    In Vitro

    TMB (dihydrochloride x.hydrate) can tightly bind to Escherichia coli ATCC 25922 cells instead of being internalized to detect singlet oxygen produced by the outer membrane[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    TMB dihydrochloride x.hydrate Related Antibodies
    Formula

    C16H22Cl2N2.xH2O
    CAS No.
    Appearance

    Solid

    Color

    Off-white to light brown

    SMILES

    NC1=C(C)C=C(C2=CC(C)=C(N)C(C)=C2)C=C1C.[x].Cl.Cl.O
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Store at room temperature, keep dry and cool

    In solvent -80°C 1 year
    -20°C 6 months
    Solvent & Solubility
    In Vitro: 

    DMSO : 10 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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    This equation is commonly abbreviated as: C1V1 = C2V2

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    Working solution concentration: mg/mL
    Purity & Documentation

    Purity: 99.89%

    SDS (396 KB)

    COA (250 KB) HNMR (258 KB) LCMS (102 KB)

    Handling Instructions (2659 KB)
    References
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    TMB dihydrochloride x.hydrate Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    TMB dihydrochloride x.hydrate207738-08-7Sure Blue TMB dihydrochloride x.hydrateFluorescent DyeReactive Oxygen Species (ROS)dyestuffchromogenic agentsinglet oxygenprobeInhibitorinhibitorinhibit

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