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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
35 Results for "
schistosomiasis
" in MedChemExpress (MCE) Product Catalog:
Products (35)
35 Results for "schistosomiasis" in MCE Product Catalog:
3
Category:
Infection Microorganisms Ginkgoaceae Terpenoids Ginkgo biloba L. Diterpenoids Plants Disease Research Fields Food Research
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2
2 Cited Publications
Cat. No.: HY-B0244
CAS No.: 55268-74-1
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Praziquantel is a broadly effective trematocide and cestocide, the initial effect of praziquantel on the schistosome may be an interaction of the drug with lipid constituents of the tegumental membrane. Praziquantel is used for the research of schistosomiasis .
1
1 Cited Publications
Cat. No.: HY-10416
CAS No.: 21738-42-1
Oxamniquine is a potent agent for the treatment of schistosomiasis.
Cat. No.: HY-N10534
CAS No.: 71208-06-5
Synonyms: Lewis X
Category:
Infection Polysaccharides Animals Disease Research Fields Inflammation/Immunology Saccharides Cancer
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Cat. No.: HY-N4184
CAS No.: 91433-17-9
Cat. No.: HY-Y1890C
CAS No.: 61791-12-6
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(R)-Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R)-Praziquantel acts as an antischistosomal eutomer .
Cat. No.: HY-175184
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LSD1-IN-44 (Compound 19) is a LSD1 inhibitor with an IC50 of 0.02 μM for LSD1-CoREST enzymatic complex. LSD1-IN-44 has significant antischistosomal activity against transformed schistosomula (NTS) and Schistosoma mansoni adult worms while showing a delayed onset of action towards juvenile forms. LSD1-IN-44 has no significant toxicity to human cells. LSD1-IN-44 can be used for schistosomiasis research .
Cat. No.: HY-101725A
CAS No.: 86630-81-1
Synonyms: Ro 11-3624; Ro 11-3624/001
(R)-Meclonazepam (Ro 11-3624) is an inactive enantiomer of Meclonazepam. Meclonazepam is a benzodiazepine derivative with anti-schistosomiasis activities .
Cat. No.: HY-161596
SmCB1-IN-1 (Compound 2h) is an inhibitor for S. mansoni cathepsin B1 (SmCB1) with an Ki of 0.05 μM . SmCB1-IN-1 exhibits selectivity toward human off-target cathepsins (29% and 37% inhibition for CatB and CatL at 20 μM). SmCB1-IN-1 inhibits 68% Schistosoma mansoni at 1 μM .
Cat. No.: HY-B0244R
CAS No.: 55268-74-1
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Praziquantel (Standard) is the analytical standard of Praziquantel. This product is intended for research and analytical applications. Praziquantel is a broadly effective trematocide and cestocide, the initial effect of praziquantel on the schistosome may be an interaction of the drug with lipid constituents of the tegumental membrane. Praziquantel is used for the research of schistosomiasis .
Cat. No.: HY-151433
CAS No.: 2138480-87-0
Antiparasitic agent-10 (Compound 94) is an anti-parasitic agent, shows anti-schistosomal activity. Antiparasitic agent-10 shows activity against adults of Schistosoma mansoni, and can be used in Schistosomiasis research .
Cat. No.: HY-168547S
CAS No.: 3021566-15-1
HDAC8-IN-8 (15a) is an HDAC8 inhibitor, with IC50 values of 23.9 μM and 268.2 μM for hHDAC8 and smHDAC8 respectively. And for hHDAC1 and hHDAC6, the IC50 values are 12.1 μM and 2.9 μM respectively. HDAC8-IN-8 can be used in schistosomiasis-related research .
Cat. No.: HY-175185
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MC3935 is a LSD1 inhibitor with an IC50 of 0.52 μM for LSD1-CoREST enzymatic complex. MC3935 has significant antischistosomal activity against transformed schistosomula (NTS) and Schistosoma mansoni adult worms while showing a delayed onset of action towards juvenile forms. MC3935 has no significant toxicity to human cells. MC3935 can be used for schistosomiasis research .
Cat. No.: HY-144098
CAS No.: 2824131-20-4
HDAC8-IN-2 (compound 5o) is a potent HDAC8 inhibitor, with IC50 values of 0.27 and 0.32 μM for smHDAC8 (Schistosoma mansoni histone deacetylase 8) and hHDAC8, respectively. HDAC8-IN-2 shows significant killing of the schistosome larvae. HDAC8-IN-2 markedly impairs egg laying of adult worm pairs .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
