2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. Tetrahydro-β-carboline

Tetrahydro-β-carboline  (Synonyms: Tryptoline)

製品番号: HY-20696 純度: 99.40%
COA 取扱説明書 Technical Support

Tetrahydro-β-carboline (Tryptoline) is a metabolite of tryptamine, also is a competitive serotonin reuptake inhibitor with an Ki value of 6.1 µM.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

Tetrahydro-β-carboline

Tetrahydro-β-carboline 構造式

CAS 番号 : 16502-01-5

容量 価格（税別） 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 27 在庫あり
Solution
10 mM * 1 mL in DMSO USD 27 在庫あり
Solid
1 g $25 在庫あり
5 g $40 在庫あり
10 g $60 在庫あり
50 g   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 0 publication(s) in Google Scholar

Other Forms of Tetrahydro-β-carboline:

Tetrahydro-β-carboline 関連抗体

Top Publications Citing Use of Products

5-HT Receptor アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示
5-HT Receptor 5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor

  • 生物活性

  • 純度とドキュメンテーション

  • 参考文献

  • カスタマーレビュー

製品説明

Tetrahydro-β-carboline (Tryptoline) is a metabolite of tryptamine, also is a competitive serotonin reuptake inhibitor with an Ki value of 6.1 µM[1].

IC50 & Target[1]

serotonin

6.1 μM (Ki)

体内実験

Tetrahydro-β-carboline (20 µg; i.c.v.) increases the serotonin levels in the same part of the brain in rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 180-200g female Sprague-Dawley rats[1]
Dosage: 20 µg
Administration: Intraventricular injection
Result: Increased of serotonin levels in the same part of the brain whereas the monoamine oxidase activity was not altered.
分子量

172.23

分子式

C11H12N2
CAS 番号
Appearance

Solid

Color

Light yellow to brown

SMILES

C1(NC2=C3CCNC2)=C3C=CC=C1
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
体外: 

DMSO : 100 mg/mL (580.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.8062 mL 29.0309 mL 58.0619 mL
5 mM 1.1612 mL 5.8062 mL 11.6124 mL
10 mM 0.5806 mL 2.9031 mL 5.8062 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション

純度: 99.40%

COA (251 KB) HNMR (131 KB) RP-HPLC (234 KB) LCMS (98 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.8062 mL 29.0309 mL 58.0619 mL 145.1547 mL
5 mM 1.1612 mL 5.8062 mL 11.6124 mL 29.0309 mL
10 mM 0.5806 mL 2.9031 mL 5.8062 mL 14.5155 mL
15 mM 0.3871 mL 1.9354 mL 3.8708 mL 9.6770 mL
20 mM 0.2903 mL 1.4515 mL 2.9031 mL 7.2577 mL
25 mM 0.2322 mL 1.1612 mL 2.3225 mL 5.8062 mL
30 mM 0.1935 mL 0.9677 mL 1.9354 mL 4.8385 mL
40 mM 0.1452 mL 0.7258 mL 1.4515 mL 3.6289 mL
50 mM 0.1161 mL 0.5806 mL 1.1612 mL 2.9031 mL
60 mM 0.0968 mL 0.4838 mL 0.9677 mL 2.4192 mL
80 mM 0.0726 mL 0.3629 mL 0.7258 mL 1.8144 mL
100 mM 0.0581 mL 0.2903 mL 0.5806 mL 1.4515 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Tetrahydro-β-carboline Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tetrahydro-β-carboline16502-01-5Tryptoline5-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorInhibitorinhibitorinhibit

最近チェックした製品:

オンラインお問い合わせ

Your information is safe with us. * Required Fields.

製品名

  

カスタマ需要量 *

お名前 *

 

タイトル

メールアドレス *

 

電話番号 *

デパートメント

 

組纖名 *

市区町村

都道府県

国或いは地域 *

      

必ず会社名を記載ください。個人への返信は行いません。

備考

バルクお問い合わせ

Inquiry Information

製品名:
Tetrahydro-β-carboline
製品番号:
HY-20696
数量:
MCE 日本正規代理店:

カスタマーレビュー

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

製品名

  

Lot #

お名前 *

 

メールアドレス *

電話番号 *

 

部門 *

組纖名 *

 

国或いは地域 *

備考

Request for HNMR Report

We have received your request and will respond to you as soon as possible.