1. Anti-infection
    Membrane Transporter/Ion Channel
  2. Parasite
    Sodium Channel
  3. λ-Cyhalothrin

λ-Cyhalothrin 

Cat. No.: HY-B0836
Handling Instructions

λ-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group. λ-Cyhalothrin is used to control a wide range of pests in a variety of applications. λ-Cyhalothrin is a neurotoxin that targets sodium channels in the membranes of neurons in the central nervous system.

For research use only. We do not sell to patients.

λ-Cyhalothrin Chemical Structure

λ-Cyhalothrin Chemical Structure

CAS No. : 91465-08-6

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Description

λ-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group. λ-Cyhalothrin is used to control a wide range of pests in a variety of applications. λ-Cyhalothrin is a neurotoxin that targets sodium channels in the membranes of neurons in the central nervous system[1].

In Vitro

The mechanism of λ-Cyhalothrin toxicity produces delay in sodium channel inactivation, which leads to persistent depolarization of the nerve membrane. λ-Cyhalothrin produces membrane depolarization, calcium ion infl ux, and neurotransmitter release from rat brain synaptosomes[1].
λ-Cyhalothrin possesses estrogenic properties and has an ability to function as a xenoestrogen promoting human breast carcinoma cell proliferation in vitro[1].
λ-Cyhalothrin has found multiple uses in pest (fleas, cockroaches, flies, and ants) control[1].
λ-Cyhalothrin is highly effective against the malaria transmitting species of Anopheles[1].

In Vivo

The effect of λ-Cyhalothrin (i.p.) on memory, movement activity, and co-ordination in mice exposed to bilateral clamping of the carotid arteries (BCCA) is investigated. Neither memory nor movement co-ordination are impaired by BCCA or λ-Cyhalothrin. Exploratory locomotor activity is significantly reduced in the BCCA/LCH group. Spontaneous movement activity is significantly reduced in the BCCA/λ-Cyhalothrin group . Exposure to λ-Cyhalothrin coexisting with BCCA decreases motor activity in the mice in 2 subsequent 30-min[1].

Molecular Weight

449.85

Formula

C₂₃H₁₉ClF₃NO₃

CAS No.

91465-08-6

SMILES

O=C([[email protected]@H]1C(C)(C)[[email protected]@H]1/C=C(Cl)/C(F)(F)F)O[[email protected]@H](C#N)C2=CC=CC(OC3=CC=CC=C3)=C2

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

λ-CyhalothrinParasiteSodium ChannelNa channelsNa+ channelsInsecticidepyrethroidchoreoatetosissalivationα-cyanoneurotoxinpesticideacaricidedepolarizationInhibitorinhibitorinhibit

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λ-Cyhalothrin
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HY-B0836
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