1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. 6-Oxohexanoic acid

6-Oxohexanoic acid 

Cat. No.: HY-141595
Handling Instructions

6-Oxohexanoic acid is a non-cleavable modified MMAF-C5-COOH linker and can be used in the synthesis of modified MMAF-C5-COOH, a drug-linker conjugate for ADC.

For research use only. We do not sell to patients.

6-Oxohexanoic acid Chemical Structure

6-Oxohexanoic acid Chemical Structure

CAS No. : 928-81-4

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Description

6-Oxohexanoic acid is a non-cleavable modified MMAF-C5-COOH linker and can be used in the synthesis of modified MMAF-C5-COOH, a drug-linker conjugate for ADC[1].

In Vitro

MMAF inhibits anaplastic large cell lymphoma Karpas 299, breast carcinoma H3396, renal cell carcinoma 786-O and Caki-1 cells with IC50s of 119, 105, 257 and 200 nM in vitro cytotoxicity assay[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

130.14

Formula

C₆H₁₀O₃

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Product Name:
6-Oxohexanoic acid
Cat. No.:
HY-141595
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