2. GPCR/G Protein
  3. GLP Receptor GCGR
  4. SAR441255

SAR441255 is a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist. SAR441255 displays high potency with balanced activation of all three target receptors.?SAR441255 shows positive acute glucoregulatory effectss in diabetic obese monkeys.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

SAR441255 Chemical Structure

SAR441255 Chemical Structure

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SAR441255 Related Antibodies

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Description

SAR441255 is a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist. SAR441255 displays high potency with balanced activation of all three target receptors.?SAR441255 shows positive acute glucoregulatory effectss in diabetic obese monkeys[1].

IC50 & Target

IC50: GLP-1/GIP/GCG receptor[1]
Molecular Weight

4866.56

Formula

C225H3555N57O63
Sequence Shortening

H-{Aib}-HGTFTSDLSKL-{Lys(γGlu-γGlu-Palm acid)}-EEQRQ-{Aib}-EFIEWLKA-{d-Ala}-GPPS-{Aib}-KPPPK-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SAR441255 Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SAR441255SAR 441255SAR-441255GLP ReceptorGCGRGlucagon ReceptorGlucagonmetabolic diseaseobesitytype 2 diabetemonkeyInhibitorinhibitorinhibit

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HY-P10031
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