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Cat. No.: HY-P11759

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Myr-transportan-Cys

Name: Myr-transportan-Cys
Brand: MedChemExpress
SKU: HY-P11759
Availability: PreOrder

Myr-transportan-Cys is a derivative of the cell-penetrating peptide Transportan (HY-P1732), and its conjugated myristoyl group (Myr) enhances the interaction between the peptide and cell membranes. Myr-transportan-Cys integrates three key delivery functions: nucleic acid condensation, cell penetration, and endosomal escape. Myr-transportan-Cys can form immunostimulatory tandem peptide nanocomplexes (iTPNCs) for encapsulating and delivering immunostimulatory oligonucleotide cargos to tumors.

For research use only. We do not sell to patients.

Formula: C₁₅₁H₂₅₇N₃₅O₃₅S
Molecular Weight:3154.93

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Custom Peptide Synthesis

Myr-transportan-Cys Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
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Biological Activity

Description

In Vitro

Through modular assembly with targeting peptides (e.g., iRGD) and stabilizing polymers (PEG), Myr-transportan-Cys can construct advanced nanodelivery platforms for tumor-specific gene silencing and enhanced immune checkpoint inhibitor therapy^[1]^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 3154.93
Formula C₁₅₁H₂₅₇N₃₅O₃₅S
Sequence

{myristic acid-Gly}-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Lys-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-Cys
Sequence Shortening

{myristic acid-Gly}-WTLNSAGYLLGKINLKALAALAKKILC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Kwon EJ, et al. Peptide Spiders: Peptide-Polymer Conjugates to Traffic Nucleic Acids. Mol Pharm. 2020;17(9):3633-3642. [Content Brief]

[2]. Buss CG, et al. Nanoparticle delivery of immunostimulatory oligonucleotides enhances response to checkpoint inhibitor therapeutics. Proc Natl Acad Sci U S A. 2020;117(24):13428-13436. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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