1. GPCR/G Protein
  2. Glucagon Receptor
  3. Liraglutide


Cat. No.: HY-P0014 Purity: 99.71%
Handling Instructions

Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus.

For research use only. We do not sell to patients.

Liraglutide Chemical Structure

Liraglutide Chemical Structure

CAS No. : 204656-20-2

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1 mg USD 144 In-stock
Estimated Time of Arrival: December 31
5 mg USD 600 In-stock
Estimated Time of Arrival: December 31
10 mg USD 1080 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 5 publication(s) in Google Scholar

Top Publications Citing Use of Products

    Liraglutide purchased from MCE. Usage Cited in: Mol Med Rep. 2016 Oct;14(4):3662-8.

    Effects of Liraglutide treatment on Alp and OC protein expression levels, and matrix mineralization. Following culture in commercial osteogenic differentiation medium for 14 days, MC3T3-E1 cells are cultured for an additional 14 days in basal culture medium with various concentrations of Liraglutide (0, 0.1, 0.5, 1, 2 and 4 nM). MC3T3-E1 cells maintained in DMEM for 28 days with no treatment are used as the NC; cells cultured in the commercial osteogenic differentiation medium for 14 days and in
    • Biological Activity

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    • Customer Review


    Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus.

    IC50 & Target

    GLP-1 receptor[1]

    In Vitro

    Liraglutide binds to the same receptors as does the endogenous metabolic hormone GLP-1. Liraglutide is an injectable drug for the treatment of type 2 diabetes, also can be used to treat obesity in adults with some related comorbidity. Liraglutide activated AMPK/SREBP1 pathway in oxLDL-stimulated Raw264.7 cells[1].

    Clinical Trial
    Molecular Weight




    CAS No.




    Sequence Shortening





    Room temperature in continental US; may vary elsewhere.

    Protect from light
    Powder -80°C 2 years
      -20°C 1 year
    In solvent -80°C 6 months
      -20°C 1 month
    Solvent & Solubility
    In Vitro: 

    H2O : 5 mg/mL (1.33 mM; ultrasonic and adjust pH to 8 with NaOH)

    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 0.2666 mL 1.3329 mL 2.6658 mL
    5 mM --- --- ---
    10 mM --- --- ---
    *Please refer to the solubility information to select the appropriate solvent.
    Cell Assay

    Raw264.7 macrophage cells are cultured in Dulbecco's modified Eagle's medium supplemented with 10% fetal bovine serum in a humidified 37°C incubator with 5% CO2. The cells are incubated with oxLDL (50 μg/mL), Liraglutide (0.1, 0.5, 1 and 2 nM) or Exendin-3 (9-39) (1, 10 and 100 nM) alone, or in combination[1].

    MCE has not independently confirmed the accuracy of these methods. They are for reference only.


    Purity: 99.71%

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    LiraglutideGlucagon ReceptorGCGRInhibitorinhibitorinhibit

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