2. GPCR/G Protein
  3. Vasopressin Receptor
  4. (d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin

(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin  (Synonyms: SKF 100273)

Cat. No.: HY-P1162
SDS
Handling Instructions Technical Support

(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin (SKF 100273) is a vasopressin V1 receptor selective antagonist.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Custom Peptide Synthesis

(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin

(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin 화학구조

CAS No. : 73168-24-8

사이즈 가격 재고 수량
1 mg 견적 받기 3 - 4 Weeks 4 - 5 weeks 5 - 6 weeks 2 - 3 weeks
5 mg   견적 받기  
10 mg   견적 받기  
Synthetic products have potential research and development risk.

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This product is a controlled substance and not for sale in your territory.

(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin Related Antibodies

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V1a Receptor  V1b Receptor  V2 Receptor 

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin (SKF 100273) is a vasopressin V1 receptor selective antagonist[1].

Cellular Effect
Cell Line Type Value Description References
CHO IC50
9.9 x 10-10 M
Compound: [d(CH2)51,Tyr(Me)2]-AVP
Displacement of [3H]AVP from human recombinant V1a receptor expressed in CHO cells measured after 60 mins by scintillation counting method
Displacement of [3H]AVP from human recombinant V1a receptor expressed in CHO cells measured after 60 mins by scintillation counting method
[PMID: 27876250]
CHO IC50
9.9 x 10-10 M
Compound: [d(CH2)51.Tyr(Me)2]-AVP
Displacement of [3H]AVP from human recombinant arginine vasopressin receptor 1a expressed in CHO cells
Displacement of [3H]AVP from human recombinant arginine vasopressin receptor 1a expressed in CHO cells
[PMID: 26988801]
분자량

1151.36

화학식

C52H74N14O12S2
CAS No.
Sequence

{Pmp}-{Tyr(Me)}-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bond: Pmp1-Cys6) (Pmp=β-Mercapto-β,β-cyclopentamethylene-propionic acid)
Sequence Shortening

{Pmp}-{Tyr(Me)}-FQNCPRG-NH2 (Disulfide bond: Pmp1-Cys6) (Pmp=β-Mercapto-β,β-cyclopentamethylene-propionic acid)
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
용액&용해도
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
순도&문서
References
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(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin Related Classifications

  • 몰농도 계산기

  • 농도 희석 계산기

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin73168-24-8SKF 100273SKF100273SKF-100273Vasopressin ReceptorInhibitorinhibitorinhibit

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상품명:
(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin
Cat. No.:
HY-P1162
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