Other disease

Other disease (35):

Cat. No.	Product Name	CAS No.	Purity	Chemical Structure

Melatonin	73-31-4	99.93%
Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties. Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation. Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress.

β-Nicotinamide mononucleotide	1094-61-7	99.68%
β-nicotinamide mononucleotide (β-NM) is a product of the nicotinamide phosphoribosyltransferase (NAMPT) reaction and a key NAD⁺ intermediate. The pharmacological activities of β-nicotinamide mononucleotide include its role in cellular biochemical functions, cardioprotection, diabetes, Alzheimer's disease, and complications associated with obesity.

HY-N0437

Progesterone 57-83-0 99.42%

Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
HY-76847

Chenodeoxycholic Acid 474-25-9 ≥98.0%

Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.

Progesterone	57-83-0	99.42%
Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

Chenodeoxycholic Acid	474-25-9	≥98.0%
Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.

Cholic acid	81-25-4	≥98.0%
Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active.

HY-32351

Calcifediol 19356-17-3 99.94%

Calcifediol (25-hydroxy Vitamin D3), a major circulating metabolite of vitamin D3, is a potent VDR inhibitor.

Calcifediol	19356-17-3	99.94%
Calcifediol (25-hydroxy Vitamin D3), a major circulating metabolite of vitamin D3, is a potent VDR inhibitor.

Trimethylamine N-oxide	1184-78-7	≥98.0%
Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide induces inflammation by activating the ROS/NLRP3 inflammasome. Trimethylamine N-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway.

HY-W050026

Phenylacetylglutamine 28047-15-6 99.02%

Phenylacetylglutamine is a colonic microbial metabolite from amino acid fermentation.

Phenylacetylglutamine	28047-15-6	99.02%
Phenylacetylglutamine is a colonic microbial metabolite from amino acid fermentation.

SDMA	30344-00-4	≥98.0%
SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide (NO) synthase activity. SDMA, a novel kidney biomarker, permits earlier diagnosis of kidney disease than traditional creatinine testing.

Pseudouridine	1445-07-4	99.93%
Pseudouridine is an isomer of the nucleoside uridine, and the most abundant modified nucleoside in non-coding RNAs. Pseudouridine in rRNA and tRNA can fine-tune and stabilize the regional structure and help maintain their functions in mRNA decoding, ribosome assembly, processing and translation.

Oxaloacetic acid	328-42-7	99.88%
Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis.

HY-W011540

8-Hydroxy-2'-deoxyguanosine 88847-89-6

8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis.
HY-113136

1-Methylguanosine 2140-65-0 98.39%

1-Methylguanosine is a methylated nucleoside originating from RNA degradation. 1-Methylguanosine is a tumour marker.
HY-Y0511

N-Methylsarcosine 1118-68-9 ≥98.0%

N-Methylsarcosine is an amino acid building block for protein, found in a small amount in the body.
HY-113137

N2,N2-Dimethylguanosine 2140-67-2 99.29%

N2,N2-Dimethylguanosine is an urinary nucleoside, a primary degradation product of tRNA.
HY-113283

Homogentisic acid 451-13-8 99.06%

Homogentisic acid is a specific metabolite in urine and serum, which is used for diagnosis of alkaptonuria.
HY-113328

Aminoadipic acid 542-32-5 ≥98.0%

Aminoadipic acid is an intermediate in the metabolism of lysine and saccharopine.
HY-113139

1-Methylinosine 2140-73-0 99.96%

1-Methylinosine is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA.

8-Hydroxy-2'-deoxyguanosine	88847-89-6
8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis.

1-Methylguanosine	2140-65-0	98.39%
1-Methylguanosine is a methylated nucleoside originating from RNA degradation. 1-Methylguanosine is a tumour marker.

N-Methylsarcosine	1118-68-9	≥98.0%
N-Methylsarcosine is an amino acid building block for protein, found in a small amount in the body.

N2,N2-Dimethylguanosine	2140-67-2	99.29%
N2,N2-Dimethylguanosine is an urinary nucleoside, a primary degradation product of tRNA.

Homogentisic acid	451-13-8	99.06%
Homogentisic acid is a specific metabolite in urine and serum, which is used for diagnosis of alkaptonuria.

Aminoadipic acid	542-32-5	≥98.0%
Aminoadipic acid is an intermediate in the metabolism of lysine and saccharopine.

1-Methylinosine	2140-73-0	99.96%
1-Methylinosine is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA.

Glycitein	40957-83-3	98.03%
Glycitein is a soybean (yellow cultivar) isoflavonoid; used in combination with other isoflavonoids such as genistein and daidzein to study apoptosis and anti-oxidation processes.

HY-W052144

(±) Anabasine 13078-04-1

(±) Anabasine is a biphasic muscle relaxant.

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