1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. N-Acetyl-L-aspartic acid

N-Acetyl-L-aspartic acid is a derivative of aspartic acid.

For research use only. We do not sell to patients.

N-Acetyl-L-aspartic acid Chemical Structure

N-Acetyl-L-aspartic acid Chemical Structure

CAS No. : 997-55-7

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Solid + Solvent
10 mM * 1 mL in DMSO
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Based on 1 publication(s) in Google Scholar

Other Forms of N-Acetyl-L-aspartic acid:

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  • Purity & Documentation

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Description

N-Acetyl-L-aspartic acid is a derivative of aspartic acid.

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

175.14

Formula

C6H9NO5

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)C[C@@H](C(O)=O)NC(C)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

H2O : 62.5 mg/mL (356.86 mM; Need ultrasonic)

DMSO : 5 mg/mL (28.55 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.7097 mL 28.5486 mL 57.0972 mL
5 mM 1.1419 mL 5.7097 mL 11.4194 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 12.5 mg/mL (71.37 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.45%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 5.7097 mL 28.5486 mL 57.0972 mL 142.7429 mL
5 mM 1.1419 mL 5.7097 mL 11.4194 mL 28.5486 mL
10 mM 0.5710 mL 2.8549 mL 5.7097 mL 14.2743 mL
15 mM 0.3806 mL 1.9032 mL 3.8065 mL 9.5162 mL
20 mM 0.2855 mL 1.4274 mL 2.8549 mL 7.1371 mL
25 mM 0.2284 mL 1.1419 mL 2.2839 mL 5.7097 mL
H2O 30 mM 0.1903 mL 0.9516 mL 1.9032 mL 4.7581 mL
40 mM 0.1427 mL 0.7137 mL 1.4274 mL 3.5686 mL
50 mM 0.1142 mL 0.5710 mL 1.1419 mL 2.8549 mL
60 mM 0.0952 mL 0.4758 mL 0.9516 mL 2.3790 mL
80 mM 0.0714 mL 0.3569 mL 0.7137 mL 1.7843 mL
100 mM 0.0571 mL 0.2855 mL 0.5710 mL 1.4274 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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N-Acetyl-L-aspartic acid Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
N-Acetyl-L-aspartic acid
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HY-113524
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