1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite

Isospaglumic acid (Synonyms: N-Acetylaspartylglutamic acid; NAAG; α-Spaglumic acid)

Cat. No.: HY-100921
Handling Instructions

Isospaglumic acid is a neuropeptide found in millimolar concentrations in brain.

For research use only. We do not sell to patients.

Isospaglumic acid Chemical Structure

Isospaglumic acid Chemical Structure

CAS No. : 3106-85-2

Size Price Stock
10 mg USD 60 Get quote
50 mg USD 120 Get quote

* Please select Quantity before adding items.

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Isospaglumic acid is a neuropeptide found in millimolar concentrations in brain.

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Isospaglumic acid (N-Acetylaspartylglutamate; NAAG) is released upon depolarization by a Ca2+-dependent process and is an agonist at mGluR3 receptors and an antagonist at NMDA receptors. NAAG is catabolized to N-acetylaspartate and glutamate primarily by glutamate carboxypeptidase II, which is expressed on the extracellular surface of astrocytes. The levels of NAAG and the activity of carboxypeptidase II are altered in a regionally specific fashion in several neuropsychiatric disorders[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2868 mL 16.4339 mL 32.8677 mL
5 mM 0.6574 mL 3.2868 mL 6.5735 mL
10 mM 0.3287 mL 1.6434 mL 3.2868 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

304.25

Formula

C₁₁H₁₆N₂O₈

CAS No.

3106-85-2

SMILES

O=C(O)CC[[email protected]@H](C(O)=O)NC([[email protected]](CC(O)=O)NC(C)=O)=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Isospaglumic acid
Cat. No.:
HY-100921
Quantity:

Isospaglumic acid

Cat. No.: HY-100921