1. Metabolic Enzyme/Protease
    Anti-infection
  2. Cytochrome P450
    Fungal
  3. Tebuconazole

Tebuconazole 

Cat. No.: HY-B0852 Purity: 99.38%
Handling Instructions

Tebuconazole is an agricultural azole fungicide which can also inhibit CYP51 with IC50s of 0.9 and 1.3 μM for Candida albicans CYP51 (CaCYP51) and truncated Homo sapiens CYP51 (Δ60HsCYP51), respectively.

For research use only. We do not sell to patients.

Tebuconazole Chemical Structure

Tebuconazole Chemical Structure

CAS No. : 107534-96-3

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
200 mg USD 60 In-stock
Estimated Time of Arrival: December 31
1 g USD 108 In-stock
Estimated Time of Arrival: December 31
5 g   Get quote  
10 g   Get quote  

* Please select Quantity before adding items.

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Based on 1 publication(s) in Google Scholar

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Description

Tebuconazole is an agricultural azole fungicide which can also inhibit CYP51 with IC50s of 0.9 and 1.3 μM for Candida albicans CYP51 (CaCYP51) and truncated Homo sapiens CYP51 (Δ60HsCYP51), respectively.

IC50 & Target

IC50: 0.9 μM (CaCYP51), 1.3 μM (Δ60HsCYP51)[1]

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 50 mg/mL (162.43 mM)

H2O : < 0.1 mg/mL (insoluble)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2487 mL 16.2433 mL 32.4865 mL
5 mM 0.6497 mL 3.2487 mL 6.4973 mL
10 mM 0.3249 mL 1.6243 mL 3.2487 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (8.12 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (8.12 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (8.12 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
Molecular Weight

307.82

Formula

C₁₆H₂₂ClN₃O

CAS No.

107534-96-3

SMILES

CC(C)(C)C(O)(CCC1=CC=C(Cl)C=C1)CN2C=NC=N2

Shipping

Room temperature in continental US; may vary elsewhere

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Tebuconazole
Cat. No.:
HY-B0852
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Tebuconazole

Cat. No.: HY-B0852