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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
38 Results for "
Glycogen phosphorylase
" in MedChemExpress (MCE) Product Catalog:
Products (38)
38 Results for "Glycogen phosphorylase" in MCE Product Catalog:
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13 Publications Verification
Synonyms: NSC 113939; 5-ITu
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5-Iodotubercidin (NSC 113939), an ATP mimetic, is a potent adenosine kinase inhibitor with an IC50 of 26 nM. 5-Iodotubercidin (NSC 113939) initiates glycogen synthesis in isolated hepatocytes by causing inactivation of phosphorylase and activation of glycogen synthase. 5-Iodotubercidin (NSC 113939) also inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2, PKC and Haspin .
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8 Cited Publications
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CP-91149 is a GP (glycogen phosphorylase) inhibitor. CP-91149 promotes glycogen resynthesis, but not its overaccumulation. CP-91149 has the potential for Type II (insulin-dependent) diabetes study .
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Ingliforib (CP 368296) is a glycogen phosphorylase inhibitor, with IC50s of 52, 352 and 150 nM for liver, muscle and brain glycogen phosphorylase, and has cardioprotective activity.
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Metabolic Disease Endogenous metabolite Disease Research Fields Sweeteners Saccharides Food Research Monosaccharides
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Synonyms: GPi 819
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Cardiovascular Disease Neurological Disease Metabolic Disease
CP-316819 (GPi 819) is a blood-brain barrier permeable glycogen phosphorylase inhibitor. CP-316819 inhibits hepatic glycogenolysis, safely reduces blood glucose in type 2 diabetes, and rarely induces hypoglycemia. CP-316819 increases brain glycogen reserves, protects neurons, alleviates hypoglycemic brain injury, and inhibits excessive platelet activation, exerting both neuroprotective and vasculoprotective effects. CP-316819 can be used in research related to hypoglycemia, thrombosis, autoimmune inflammatory diseases, and type 2 diabetes .
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Triterpenes Terpenoids Cucurbitaceae Metabolic Disease Plants Bolbostemma paniculaum (Maxim)Franguet Disease Research Fields
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Phosphorylase a, rabbit muscle is glycogen phosphorylase isolated from rabbit muscle. Phosphorylase a, rabbit muscle catalyzes glycogenolysis, converting glycogen and inorganic phosphate into glucose-1-phosphate to supply energy for muscle contraction .
Cat. No.: HY-P3570
CAS No.: 98968-94-6
Synonyms: Lom-AKH-II
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Cat. No.: HY-15424R
CAS No.: 24386-93-4
Synonyms: NSC 113939 (Standard); 5-ITu (Standard)
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5-Iodotubercidin (Standard) is the analytical standard of 5-Iodotubercidin. This product is intended for research and analytical applications. 5-Iodotubercidin (NSC 113939), an ATP mimetic, is a potent adenosine kinase inhibitor with an IC50 of 26 nM. 5-Iodotubercidin (NSC 113939) initiates glycogen synthesis in isolated hepatocytes by causing inactivation of phosphorylase and activation of glycogen synthase. 5-Iodotubercidin (NSC 113939) also inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2, PKC and Haspin .
Cat. No.: HY-113585
CAS No.: 100991-92-2
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1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride is a naturally occurring pyrrolidine alkaloid that acts as an inhibitor of glycogen phosphorylase and α-glucosidases, and is sourced from Arachniodes standishii and Angylocalyx boutiqueanus.
Cat. No.: HY-I0210S
CAS No.: 233600-80-1
Cat. No.: HY-P3572
CAS No.: 61627-67-6
Synonyms: Lom-AKH-I
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Cat. No.: HY-128029
CAS No.: 648926-15-2
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Glycogen phosphorylase-IN-1 (Compound 42) is an inhibitor for human liver glycogen phosphorylase (hlGPa) and hepatocyte glycogen-derived glucose production with IC50s of 53 and 380 nM, respectively. Glycogen phosphorylase-IN-1 reveals efficacy towards type 2 diabetes .
Cat. No.: HY-172805
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Glycogen phosphorylase-IN-2 (compound 9C) is an inhibitor of glycogen phosphorylase with a Ki value of 1.9 nM and an IC50 value of 4 nM .
Cat. No.: HY-108614
CAS No.: 918902-32-6
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GPi688 is a potent and orally active glycogen phosphorylase (GPa) inhibitor with IC50s of 19 nM, 61 nM and 12 nM for human liver GPa, rat liver GPa and human skeletal muscle GPa, respectively . GPi688 can inhibit glucagons-mediated glucose output in rat primary hepatocytes. GPi688 can be used for researching glucagon-mediated hyperglycaemia .
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Cat. No.: HY-117172
CAS No.: 186430-23-9
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CP320626 is a potent inhibitor of human liver glycogen phosphorylase (IC50=205 nM). CP320626 reduces blood glucose in diabetic mice without changing plasma insulin levels. CP320626 can be used in the study of type 2 diabetes .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
