PYGM Antibody (YA7986)
(Synonyms: glycogen; glycogen phosphorylase; glycogen storage disease type V; glycogen storage disease type V); McArdle syndrome; muscle; muscle (McArdle syndrome; myophosphorylase; phosphorylase)PYGM Antibody (YA7986) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PYGM.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Rat, Mouse
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:1000-4000 | 1:2000-2500 |
Product Details
PYGM Antibody (YA7986) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PYGM.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Rat, Mouse
Human recombinant protein fragment corresponding to amino acids 698-842 of human PYGM produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PYGM is an Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis
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Isoforms & Post-Translational Modification
P11217 has two isomers: P11217-1: 97092 Da (predicted); P11217-2: 87317 Da (predicted).
Phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A -
Subunit
Homodimer (PubMed:1150650, PubMed:16523484)
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SwissProt ID
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Synonyms
glycogen; glycogen phosphorylase; glycogen storage disease type V; glycogen storage disease type V); McArdle syndrome; muscle; muscle (McArdle syndrome; myophosphorylase; phosphorylase
Documentation
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