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Results for "

Melanocortin+Receptor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	COX (6) ERK (7) Isotope-Labeled Compounds (1) Melanocortin Receptor (35) Reference Standards (3)
By Research Areas:	Cancer (4) Cardiovascular Disease (1) Endocrinology (9) Inflammation/Immunology (13) Metabolic Disease (15) Neurological Disease (8)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

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Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P0252

α-MSH Maximum Cited Publications 23 Publications Verification α-Melanocyte-Stimulating Hormone	Melanocortin Receptor	Neurological Disease Metabolic Disease Inflammation/Immunology
α-MSH (α-Melanocyte-Stimulating Hormone), an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH is a post-translational derivative of pro-opiomelanocortin (POMC) .

HY-P1211

Adrenocorticotropic Hormone (ACTH) (1-39), human 1-39-Corticotropin (human)	Melanocortin Receptor	Metabolic Disease
Adrenocorticotropic Hormone (ACTH) (1-39), human is a *melanocortin receptor* agonist.

HY-P0267

Melanotan (MT)-II 1 Publications Verification	Melanocortin Receptor	Neurological Disease
Melanotan (MT)-II, a synthetic *melanocortin* receptor agonist, is an injectable peptide hormone used to promote tanning.

HY-B1456A

Fenoprofen 2 Publications Verification LILLY-53858	COX Melanocortin Receptor ERK	Inflammation/Immunology
Fenoprofen (LILLY-53858) is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits cyclooxygenase (COX). Fenoprofen is a melanocortin receptors (MCRs) positive allosteric modulator (PAM). Fenoprofen also increases ERK1/2 activation in HEK293T cells. Fenoprofen has anti-arthritic activities and can be used for the study of rheumatoid arthritis and osteoarthritis .

HY-N2466

Melanotan I 1 Publications Verification MT-I; [Nle4,D-Phe7]-α-MSH	Melanocortin Receptor	Neurological Disease Cancer
Melanotan I is a potent non-selective melanocortin receptor (MCR) agonist. Melanotan I is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH) that stimulates melanogenesis. Melanotan I can induce skin tanning by mimicking the actions of a-MSH on the melanocortin type 1 receptors (MC1R) of melanocytes. Melanotan I can be used for the research of sun-induced skin cancer, melanoma, inflammation and male erectile dysfunction .

HY-18678A

Bremelanotide Acetate 1 Publications Verification PT-141 Acetate	Melanocortin Receptor	Metabolic Disease
Bremelanotide (PT-141) Acetate is a *melanocortin receptor* agonist. Bremelanotide Acetate can activate MC4R and increases dopamine release. Bremelanotide Acetate induces appetitive sexual behaviors, female mounting behavior, and repetitive self-grooming. Bremelanotide Acetate can be used for the research of hypoactive sexual desire disorders .

HY-P5971

TCMCB07 Mifomelatide	Melanocortin Receptor	Neurological Disease Metabolic Disease
TCMCB07, a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 plays an important role in cachexia. TCMCB07 has potential transport capabilities .

HY-18678

Bremelanotide 1 Publications Verification PT-141	Melanocortin Receptor	Neurological Disease Metabolic Disease
Bremelanotide (PT-141) is a *melanocortin receptor* agonist. Bremelanotide can activate MC4R and increases dopamine release. Bremelanotide induces appetitive sexual behaviors, female mounting behavior, and repetitive self-grooming. Bremelanotide can be used for the research of hypoactive sexual desire disorders .

HY-107139

JNJ-10229570	Melanocortin Receptor	Endocrinology
JNJ-10229570 is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the production of sebum-specific lipids. JNJ-10229570 inhibits the binding of ¹²⁵I-NDP-α-MSH to cells expressing human MC1R and MC5R, with IC₅₀ values of 270 nM and 200 nM, respectively.

HY-118930A

MK-0493 hydrochloride	Melanocortin Receptor	Metabolic Disease Endocrinology
MK-0493 hydrochloride is a potent, orally active and selective agonist of the melanocortin receptor 4 (MC4R), demonstrating significant reductions in energy intake .

HY-147301A

Resomelagon acetate AP1189 acetate	Melanocortin Receptor	Metabolic Disease Inflammation/Immunology
Resomelagon (AP1189) acetate is a potent, orally active melanocortin receptor (MR) agonist about MC₁ and MC₃. Resomelagon acetate induces ERK1/2 phosphorylation and Ca ²⁺ mobilization. Resomelagon acetate has anti-inflammatory activity. Resomelagon acetate can be used for obesity and chronic inflammation research .

HY-P0252A

α-MSH TFA Maximum Cited Publications 23 Publications Verification α-Melanocyte-Stimulating Hormone TFA	Melanocortin Receptor	Neurological Disease Metabolic Disease Inflammation/Immunology
α-MSH (α-Melanocyte-Stimulating Hormone) TFA, an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH TFA is a post-translational derivative of pro-opiomelanocortin (POMC) .

HY-147301

Resomelagon AP1189	Melanocortin Receptor	Metabolic Disease Inflammation/Immunology
Resomelagon (AP1189) is a potent, orally active melanocortin receptor (MR) agonist about MC₁ and MC₃. Resomelagon induces ERK1/2 phosphorylation and Ca ²⁺ mobilization. Resomelagon has anti-inflammatory activity. Resomelagon can be used for obesity and chronic inflammation research .

HY-B0288B

Fenoprofen Calcium hydrate 2 Publications Verification LILLY-53858 Calcium hydrate	COX Melanocortin Receptor ERK	Inflammation/Immunology
Fenoprofen (LILLY-53858) Calcium hydrate is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits cyclooxygenase (COX). Fenoprofen Calcium hydrate is a melanocortin receptors (MCRs) positive allosteric modulator (PAM). Fenoprofen Calcium hydrate also increases ERK1/2 activation in HEK293T cells. Fenoprofen Calcium hydrate has anti-arthritic activities and can be used for the study of rheumatoid arthritis and osteoarthritis .

HY-124740

ML00253764	Melanocortin Receptor	Cancer
ML00253764 is a selective melanocortin receptor 4 (MC4R) antagonist, can induce apoptosis by inhibiting ERK1/2 and Akt phosphorylation, and has anticancer activity .

HY-110123

ML-00253764 hydrochloride	Melanocortin Receptor	Neurological Disease Metabolic Disease Cancer
ML-00253764 hydrochloride is a brain penetrant nonpeptidic melanocortin receptor 4 (MC4R) antagonist with a K_i and IC₅₀ of 0.16 μM and 0.103 μM, respectively. ML-00253764 can cross blood-brain barrier .

HY-P1531

γ-1-Melanocyte Stimulating Hormone (MSH), amide	Melanocortin Receptor	Cardiovascular Disease Metabolic Disease Endocrinology
γ-1-Melanocyte Stimulating Hormone (MSH), amide is a 11-amino acid peptide. γ-1-Melanocyte Stimulating Hormone (MSH) regulates sodium (Na ⁺) balance and blood pressure through activation of the melanocortin receptor 3 (MC3-R).

HY-105305

Modimelanotide ABT-719; AP-214	Melanocortin Receptor	Inflammation/Immunology
Modimelanotide (ABT-719) is an α-melanocyte-stimulating hormone analog. Modimelanotide has high specific binding ability to melanocortin receptors (MCR1, 3, 4, 5). Modimelanotide possesses anti-inflammatory and organ-protective effects. Modimelanotide can be used in the research of diseases such as acute kidney injury .

HY-B0288A

Fenoprofen Calcium LILLY-53858 Calcium	COX Melanocortin Receptor ERK	Inflammation/Immunology
Fenoprofen (LILLY-53858) Calcium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits cyclooxygenase (COX). Fenoprofen Calcium is a melanocortin receptors (MCRs) positive allosteric modulator (PAM). Fenoprofen Calcium also increases ERK1/2 activation in HEK293T cells. Fenoprofen Calcium has anti-arthritic activities and can be used for the study of rheumatoid arthritis and osteoarthritis .

HY-N2466A

Melanotan I acetate 1 Publications Verification MT-I acetate; [Nle4,D-Phe7]-α-MSH acetate	Melanocortin Receptor	Cancer
Melanotan I acetate is a potent non-selective melanocortin receptor (MCR) agonist. Melanotan I acetate is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH) that stimulates melanogenesis. Melanotan I acetate can induce skin tanning by mimicking the actions of a-MSH on the melanocortin type 1 receptors (MC1R) of melanocytes. Melanotan I acetate can be used for sunlight-induced skin cancers research .

HY-P991221

ALD1613	Melanocortin Receptor	Metabolic Disease
ALD1613 is a potent neutralizing monoclonal antibody against adrenocorticotropic hormone (ACTH). ALD1613 neutralizes ACTH-induced signaling and inhibits ACTH-induced cyclic AMP accumulation in a mouse adrenal cell line (Y1) via all five melanocortin receptors. ALD1613 significantly reduces plasma corticosterone levels in wild-type rats. ALD1613 can be used in the study of diseases associated with elevated ACTH levels .

HY-P11238

Filimelnotide	Melanocortin Receptor	Endocrinology
Filimelnotide is a agonist of *melanocortin receptor* .

HY-P5971A

TCMCB07 TFA	Melanocortin Receptor	Metabolic Disease
TCMCB07 TFA, a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 TFA plays an important role in cachexia .

HY-P11362

δ-MSH	Melanocortin Receptor	Endocrinology
δ-MSH is a melanocortin peptide. δ-MSH is a weak melanocortin receptor (MCRs) ligand .

HY-P11238A

Filimelnotide acetate	Melanocortin Receptor	Endocrinology
Filimelnotide acetate is a *melanocortin receptor* agonist .

HY-N7587

Chlorophorin	Melanocortin Receptor	Metabolic Disease
Chlorophorin is a inhibitor of *Melanocortin Receptor*. Chlorophorin reduces tyrosinase activity and inhibits a-melanocyte-stimulating hormone-induced melanin production in B16F10 melanoma cells .

HY-168383

(E/Z)-Resomelagon acetate (E/Z)-AP1189 acetate	Melanocortin Receptor	Inflammation/Immunology
(E/Z)-Resomelagon acetate is an agonist of melanocortin receptor 1 (MC1R) and MC3R with anti-inflammatory activities. (E/Z)-Resomelagon can be utilized in inflammation research .

HY-147301B

Resomelagon methanesulfonate AP1189 methanesulfonate	Melanocortin Receptor ERK	Inflammation/Immunology
Resomelagon methanesulfonate (AP1189 methanesulfonate) is the methanesulfonate salt form of Resomelagon (HY-147301). Resomelagon methanesulfonate is an orally active *melanocortin receptor* (MR) agonist. Resomelagon methanesulfonate induces ERK1/2 phosphorylation and Ca ²⁺ mobilization. Resomelagon methanesulfonate exhibits anti-inflammatory activity in mouse peritonitis and peritonitis model. Resomelagon methanesulfonate can be used for obesity and chronic inflammation research .

HY-B1456AR

Fenoprofen (Standard) LILLY-53858 (Standard)	Reference Standards COX Melanocortin Receptor ERK	Inflammation/Immunology
Fenoprofen (Standard) (LILLY-53858 (Standard)) is the analytical standard of Fenoprofen (HY-B1456A). This product is intended for research and analytical applications. Fenoprofenc is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits cyclooxygenase (COX). Fenoprofen is a melanocortin receptors (MCRs) positive allosteric modulator (PAM). Fenoprofen also increases ERK1/2 activation in HEK293T cells. Fenoprofen has anti-arthritic activities and can be used for the study of rheumatoid arthritis and osteoarthritis.

HY-B0288BR

Fenoprofen Calcium hydrate (Standard) LILLY-53858 Calcium hydrate (Standard)	Reference Standards COX Melanocortin Receptor ERK	Inflammation/Immunology
Fenoprofen (LILLY-53858 (Standard)) (Standard) Calcium hydrate is the analytical standard of Fenoprofen Calcium hydrate (HY-B0288B). This product is intended for research and analytical applications. Fenoprofen is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits cyclooxygenase (COX). Fenoprofen is a melanocortin receptors (MCRs) positive allosteric modulator (PAM). Fenoprofen also increases ERK1/2 activation in HEK293T cells. Fenoprofen has anti-arthritic activities and can be used for the study of rheumatoid arthritis and osteoarthritis.

HY-B1456AS

Fenoprofen-13C6 sodium hydrate LILLY-53858-13C6 sodium hydrate	Isotope-Labeled Compounds COX Melanocortin Receptor ERK	Inflammation/Immunology
Fenoprofen- ¹³C₆ (LILLY-53858- ¹³C₆) sodium hydrate is the ¹³C labeled Fenoprofen (HY-B1456A).Fenoprofen (LILLY-53858) is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits cyclooxygenase (COX). Fenoprofen is a melanocortin receptors (MCRs) positive allosteric modulator (PAM). Fenoprofen also increases ERK1/2 activation in HEK293T cells. Fenoprofen has anti-arthritic activities and can be used for the study of rheumatoid arthritis and osteoarthritis .

HY-W559510

MC4R antagonist-3	Melanocortin Receptor	Others
MC4R antagonist-3 (example 130) is a MC4R antagonist with affinity for melanocortin receptors .

HY-P0267A

Melanotan (MT)-II acetate	Melanocortin Receptor	Neurological Disease Metabolic Disease Endocrinology
Melanotan (MT)-II acetate is a *melanocortin receptor* agonist that crosses the blood-brain barrier. Melanotan (MT)-II acetate activates melanocortin receptor 3 and melanocortin receptor 4, and stimulates the release of central endogenous oxytocin. Melanotan (MT)-II acetate reverses recognition memory impairment, increased anxiety levels and reduced exploratory tendency in zebrafish exposed to short-term high-fat diet. Melanotan (MT)-II acetate improves impaired social behavior indicators in mouse models of autism spectrum disorder. Melanotan (MT)-II acetate induces weight loss, reduces food intake and exerts anorectic effects. Melanotan (MT)-II acetate increases intracavernous pressure and erectile activity in brown rats. Melanotan (MT)-II acetate can be used in studies related to memory impairment, anxiety, reduced exploratory behavior, autism spectrum disorder, obesity and erectile dysfunction .

HY-107139R

JNJ-10229570 (Standard)	Reference Standards Melanocortin Receptor	Endocrinology
JNJ-10229570 (Standard) is the analytical standard of JNJ-10229570 (HY-107139). This product is intended for research and analytical applications. JNJ-10229570 is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the production of sebum-specific lipids. JNJ-10229570 inhibits the binding of 125I-NDP-α-MSH to cells expressing human MC1R and MC5R, with IC₅₀ values of 270 nM and 200 nM, respectively.

HY-105305A

Modimelanotide acetate ABT-719 acetate; AP-214 acetate	Melanocortin Receptor	Endocrinology
Modimelanotide (ABT-719) acetate is an α-melanocyte-stimulating hormone analog. Modimelanotide acetate has high specific binding ability to melanocortin receptors (MCR1, 3, 4, 5). Modimelanotide acetate possesses anti-inflammatory and organ-protective effects. Modimelanotide acetate can be used in the research of diseases such as acute kidney injury .

Cat. No.	Product Name	Target	Research Area

HY-P0252

α-MSH Maximum Cited Publications 23 Publications Verification α-Melanocyte-Stimulating Hormone	Melanocortin Receptor	Neurological Disease Metabolic Disease Inflammation/Immunology
α-MSH (α-Melanocyte-Stimulating Hormone), an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH is a post-translational derivative of pro-opiomelanocortin (POMC) .

HY-P1211

Adrenocorticotropic Hormone (ACTH) (1-39), human 1-39-Corticotropin (human)	Melanocortin Receptor	Metabolic Disease
Adrenocorticotropic Hormone (ACTH) (1-39), human is a *melanocortin receptor* agonist.

HY-P0267

Melanotan (MT)-II 1 Publications Verification	Melanocortin Receptor	Neurological Disease
Melanotan (MT)-II, a synthetic *melanocortin* receptor agonist, is an injectable peptide hormone used to promote tanning.

HY-N2466

Melanotan I 1 Publications Verification MT-I; [Nle4,D-Phe7]-α-MSH	Melanocortin Receptor	Neurological Disease Cancer
Melanotan I is a potent non-selective melanocortin receptor (MCR) agonist. Melanotan I is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH) that stimulates melanogenesis. Melanotan I can induce skin tanning by mimicking the actions of a-MSH on the melanocortin type 1 receptors (MC1R) of melanocytes. Melanotan I can be used for the research of sun-induced skin cancer, melanoma, inflammation and male erectile dysfunction .

HY-18678A

Bremelanotide Acetate 1 Publications Verification PT-141 Acetate	Melanocortin Receptor	Metabolic Disease
Bremelanotide (PT-141) Acetate is a *melanocortin receptor* agonist. Bremelanotide Acetate can activate MC4R and increases dopamine release. Bremelanotide Acetate induces appetitive sexual behaviors, female mounting behavior, and repetitive self-grooming. Bremelanotide Acetate can be used for the research of hypoactive sexual desire disorders .

HY-P5971

TCMCB07 Mifomelatide	Melanocortin Receptor	Neurological Disease Metabolic Disease
TCMCB07, a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 plays an important role in cachexia. TCMCB07 has potential transport capabilities .

HY-18678

Bremelanotide 1 Publications Verification PT-141	Melanocortin Receptor	Neurological Disease Metabolic Disease
Bremelanotide (PT-141) is a *melanocortin receptor* agonist. Bremelanotide can activate MC4R and increases dopamine release. Bremelanotide induces appetitive sexual behaviors, female mounting behavior, and repetitive self-grooming. Bremelanotide can be used for the research of hypoactive sexual desire disorders .

HY-P0252A

α-MSH TFA Maximum Cited Publications 23 Publications Verification α-Melanocyte-Stimulating Hormone TFA	Melanocortin Receptor	Neurological Disease Metabolic Disease Inflammation/Immunology
α-MSH (α-Melanocyte-Stimulating Hormone) TFA, an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH TFA is a post-translational derivative of pro-opiomelanocortin (POMC) .

HY-P1531

γ-1-Melanocyte Stimulating Hormone (MSH), amide	Melanocortin Receptor	Cardiovascular Disease Metabolic Disease Endocrinology
γ-1-Melanocyte Stimulating Hormone (MSH), amide is a 11-amino acid peptide. γ-1-Melanocyte Stimulating Hormone (MSH) regulates sodium (Na ⁺) balance and blood pressure through activation of the melanocortin receptor 3 (MC3-R).

HY-105305

Modimelanotide ABT-719; AP-214	Melanocortin Receptor	Inflammation/Immunology
Modimelanotide (ABT-719) is an α-melanocyte-stimulating hormone analog. Modimelanotide has high specific binding ability to melanocortin receptors (MCR1, 3, 4, 5). Modimelanotide possesses anti-inflammatory and organ-protective effects. Modimelanotide can be used in the research of diseases such as acute kidney injury .

HY-N2466A

Melanotan I acetate 1 Publications Verification MT-I acetate; [Nle4,D-Phe7]-α-MSH acetate	Melanocortin Receptor	Cancer
Melanotan I acetate is a potent non-selective melanocortin receptor (MCR) agonist. Melanotan I acetate is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH) that stimulates melanogenesis. Melanotan I acetate can induce skin tanning by mimicking the actions of a-MSH on the melanocortin type 1 receptors (MC1R) of melanocytes. Melanotan I acetate can be used for sunlight-induced skin cancers research .

HY-P11238

Filimelnotide	Melanocortin Receptor	Endocrinology
Filimelnotide is a agonist of *melanocortin receptor* .

HY-P5971A

TCMCB07 TFA	Melanocortin Receptor	Metabolic Disease
TCMCB07 TFA, a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 TFA plays an important role in cachexia .

HY-P11362

δ-MSH	Melanocortin Receptor	Endocrinology
δ-MSH is a melanocortin peptide. δ-MSH is a weak melanocortin receptor (MCRs) ligand .

HY-P11238A

Filimelnotide acetate	Melanocortin Receptor	Endocrinology
Filimelnotide acetate is a *melanocortin receptor* agonist .

HY-P0267A

Melanotan (MT)-II acetate	Melanocortin Receptor	Neurological Disease Metabolic Disease Endocrinology
Melanotan (MT)-II acetate is a *melanocortin receptor* agonist that crosses the blood-brain barrier. Melanotan (MT)-II acetate activates melanocortin receptor 3 and melanocortin receptor 4, and stimulates the release of central endogenous oxytocin. Melanotan (MT)-II acetate reverses recognition memory impairment, increased anxiety levels and reduced exploratory tendency in zebrafish exposed to short-term high-fat diet. Melanotan (MT)-II acetate improves impaired social behavior indicators in mouse models of autism spectrum disorder. Melanotan (MT)-II acetate induces weight loss, reduces food intake and exerts anorectic effects. Melanotan (MT)-II acetate increases intracavernous pressure and erectile activity in brown rats. Melanotan (MT)-II acetate can be used in studies related to memory impairment, anxiety, reduced exploratory behavior, autism spectrum disorder, obesity and erectile dysfunction .

HY-105305A

Modimelanotide acetate ABT-719 acetate; AP-214 acetate	Melanocortin Receptor	Endocrinology
Modimelanotide (ABT-719) acetate is an α-melanocyte-stimulating hormone analog. Modimelanotide acetate has high specific binding ability to melanocortin receptors (MCR1, 3, 4, 5). Modimelanotide acetate possesses anti-inflammatory and organ-protective effects. Modimelanotide acetate can be used in the research of diseases such as acute kidney injury .

Cat. No.	Product Name	Target	Research Area	Image

HY-P991221

ALD1613	Melanocortin Receptor	Metabolic Disease
ALD1613 is a potent neutralizing monoclonal antibody against adrenocorticotropic hormone (ACTH). ALD1613 neutralizes ACTH-induced signaling and inhibits ACTH-induced cyclic AMP accumulation in a mouse adrenal cell line (Y1) via all five melanocortin receptors. ALD1613 significantly reduces plasma corticosterone levels in wild-type rats. ALD1613 can be used in the study of diseases associated with elevated ACTH levels .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7587

Chlorophorin	Artocarpus xanthocarpus Phenols Polyphenols Plants Moraceae Source Classification	Melanocortin Receptor
Chlorophorin is a inhibitor of *Melanocortin Receptor*. Chlorophorin reduces tyrosinase activity and inhibits a-melanocyte-stimulating hormone-induced melanin production in B16F10 melanoma cells .

Species:	Human (2) Mouse (2)
Tag:	His (4) Flag (1)
Source:	HEK293 (1) E. coli Cell-free (2) Sf9 insect cells (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P702372

	MC4R Protein, Mouse (Cell-Free, His) Melanocortin receptor 4; MC4-R	Mouse	E. coli Cell-free
	MC4R is a receptor for adrenocorticotropic hormone and α, β, and γ-MSH and plays a key role in regulating energy homeostasis and somatic cell growth. Mediated by G proteins, it forms disulfide-linked homodimers and higher-order oligomers. MC4R Protein, Mouse (Cell-Free, His) is the recombinant mouse-derived MC4R protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of MC4R Protein, Mouse (Cell-Free, His) is 332 a.a., with molecular weight of 43.0 kDa.

HY-P705900

	MC4R Protein, Human (Cell-Free, His) Melanocortin receptor 4; MC4-R	Human	E. coli Cell-free
	MC4R is a receptor for adrenocorticotropic hormone and α, β, and γ-MSH and plays a key role in regulating energy homeostasis and somatic cell growth. Mediated by G proteins, it forms disulfide-linked homodimers and higher-order oligomers. MC4R Protein, Human (Cell-Free, His) is the recombinant human-derived MC4R protein, expressed by E. coli Cell-free , with C-10*His labeled tag.

HY-P702371

	MC1R-VLPs Protein, Mouse (HEK293, His) Melanocyte-stimulating hormone receptor; Melanocortin receptor 1; MC1-R	Mouse	HEK293
	MC1R-VLPs Protein, Mouse (HEK293, His) is recommended for animal immunization, ELISA. It is not recommended for receptor-ligand interaction detection and SPR/BLI assay since there are other irrelevant membrane proteins of the host on the VLP envelope, and the receptor-ligand interaction will have strong background interference. High requirements for chips and experimental protocols are needed for SPR/BLI assays. If VLP control is required, it is recommended HY-P701236. Tags can only be detected under denaturing conditions.

HY-P703161

	MC4R Protein, Human (sf9, Flag, His) Melanocortin receptor 4; MC4R; Homo sapiens; Human; MC4-R; G-protein coupled receptor; Receptor; Transducer	Human	Sf9 insect cells
	MC4R Protein, Human (sf9, Flag, His) is the recombinant human-derived MC4R, expressed by sf9 insect cells , with His, Flag labeled tag. ,

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HY-B1456AS

Fenoprofen-13C6 sodium hydrate

Fenoprofen- ¹³C₆ (LILLY-53858- ¹³C₆) sodium hydrate is the ¹³C labeled Fenoprofen (HY-B1456A).Fenoprofen (LILLY-53858) is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits cyclooxygenase (COX). Fenoprofen is a melanocortin receptors (MCRs) positive allosteric modulator (PAM). Fenoprofen also increases ERK1/2 activation in HEK293T cells. Fenoprofen has anti-arthritic activities and can be used for the study of rheumatoid arthritis and osteoarthritis .

Host:	Rabbit (2)
Reactivity:	Human (2) Rat (1) Mouse (1)
Application:	IHC-P (2) WB (2)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal (2) Recombinant (2)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P82274

	MC1R Antibody (YA2019) MC1R; MSHR; Melanocyte-stimulating hormone receptor; MSH-R; Melanocortin receptor 1; MC1-R	WB, IHC-P	Human
	MC1R Antibody (YA2019) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MC1R.

HY-P86958

	MC-2 Antibody (YA6651) MC-2 antibody; MC2 antibody; MC5 R antibody; MC5 Receptor antibody; MC5-R antibody; MC5R antibody; MC5R_HUMAN antibody; Melanocortin 5 receptor antibody; Melanocortin receptor 5 antibody;	WB, IHC-P	Human, Mouse, Rat
	MC-2 Antibody (YA6651) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MC-2.

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Melanocortin+Receptor

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