1. Immunology/Inflammation
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  3. Fenoprofen Calcium hydrate

Fenoprofen Calcium hydrate  (Synonyms: Fenoprofen calcium salt dihydrate)

Cat. No.: HY-B0288B Purity: 99.93%
COA Handling Instructions

Fenoprofen Calcium hydrate is a nonsteroidal, anti-inflammatory antiarthritic agent.

For research use only. We do not sell to patients.

Fenoprofen Calcium hydrate Chemical Structure

Fenoprofen Calcium hydrate Chemical Structure

CAS No. : 71720-56-4

Size Price Stock Quantity
Free Sample (0.1 - 0.5 mg)   Apply Now  
10 mM * 1 mL in DMSO USD 61 In-stock
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 61 In-stock
500 mg USD 55 In-stock
1 g USD 79 In-stock
5 g USD 119 In-stock
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Fenoprofen Calcium hydrate is a nonsteroidal, anti-inflammatory antiarthritic agent. Target: Prostaglandin G/H synthase 1 Fenoprofen is a non-steroidal anti-inflammatory, antipyretic, analgesic agent advocated for use in rheumatoid arthritis, degenerative joint disease, ankylosing spondylitis and gout. Fenoprofen has a serum half-life of about 150 to 180 minutes and is at least 99% bound to plasma proteins. It is extensively metabolised after oral administration, the main metabolites being fenoprofen glucuronide and 4-hydroxy-fenoprofen glucuronide [1]. Fenoprofen calcium is revealed for relief of mild to moderate pain in adults and for relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis. In patients with osteoarthritis, the anti-inflammatory and analgesic effects of fenoprofen calcium have been demonstrated by decrease in tenderness as a response to pressure and reduction in night pain, stiffness, swelling, and overall disease activity. These effects have also been demonstrated by attenuation of pain with motion and at rest and increased range of motion in involved joints [2].

IC50 & Target[1]



Molecular Weight









Room temperature in continental US; may vary elsewhere.


4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (358.01 mM)

H2O : 1 mg/mL (3.58 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5801 mL 17.9006 mL 35.8012 mL
5 mM 0.7160 mL 3.5801 mL 7.1602 mL
10 mM 0.3580 mL 1.7901 mL 3.5801 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (8.95 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (8.95 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (8.95 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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