JNJ-10229570 (Standard)
JNJ-10229570 (Standard) is the analytical standard of JNJ-10229570 (HY-107139). This product is intended for research and analytical applications. JNJ-10229570 is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the production of sebum-specific lipids. JNJ-10229570 inhibits the binding of 125I-NDP-α-MSH to cells expressing human MC1R and MC5R, with IC50 values of 270 nM and 200 nM, respectively.
For research use only. We do not sell to patients.
- CAS No.: 524923-88-4
- Formula: C22H19N3O2S
- Molecular Weight:389.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 270 nM (human MC1R), 200 nM (human MC5R)[1].
Chemical Information
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CAS No. 524923-88-4
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Molecular Weight 389.47
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Formula C22H19N3O2S
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SMILES
COC1=C(C=CC=C1)C(N(C2=C(C=CC=C2)OC)S/3)=NC3=N\C4=CC=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
JNJ-10229570 (Standard) Related Classifications
HY-107139R Related Classifications
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