2. GPCR/G Protein Neuronal Signaling
  3. Melanocortin Receptor
  4. γ-1-Melanocyte Stimulating Hormone (MSH), amide

γ-1-Melanocyte Stimulating Hormone (MSH), amide 

Cat. No.: HY-P1531 Purity: 99.32%
COA Handling Instructions

γ-1-Melanocyte Stimulating Hormone (MSH), amide is a 11-amino acid peptide. γ-1-Melanocyte Stimulating Hormone (MSH) regulates sodium (Na+) balance and blood pressure through activation of the melanocortin receptor 3 (MC3-R).

For research use only. We do not sell to patients.

Custom Peptide Synthesis

γ-1-Melanocyte Stimulating Hormone (MSH), amide Chemical Structure

γ-1-Melanocyte Stimulating Hormone (MSH), amide Chemical Structure

Size Price Stock Quantity
1 mg USD 90 In-stock
5 mg USD 290 In-stock
10 mg USD 490 In-stock
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100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

γ-1-Melanocyte Stimulating Hormone (MSH), amide Related Antibodies

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Description

γ-1-Melanocyte Stimulating Hormone (MSH), amide is a 11-amino acid peptide. γ-1-Melanocyte Stimulating Hormone (MSH) regulates sodium (Na+) balance and blood pressure through activation of the melanocortin receptor 3 (MC3-R).

IC50 & Target

Melanocortin receptor 3 (MC3-R)[1]
In Vitro

γ-Melanocyte Stimulating Hormone (γ-MSH) regulates a multitude of metabolic functions including energy homeostasis, food intake, sodium (Na+) balance, and blood pressure regulation. γ-MSH is processed from the precursor hormone pro-opio-melanocortin (POMC) in the pituitary gland, where component peptides are released into the cerebral spinal fluid and systemic circulation. The natural receptor for γ-MSH is the melanocortin receptor 3 (MC3-R), a G-protein-coupled receptor that activates adenylate cyclase and is expressed in brain (hypothalamus, cortex, and thalamus), gut, placenta, and kidney. γ-MSH regulates Na+ balance by inducing urinary Na+ excretion (natriuresis) under conditions of high dietary salt intake[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

γ-1-Melanocyte Stimulating Hormone (MSH), amide Related Antibodies
Molecular Weight

1512.90

Appearance

Solid

Formula

C72H97N21O14S
Sequence Shortening

YVMGHFRWDRF-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 25 mg/mL (16.52 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6610 mL 3.3049 mL 6.6098 mL
5 mM 0.1322 mL 0.6610 mL 1.3220 mL
10 mM 0.0661 mL 0.3305 mL 0.6610 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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γ-1-Melanocyte Stimulating Hormone (MSH), amide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Keywords:

γ-1-Melanocyte Stimulating Hormone (MSH), amideMelanocortin ReceptorMC ReceptorInhibitorinhibitorinhibit

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