γ-1-Melanocyte Stimulating Hormone (MSH), amide

Name: γ-1-Melanocyte Stimulating Hormone (MSH), amide
Brand: MedChemExpress
SKU: HY-P1531
Rating: 4.5 (1 reviews)

製品番号: HY-P1531 純度: 97.03%: Data Sheet SDS COA 取扱説明書
FAQs
Technical Support

γ-1-Melanocyte Stimulating Hormone (MSH), amide is a 11-amino acid peptide. γ-1-Melanocyte Stimulating Hormone (MSH) regulates sodium (Na⁺) balance and blood pressure through activation of the melanocortin receptor 3 (MC3-R).

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カスタムペプチド

γ-1-Melanocyte Stimulating Hormone (MSH), amide 構造式

CAS 番号 : 72629-65-3

容量	価格（税別）	在庫状況	数量
1 mg	$90	在庫あり	Estimated Time of Arrival: December 31
5 mg	$290	在庫あり	Estimated Time of Arrival: December 31
10 mg	$490	在庫あり	Estimated Time of Arrival: December 31
50 mg		お問い合わせ
100 mg		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 1 publication(s) in Google Scholar

Melanocortin Receptor アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

MC1R MC3R MC2R MC4R MC5R

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

IC₅₀ & Target

MC3R

体外実験

γ-Melanocyte Stimulating Hormone (γ-MSH) regulates a multitude of metabolic functions including energy homeostasis, food intake, sodium (Na⁺) balance, and blood pressure regulation. γ-MSH is processed from the precursor hormone pro-opio-melanocortin (POMC) in the pituitary gland, where component peptides are released into the cerebral spinal fluid and systemic circulation. The natural receptor for γ-MSH is the melanocortin receptor 3 (MC3-R), a G-protein-coupled receptor that activates adenylate cyclase and is expressed in brain (hypothalamus, cortex, and thalamus), gut, placenta, and kidney. γ-MSH regulates Na⁺ balance by inducing urinary Na⁺ excretion (natriuresis) under conditions of high dietary salt intake^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1512.90

分子式

C₇₂H₉₇N₂₁O₁₄S

CAS 番号

72629-65-3

Appearance

Solid

Color

White to light yellow

Sequence Shortening

YVMGHFRWDRF-NH2

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

polypeptide, sealed storage, away from moisture and light, under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (polypeptide, sealed storage, away from moisture and light, under nitrogen)

溶剤 & 溶解度

体外:

H₂O : 25 mg/mL (16.52 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.6610 mL	3.3049 mL	6.6098 mL
5 mM	0.1322 mL	0.6610 mL	1.3220 mL
10 mM	0.0661 mL	0.3305 mL	0.6610 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

純度とドキュメンテーション

純度: 97.03%

Select Batch:

データシート (270 KB) SDS (252 KB)

COA (243 KB) RP-HPLC (258 KB) MS (70 KB) Elemental Analysis Report (102 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Kathpalia PP, et al. The natriuretic mechanism of Gamma-Melanocyte-Stimulating Hormone. Peptides. 2011 May;32(5):1068-72. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	0.6610 mL	3.3049 mL	6.6098 mL	16.5246 mL
	5 mM	0.1322 mL	0.6610 mL	1.3220 mL	3.3049 mL
	10 mM	0.0661 mL	0.3305 mL	0.6610 mL	1.6525 mL
	15 mM	0.0441 mL	0.2203 mL	0.4407 mL	1.1016 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.