34 Results for "

gene carrier

" in MedChemExpress (MCE) Product Catalog:
Products (34)

34 Results for "gene carrier" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-W583868
CAS No.: 26662-94-2
Synonyms: 1,2-POPE; 16:0-18:1 PE
Target:  

Liposome

Research Areas:  

Others

1-Palmitoyl-2-oleoyl-sn-glycero-3-PE (1,2-POPE; 16:0-18:1 PE) is a phosphatidylethanolamine (PE) lipid. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can induce lipid bilayer to form a hexagonal phase (HII) structure in an acidic environment and promote membrane fusion. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can enhance the endosomal escape ability of lipid nanoparticles (LNPs) and improve the cellular delivery efficiency of nucleic acid drugs such as mRNA. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can be used for LNP carrier targeting of gene therapy and mRNA vaccines .
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1
1 Cited Publications
Cat. No.: HY-112760
CAS No.: 247925-28-6
Purity:  ≥98.0%
Synonyms: DSPE-mPEG2000 sodium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] sodium
Target:  

Liposome

Research Areas:  

Others

18:0 mPEG2000 PE (DSPE-mPEG2000) sodium is a conjugate of phospholipid and polyethylene glycol, and it can serve as an important PEG lipid component in lipid nanoparticles (LNPs). 18:0 mPEG2000 PE sodium can be used in the research of gene transfection, drug carriers and drug delivery .
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1
1 Cited Publications
Cat. No.: HY-128854
CAS No.: 792-74-5
Purity:  ≥98.0%
Dimethyl biphenyl-4,4'-dicarboxylate (Biphenyl dimethyl dicarboxylate) is a hepatoprotective agent. Dimethyl biphenyl-4,4'-dicarboxylate stimulates the Jak/Stat signaling pathway and induces the expression of IFN-α-stimulated genes, particularly 6-16 and ISG12. Dimethyl biphenyl-4,4'-dicarboxylate inhibits the replication of pregenomic RNA and HBeAg. Polymer micelles loaded with Dimethyl biphenyl-4,4'-dicarboxylate can serve as carriers for the compound. Dimethyl biphenyl-4,4'-dicarboxylate can be used as an auxiliary improving agent for chronic hepatitis. Dimethyl biphenyl-4,4'-dicarboxylate is applicable to research related to chronic hepatitis B .
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Cat. No.: HY-155882
CAS No.: 80506-64-5
Synonyms: mPEG750-NH2
mPEG750-amine (mPEG750-NH2) is a chemical modification reagent for nanoparticles, capable of covalently binding to Ad-PVA to form Ad-PVA-PEG polymers. mPEG750-amine stabilizes gene delivery complexes by providing steric hindrance, reducing particle aggregation, while enhancing the water solubility and serum stability of the complex, reducing carrier cytotoxicity, and assisting in the efficient condensation of pDNA by cationic components to form nanoparticles that can be endocytosed by cells. mPEG750-amine can also be used to synthesize folate-conjugated polymer micelles for encapsulating the anticancer agent Camptothecin (HY-16560). Folate-conjugated polymer micelles are effective carriers for poorly soluble anticancer drugs, capable of avoiding macrophages and acting through folate receptor (FR)-mediated endocytosis to target tumor cells. mPEG750-amine can be applied to research in the field of non-viral gene delivery, as a component of gene delivery vectors, facilitating the safe and efficient delivery of nucleic acid drugs to target cells .
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Cat. No.: HY-113355
CAS No.: 58-68-4
NADH is an orally active dehydrogenase coenzyme that acts as a crucial electron carrier in cellular respiration and participates in ATP production. NADH promotes metabolism, supports brain function, and counteracts oxidative stress by transferring electrons to the electron transport chain. As a signaling molecule, NADH regulates multiple biological processes, including anti-apoptosis, synaptic plasticity, gene expression, and calcium homeostasis. Redox imbalance of NADH/NAD⁺ is one of the key pathological mechanisms of various diseases, such as diabetic nephropathy, neurodegenerative diseases, and ischemia-reperfusion injury.
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Cat. No.: HY-112624U
CAS No.: 9004-54-0
Synonyms: Dextran 20; Dextran D20; Dextran T20(MW 16000-24000)
Dextran T20 (Dextran 20; Dextran D20) (MW 20,000) is a dehydrated glucose polymer with an average molecular weight of 20,000. Dextran T20 (MW 20,000) has excellent biodegradability and good biocompatibility, and can be used as a gene delivery vector, an immune adjuvant carrier, and a hemoglobin stabilizer .
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Cat. No.: HY-159069
CAS No.: 9010-72-4
Purity:  95.02%
Zymosan (ZM), 95% is a yeast cell wall-derived carbohydrate-rich preparation and immunomodulator. Zymosan (ZM), 95% binds to and activates TLR-2, TLR-4, and Dectin-1 receptor to trigger downstream signaling pathways. Zymosan (ZM), 95% upregulates TLR-2, TLR-4, and TNF-α mRNA expression, increases serum TNF-α levels, and stimulates splenocyte number and viability in mice. Zymosan (ZM), 95% attenuates melanoma growth progression, modulates macrophage marker gene expression, and mediates phagocytosis, ROS generation, and cytokine production. Zymosan (ZM), 95% reduces Connexin 43 protein and mRNA levels, inhibits gap junctional intercellular communication, and induces proinflammatory factor production in human corneal cells. Zymosan (ZM), 95% induces peritoneal inflammation in mice, functions as a drug carrier, and supports fibroblast cell attachment in hydrogel formulations. Zymosan (ZM), 95% can be used for the research of melanoma, tumors, fungal keratitis, ocular surface inflammatory disorders, and peritoneal inflammation .
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Cat. No.: HY-P3436
CAS No.: 771479-86-8
Target:  

Exosomes

Research Areas:  

Cardiovascular Disease

WLSEAGPVVTVRALRGTGSW is a cardiomyocyte-targeting peptide that specifically recognizes tenascin X on the surface of cardiomyocytes. WLSEAGPVVTVRALRGTGSW can serve as a targeting ligand to conjugate with various therapeutic carriers (drugs, genes, exosomes, nanoparticles, etc.) for research on cardiovascular diseases (such as myocardial infarction, heart failure) .
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Cat. No.: HY-137499
CAS No.: 2739805-63-9
Purity:  ≥95.0%
Research Areas:  

Neurological Disease

NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination .
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Cat. No.: HY-W322225
CAS No.: 59752-57-7
Synonyms: DLPE; 1,2-Dilauroyl-sn-glycero-3-PE
Target:  

Liposome

Research Areas:  

Others

1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine (DLPE; 1,2-Dilauroyl-sn-glycero-3-PE) is an anionic phospholipid. 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine promotes the endocytosis of liposome-DNA complexes into target cells, and subsequently mediates membrane fusion between liposome carriers and endosomes to deliver DNA into the nucleus. 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine is a component of anionic artificial viral envelope liposomes, which deliver plasmid DNA to hepatoma cells without serum inhibition. 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine enables the construction of biocompatible non-viral gene delivery vector systems. 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine is applicable for liposome synthesis .
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Cat. No.: HY-N11882
CAS No.: 4299-57-4
Synonyms: PQ-9
Plastoquinone (PQ-9) is a photosynthetic electron carrier as well as a redox sensor capable of regulating state transitions and gene expression. Plastoquinone transfers electrons to the cytochrome b6/f complex via the Q cycle, and participates in the establishment of the thylakoid transmembrane pH gradient. Plastoquinone can react with ROS. Plastoquinone is used in plant photosynthesis research .
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Cat. No.: HY-17659
CAS No.: 112055-76-2
Target:  

Drug Derivative

Research Areas:  

Others

Decylplastoquinone is lipid-soluble derivative of plastoquinone (HY-N11882). Plastoquinone (PQ-9), a potent electron carrier, is an essential component of photosynthesis. Plastoquinone is also a redox sensor that regulates state transitions and gene expression .
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Cat. No.: HY-P3436A
Target:  

Exosomes

Research Areas:  

Cardiovascular Disease

WLSEAGPVVTVRALRGTGSW TFA is a cardiomyocyte-targeting peptide that specifically recognizes tenascin X on the surface of cardiomyocytes. WLSEAGPVVTVRALRGTGSW TFA can serve as a targeting ligand to conjugate with various therapeutic carriers (drugs, genes, exosomes, nanoparticles, etc.) for research on cardiovascular diseases (such as myocardial infarction, heart failure) .
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Cat. No.: HY-128854R
CAS No.: 792-74-5
Dimethyl biphenyl-4,4'-dicarboxylate (Standard) is the analytical standard of Dimethyl biphenyl-4,4'-dicarboxylate (HY-128854). This product is intended for research and analytical applications. Dimethyl biphenyl-4,4'-dicarboxylate (Biphenyl dimethyl dicarboxylate) is a hepatoprotective agent. Dimethyl biphenyl-4,4'-dicarboxylate stimulates the Jak/Stat signaling pathway and induces the expression of IFN-α-stimulated genes, particularly 6-16 and ISG12. Dimethyl biphenyl-4,4'-dicarboxylate inhibits the replication of pregenomic RNA and HBeAg. Polymer micelles loaded with Dimethyl biphenyl-4,4'-dicarboxylate can serve as carriers for the compound. Dimethyl biphenyl-4,4'-dicarboxylate can be used as an auxiliary improving agent for chronic hepatitis. Dimethyl biphenyl-4,4'-dicarboxylate is applicable to research related to chronic hepatitis B .
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Cat. No.: HY-128854S
CAS No.: 1219803-50-5
Dimethyl biphenyl-4,4'-dicarboxylate-d8 is the d8-labeled Dimethyl biphenyl-4,4'-dicarboxylate (HY-128854). Dimethyl biphenyl-4,4'-dicarboxylate (Biphenyl dimethyl dicarboxylate) is a hepatoprotective agent. Dimethyl biphenyl-4,4'-dicarboxylate stimulates the Jak/Stat signaling pathway and induces the expression of IFN-α-stimulated genes, particularly 6-16 and ISG12. Dimethyl biphenyl-4,4'-dicarboxylate inhibits the replication of pregenomic RNA and HBeAg. Polymer micelles loaded with Dimethyl biphenyl-4,4'-dicarboxylate can serve as carriers for the compound. Dimethyl biphenyl-4,4'-dicarboxylate can be used as an auxiliary improving agent for chronic hepatitis. Dimethyl biphenyl-4,4'-dicarboxylate is applicable to research related to chronic hepatitis B .
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Cat. No.: HY-P703199
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SLC2A1; HepG2 Glucose Transporter; Prev. GLUT1; Dystonia gene 9; Prev. HTLVR; Solute carrier Family 2, Facilitated Glucose Transporter Member 5; Prev. GLUT; Solute carrier Family 2 Facilitated Glucose Transporter Member 1; Prev. CSE; Glucose Transporter T
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P703198
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SLC2A1; HepG2 Glucose Transporter; Prev. GLUT1; Dystonia gene 9; Prev. HTLVR; Solute carrier Family 2, Facilitated Glucose Transporter Member 5; Prev. GLUT; Solute carrier Family 2 Facilitated Glucose Transporter Member 1; Prev. CSE; Glucose Transporter T
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P703197
Synonyms: SLC2A1; HepG2 Glucose Transporter; Prev. GLUT1; Dystonia gene 9; Prev. HTLVR; Solute carrier Family 2, Facilitated Glucose Transporter Member 5; Prev. GLUT; Solute carrier Family 2 Facilitated Glucose Transporter Member 1; Prev. CSE; Glucose Transporter T
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P810945
Synonyms: HKE4, RING5, SLC39A7, Zinc transporter SLC39A7, Histidine-rich membrane protein Ke4, Really interesting new gene 5 protein, Solute carrier family 39 member 7, ZIP7

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P811318
Synonyms: NTCP, GIG29, SLC10A1, Hepatic sodium/bile acid cotransporter, Cell growth-inhibiting gene 29 protein, Na(+)/bile acid cotransporter, Na(+)/taurocholate transport protein, Sodium/taurocholate cotransporting polypeptide, Solute carrier family 10 member 1

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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