WLSEAGPVVTVRALRGTGSW
Based on 1 Customer Validation
WLSEAGPVVTVRALRGTGSW is a cardiomyocyte-targeting peptide that specifically recognizes tenascin X on the surface of cardiomyocytes. WLSEAGPVVTVRALRGTGSW can serve as a targeting ligand to conjugate with various therapeutic carriers (drugs, genes, exosomes, nanoparticles, etc.) for research on cardiovascular diseases (such as myocardial infarction, heart failure).
For research use only. We do not sell to patients.
- Purity: 99.91%
- CAS No.: 771479-86-8
- Formula: C97H152N28O27
- Molecular Weight:2142.42
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
WLSEAGPVVTVRALRGTGSW enhances the internalization of exosomes by cardiomyocytes and promotes the targeted delivery of miR302 after conjugation with bone marrow mesenchymal stem cell-derived exosomes[1].
WLSEAGPVVTVRALRGTGSW mediates the preferential localization of phages displaying this peptide in mouse heart tissues, including uptake by cardiomyocytes in vivo, and blocks the uptake of phages displaying its own sequence by primary cardiomyocytes[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 771479-86-8
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Appearance Solid
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Molecular Weight 2142.42
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Formula C97H152N28O27
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Color White to off-white
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Sequence Shortening
WLSEAGPVVTVRALRGTGSW
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (258 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1].
Gu J, et al. Engineered bone marrow mesenchymal stem cell-derived exosomes loaded with miR302 through the cardiomyocyte specific peptide can reduce myocardial ischemia and reperfusion (I/R) injury. Journal of translational medicine. 2024 Feb 17;22(1):168.
[Content Brief]
[2]. McGuire MJ, et al. In vitro selection of a peptide with high selectivity for cardiomyocytes in vivo. J Mol Biol. 2004;342(1):171-182. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
WLSEAGPVVTVRALRGTGSW Related Classifications
HY-P3436 Related Classifications
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