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  3. WLSEAGPVVTVRALRGTGSW

WLSEAGPVVTVRALRGTGSW is a cardiomyocyte-targeting peptide that specifically recognizes tenascin X on the surface of cardiomyocytes. WLSEAGPVVTVRALRGTGSW can serve as a targeting ligand to conjugate with various therapeutic carriers (drugs, genes, exosomes, nanoparticles, etc.) for research on cardiovascular diseases (such as myocardial infarction, heart failure).

For research use only. We do not sell to patients.

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WLSEAGPVVTVRALRGTGSW

WLSEAGPVVTVRALRGTGSW Chemical Structure

CAS No. : 771479-86-8

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Based on 1 publication(s) in Google Scholar

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Description

WLSEAGPVVTVRALRGTGSW is a cardiomyocyte-targeting peptide that specifically recognizes tenascin X on the surface of cardiomyocytes. WLSEAGPVVTVRALRGTGSW can serve as a targeting ligand to conjugate with various therapeutic carriers (drugs, genes, exosomes, nanoparticles, etc.) for research on cardiovascular diseases (such as myocardial infarction, heart failure)[1][2].

In Vitro

WLSEAGPVVTVRALRGTGSW enhances the internalization of exosomes by cardiomyocytes and promotes the targeted delivery of miR302 after conjugation with bone marrow mesenchymal stem cell-derived exosomes[1].
WLSEAGPVVTVRALRGTGSW mediates the preferential localization of phages displaying this peptide in mouse heart tissues, including uptake by cardiomyocytes in vivo, and blocks the uptake of phages displaying its own sequence by primary cardiomyocytes[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

2142.42

Formula

C97H152N28O27

CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

WLSEAGPVVTVRALRGTGSW

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
WLSEAGPVVTVRALRGTGSW
Cat. No.:
HY-P3436
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