SLC37A4 Protein, Human (sf9, His, MBP, FLAG)
SLC37A4 protein, an endoplasmic reticulum antiporter, transports glucose-6-phosphate into the endoplasmic reticulum lumen while moving inorganic phosphate in the opposite direction. This function is integral to glucose production through glycogenolysis and gluconeogenesis, underscoring SLC37A4's central role in regulating blood glucose levels and maintaining metabolic balance. SLC37A4 Protein, Human (sf9, His, MBP, FLAG) is the recombinant human-derived SLC37A4 protein, expressed by sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag.
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
SLC37A4 protein, an endoplasmic reticulum antiporter, transports glucose-6-phosphate into the endoplasmic reticulum lumen while moving inorganic phosphate in the opposite direction. This function is integral to glucose production through glycogenolysis and gluconeogenesis, underscoring SLC37A4's central role in regulating blood glucose levels and maintaining metabolic balance. SLC37A4 Protein, Human (sf9, His, MBP, FLAG) is the recombinant human-derived SLC37A4 protein, expressed by sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag.
Background
SLC37A4 protein serves as an inorganic phosphate and glucose-6-phosphate antiporter located in the endoplasmic reticulum. Its primary function involves the transport of cytoplasmic glucose-6-phosphate into the endoplasmic reticulum lumen, while simultaneously translocating inorganic phosphate in the opposite direction. This activity, documented in recent research, contributes to the complex responsible for glucose production through glycogenolysis and gluconeogenesis. As a crucial participant in these metabolic pathways, SLC37A4 plays a central role in the homeostatic regulation of blood glucose levels, highlighting its significance in maintaining metabolic balance.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag N-MBP;C-Flag;N-8*His
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Accession
O43826 (A2-E429)
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Gene ID2542
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Molecular Construction
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N-term
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8*His-MBP
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SLC37A4 (A2-E429)
Accession # O43826 -
Flag
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C-term
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Protein Length
Full Length
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Synonyms
SLC37A4; Sugar-Phosphate Exchange Protein 4; Prev. G6PT1; Glucose-6-Phosphate Translocase; Prev. G6PT3; Glucose-5-Phosphate Transporter; Prev. G6PT2; TRG-19; G6PT; Glucose-6-Phosphatase, Transport (Phosphate/Pyrophosphate) Protein 2; Glucose-6-Phosphate E
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AA Sequence
AAQGYGYYRTVIFSAMFGGYSLYYFNRKTFSFVMPSLVEEIPLDKDDLGFITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNIFFAWSSTVPVFAALWFLNGLAQGLGWPPCGKVLRKWFEPSQFGTWWAILSTSMNLAGGLGPILATILAQSYSWRSTLALSGALCVVVSFLCLLLIHNEPADVGLRNLDPMPSEGKKGSLKEESTLQELLLSPYLWVLSTGYLVVFGVKTCCTDWGQFFLIQEKGQSALVGSSYMSALEVGGLVGSIAAGYLSDRAMAKAGLSNYGNPRHGLLLFMMAGMTVSMYLFRVTVTSDSPKLWILVLGAVFGFSSYGPIALFGVIANESAPPNLCGTSHAIVGLMANVGGFLAGLPFSTIAKHYSWSTAFWVAEVICAASTAAFFLLRNIRTKMGRVSKKAE
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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