Search Result
Results for "
growth promoter
" in MedChemExpress (MCE) Product Catalog:
3
Biochemical Assay Reagents
4
Isotope-Labeled Compounds
| Cat. No. |
상품명 |
Target |
연구분야 |
Chemical Structure |
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- HY-A0122
-
-
-
- HY-N2593
-
|
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Carnitine Palmitoyltransferase (CPT)
Reactive Oxygen Species (ROS)
Autophagy
Apoptosis
NF-κB
PI3K
Akt
MMP
Keap1-Nrf2
|
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Isorhapontigenin is an orally active dietary polyphenol. Isorhapontigenin acts as a potent antioxidant that reduces the production of reactive oxygen species (ROS). Isorhapontigenin promotes the binding of JUN to the AP-1 site on the SESN2 promoter, induces SESN2 transcription, triggers MAPK8-dependent JUN activation, and upregulates the expression of PPAR-α, PGC-1α and CPT-1A to facilitate fatty acid oxidation. Isorhapontigenin induces autophagy, apoptosis and preadipocyte differentiation; it inhibits tumor growth, cell invasion, NF-κB transcriptional activity, the PI3K/Akt signaling pathway, STAT1 phosphorylation and MMP-2 expression. Isorhapontigenin alleviates oxidative stress, inflammatory cytokine release and triglyceride accumulation; it increases intracellular ATP levels and promotes Nrf2 nuclear translocation. Isorhapontigenin improves insulin sensitivity in adipose tissue and glucose tolerance, and reduces postprandial blood glucose, insulin and free fatty acid levels. Isorhapontigenin is applicable to research on bladder cancer, liver injury, chronic obstructive pulmonary disease, acute lung injury and type 2 diabetes .
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- HY-150190
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F5446
1 Publications Verification
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Histone Methyltransferase
Apoptosis
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Cancer
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F5446 (Compound 1) is a selective small molecule inhibitor of SUV39H1 methyltransferase. F5446 decreases H3K9me3 deposition at the FAS promoter, increases Fas expression and increases colorectal carcinoma cell sensitivity to FasL-induced apoptosis in vitro. F5446 suppresses human colon tumor xenograft growth in vivo .
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- HY-W116336D
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Biochemical Assay Reagents
Fungal
Bacterial
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Infection
Cancer
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Zinc oxide, <100 nm particle size is a nitrate reductase modulator and growth promoter with plant stress resistance activity and oral toxicity. Zinc oxide, <100 nm particle size acts as a nutrient source for maize plants. By enhancing nitrate reductase activity and reducing free proline levels, it significantly improves plant height, root length and dry matter weight of maize, and its growth-promoting effect is comparable to that of traditional zinc sulfate fertilizer. Zinc oxide, <100 nm particle size induces anemia-related and persistent tissue inflammatory damage, leading to obvious histopathological adverse reactions in the stomach, pancreas, eyes and prostate of rats. Zinc oxide, <100 nm particle size acts as a non-toxic antibacterial agent and selective cytotoxin against multiple bacteria, fungi and spores .
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- HY-122485
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Bacterial
|
Infection
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α-Copaene is a potent attractant for male Mediterranean fruit flies Ceratitis capitata.α-Copaene can be found as a minor component in the essential oils of various plant species. α-Copaene can inhibit bacterial growth with a minimum inhibitory concentration of 0.5-1 μL/mL. α-Copaene suppresses biofilm formation by decreasing the hydrophobicity of the cell surface. α-Copaene can be used as an oviposition promoter of Bactrocera oleae .
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- HY-150287A
-
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ITS-X
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Biochemical Assay Reagents
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Others
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Insulin-Transferrin-Selenium-Ethanolamine (ITS-X) is a cell culture supplement as well as a cell growth and adhesion promoter. Insulin-Transferrin-Selenium-Ethanolamine supports adhesion, pseudopodium formation, pseudopodium elongation and proliferation of adherent cancer cells in serum-free culture systems .
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- HY-137129
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Dihydrofolate reductase (DHFR)
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Cancer
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10-Formyl-7,8-dihydrofolic acid is a biologically active folic acid and growth promoter. 10-Formyl-7,8-dihydrofolic acid serves as a substrate for aminoimidazolecarboxamide ribonucleotide transformylase and dihydrofolate reductase (DHFR) to support catalytic reactions (with detection wavelengths of 552 nm and 340 nm, respectively). 10-Formyl-7,8-dihydrofolic acid not only promotes the growth of leukemia cells, but also effectively reverses the growth inhibition induced by antifolate drugs under folate-deficient conditions. 10-Formyl-7,8-dihydrofolic acid can be used in the research of leukemia .
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- HY-N6709
-
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α-Zearalanol
|
Estrogen Receptor/ERR
|
Endocrinology
|
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Zeranol, a metabolite of the mycoestrogen zearalenone, is an estrogen receptor agonist. Zeranol is used as a growth promoter of livestock due to its strong estrogenic activity .
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- HY-129751
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Difurazon hydrochloride
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Bacterial
TrxR
Apoptosis
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Infection
Cancer
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Nitrovin hydrochloride is an antibacterial growth promoter. Nitrovin hydrochloride induces ROS-mediated non-apoptotic and apoptotic-like cell death by targeting TrxR1. Nitrovin hydrochloride has anticancer activity, with IC50 values of 1.31-6.60 μM for tumor and normal cells .
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- HY-N10341
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IFNAR
ROCK
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Inflammation/Immunology
Cancer
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Centaureidin is an orally active IFN-promoter that can be isolated from Bidens pilosa with an EC50 of 0.9 μg/mL. Centaureidin activates the Rho signal pathway, leading to actin and tubulin disassembly, and resulting in dendrite retraction and stress fiber formation in melanocytes. Centaureidin shows high tumor cell growth inhibitory activities. Centaureidin significantly inhibits paw edema in mice [1][2][3][4][5].
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- HY-W777284
-
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Isotope-Labeled Compounds
Estrogen Receptor/ERR
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Endocrinology
|
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Zeranol-d5 (mixture of diastereomers) is the deuterium labeled Zeranol (HY-N6709). Zeranol, a metabolite of the mycoestrogen zearalenone, is an estrogen receptor agonist. Zeranol is used as a growth promoter of livestock due to its strong estrogenic activity .
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- HY-117406
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-
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- HY-N6709R
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-
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- HY-W504391
-
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Difurazon
|
Bacterial
TrxR
Apoptosis
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Infection
Cancer
|
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Nitrovin is an antibacterial growth promoter. Nitrovin induces ROS-mediated non-apoptotic and apoptotic-like cell death by targeting TrxR1. Nitrovin has anticancer activity, with IC50 values of 1.31-6.60 μM for tumor and normal cells .
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- HY-117406R
-
|
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Adrenergic Receptor
Reference Standards
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Metabolic Disease
|
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Clencyclohexerol (Standard) is the analytical standard of Clencyclohexerol (HY-117406). This product is intended for research and analytical applications. Clencyclohexerol is a β2 adrenergic receptor agonist. Clencyclohexerol can be used as a growth promoter in animals .
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- HY-120519
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-
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- HY-N14742
-
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Others
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Others
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Pteridic acid A is a plant growth promoter. Pteridic acid A has Auxin-like plant growth hormone activity, and 1 nM can promote the growth of legumes and other plant roots .
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- HY-177375
-
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MDM-2/p53
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Cancer
|
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dsP53-285 saRNA is a small activating RNA (saRNA) that readily activates wild-type p53 expression by targeting its promoter. dsP53-285 saRNA suppresses bladder cancer cells growth and metastasis .
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- HY-162796
-
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Apoptosis
G-quadruplex
c-Myc
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Cancer
|
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TS-2 is a fluorescent ligand of c-Myc G4 with anticancer activity. TS-2 inhibits the growth of cancer cells and induces apoptosis of cancer cells by targeting the c-MYC oncogene promoter G4, causing transcriptional repression of the c-Myc oncogene .
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- HY-N15532
-
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Trk Receptor
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Neurological Disease
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Phenylmethyl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside (Compound 12) is a nerve growth factor (NGF) secretion promoter, which is found in plants of the genus Piper. Phenylmethyl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside is promising for research of neurodegenerative diseases (such as Parkinson's disease and Alzheimer's disease) and diabetic polyneuropathy .
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- HY-149875
-
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Bacterial
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Infection
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T3SS-IN-1 (compound B9) is a potent inhibitor of type III secretion system (T3SS) inhibitor. T3SS-IN-1 can also inhibits hpa1 promoter activity and harpin protein expression without affecting bacterial growth .
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-
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- HY-162688
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Telomerase
G-quadruplex
Apoptosis
Ferroptosis
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Others
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Anticancer agent 239 (Compound 5) is a ligand of hTERT promoter G-quadruplex DNA structures (hTERT G4) (Kd = 1.1 μM), and downregulates hTERT expression. Anticancer agent 239 decreases telomerase activity, shortens telomere length, and induces DNA damage, acute cellular senescence, and apoptosis. Anticancer agent 239 causes mitochondrial dysfunction, disrupts iron metabolism and activates ferroptosis in cancer cells. Anticancer agent 239 inhibits tumor growth in MDA-MB-231 xenograft mouse model .
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-
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- HY-P99911
-
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MEDI-6383
|
Orexin Receptor (OX Receptor)
|
Inflammation/Immunology
Cancer
|
|
Efizonerimod alfa (MEDI-6383) is a recombinant human OX40L IgG4P Fc fusion protein that assembles into a hexameric structure and exerts potent agonist activity upon binding to OX40. The activity of Efizonerimod alfa is enhanced by Fcγ receptor-mediated aggregation. Efizonerimod alfa binds to OX40 on the surface of activated T cells, induces NF-κB promoter activity in OX40-expressing T cells, and triggers the production of Th1-type cytokines, T cell proliferation, and resistance to regulatory T cell (Treg)-mediated suppression. Efizonerimod alfa enhances the cytolytic activity of tumor-reactive T cells and slows tumor growth in immunodeficient mice. Efizonerimod alfa induces the proliferation of CD4, CD8, and B cells in the peripheral blood of healthy non-human primates. Efizonerimod alfa can be used in the research of advanced solid malignancies and melanoma .
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- HY-W742012
-
|
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Isotope-Labeled Compounds
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Others
|
|
Clencyclohexerol-d10 is the deuterium-labeled Clencyclohexerol (HY-117406). Clencyclohexerol-d10 is a β-agonist. Clencyclohexerol-d10 can be used as a growth promoter in animals .
|
-
-
- HY-N2593R
-
|
|
Reference Standards
Carnitine Palmitoyltransferase (CPT)
Reactive Oxygen Species (ROS)
Autophagy
Apoptosis
NF-κB
PI3K
Akt
MMP
Keap1-Nrf2
|
Inflammation/Immunology
Cancer
|
|
Isorhapontigenin (Standard) is the analytical standard of Isorhapontigenin (HY-N2593). This product is intended for research and analytical applications. Isorhapontigenin is an orally active dietary polyphenol. Isorhapontigenin acts as a potent antioxidant that reduces the production of reactive oxygen species (ROS). Isorhapontigenin promotes the binding of JUN to the AP-1 site on the SESN2 promoter, induces SESN2 transcription, triggers MAPK8-dependent JUN activation, and upregulates the expression of PPAR-α, PGC-1α and CPT-1A to facilitate fatty acid oxidation. Isorhapontigenin induces autophagy, apoptosis and preadipocyte differentiation; it inhibits tumor growth, cell invasion, NF-κB transcriptional activity, the PI3K/Akt signaling pathway, STAT1 phosphorylation and MMP-2 expression. Isorhapontigenin alleviates oxidative stress, inflammatory cytokine release and triglyceride accumulation; it increases intracellular ATP levels and promotes Nrf2 nuclear translocation. Isorhapontigenin improves insulin sensitivity in adipose tissue and glucose tolerance, and reduces postprandial blood glucose, insulin and free fatty acid levels. Isorhapontigenin is applicable to research on bladder cancer, liver injury, chronic obstructive pulmonary disease, acute lung injury and type 2 diabetes.
|
-
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- HY-180638
-
-
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- HY-N14751
-
|
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Others
|
Others
|
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Pteridic acid B is a plant growth promoter. Pteridic acid B has Auxin-like plant growth hormone activity, and 1 nM can promote the growth of legumes and other plant roots .
|
-
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- HY-N6709S1
-
|
α-Zearalanol-13C18
|
Isotope-Labeled Compounds
|
Endocrinology
|
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Zeranol- 13C18 (α-Zearalanol- 13C18) is the 13C-labeled Zeranol. Zeranol, a metabolite of the mycoestrogen zearalenone, is an estrogen receptor agonist. Zeranol is used as a growth promoter of livestock due to its strong estrogenic activity .
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- HY-24366
-
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Bacterial
DNA/RNA Synthesis
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Infection
|
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Quindoxin is an antibacterial and growth promoter, commonly used in the livestock industry. Quindoxin exhibits clear dose-dependent mutagenic activity against Salmonella typhimurium TA98 and TA100 strains. Quindoxin can cause DNA damage and has potential genotoxicity and carcinogenic risks .
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-
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- HY-N6709S2
-
|
α-Zearalanol-d5-1
|
Isotope-Labeled Compounds
Estrogen Receptor/ERR
|
Endocrinology
|
|
Zeranol-d5-1 (α-Zearalanol-d5-1) is the deuterium labeled Zeranol (HY-N6709). Zeranol, a metabolite of the mycoestrogen zearalenone, is an estrogen receptor agonist. Zeranol is used as a growth promoter of livestock due to its strong estrogenic activity .
|
-
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- HY-N19220
-
|
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Bacterial
Endogenous Metabolite
Antibiotic
|
Infection
Cancer
|
|
Radiclonic acid acts as an antibacterial agent, anticancer agent, and root growth promoter. Radiclonic acid is isolable from fungi of the genus Penicillium. Radiclonic acid exhibits antibacterial activity against MRSA with a MIC of 3.13 μg/mL. Radiclonic acid shows anticancer activity against esophageal cancer, bladder cancer, and liver cancer. Radiclonic acid promotes root growth in Chinese cabbage seedlings. Radiclonic acid is inactive against pancreatic cancer and cervical cancer. Radiclonic acid can be used in research related to Staphylococcus aureus infection, bladder cancer, esophageal cancer, and liver cancer .
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-
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- HY-120825
-
|
|
Apoptosis
DNA/RNA Synthesis
Reactive Oxygen Species (ROS)
Keap1-Nrf2
|
Cancer
|
|
QD 232 is a quinazolinedione-based ROS inducer and an apoptosis inducer with cytotoxicity and redox regulatory activity. QD 232 promotes ROS accumulation, activates the NRF2-mediated oxidative stress response and unfolded protein response pathways, and upregulates downstream antioxidant and stress response genes. QD 232 inhibits mtDNA transcription driven by HSP2 and LSP promoters, and impairs mitochondrial oxidative phosphorylation function. QD 232 induces apoptosis of pancreatic ductal adenocarcinoma cells and exerts cytotoxicity against gemcitabine (HY-17026)-resistant pancreatic ductal adenocarcinoma cells. QD 232 delays tumor growth in a mouse pancreatic cancer xenograft model .
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-
-
- HY-167262
-
|
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RAR/RXR
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Metabolic Disease
Cancer
|
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AGN-191659 is an orally active RAR/RXR agonist with EC50 values of 11 nM, 23 nM, and 37 nM for RXRα, RARβ, and RARγ, respectively. AGN-191659 activates RXRα, RARβ and RARγ to induce gene transcription. AGN-191659 induces tissue transglutaminase activity, inhibits ornithine decarboxylase activity induced by tumor promoters, and suppresses chondrogenesis. AGN-191659 reverses basic fibroblast growth factor-induced endothelial cell proliferation. AGN-191659 induces hypertriglyceridemia in rat models. AGN-191659 inhibits total heparin-releasable lipase activity. AGN-191659 can be used in research related to promyelocytic leukemia and hypertriglyceridemia .
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- HY-135146G
-
|
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DNA Methyltransferase
Apoptosis
|
Cancer
|
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GSK-3484862 GMP is GSK-3484862 (HY-135146) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. GSK-3484862 is a highly potent non-covalent inhibitor and demethylating agent of DNMT1. GSK-3484862 induces genome-wide DNA demethylation, including the regulatory elements of DNMT3B and the promoter region of TERT, and significantly inhibits cell viability, growth, proliferation and self-renewal. GSK-3484862 blocks the transformation of young AT2 cells, induces apoptosis, and generates transcriptomic features similar to those of senescent cells. GSK-3484862 is widely used in studies related to lung cancer, oral squamous cell carcinoma and lung adenocarcinoma .
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- HY-135146G
-
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Fluorescent Dyes
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GSK-3484862 GMP is GSK-3484862 (HY-135146) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. GSK-3484862 is a highly potent non-covalent inhibitor and demethylating agent of DNMT1. GSK-3484862 induces genome-wide DNA demethylation, including the regulatory elements of DNMT3B and the promoter region of TERT, and significantly inhibits cell viability, growth, proliferation and self-renewal. GSK-3484862 blocks the transformation of young AT2 cells, induces apoptosis, and generates transcriptomic features similar to those of senescent cells. GSK-3484862 is widely used in studies related to lung cancer, oral squamous cell carcinoma and lung adenocarcinoma .
|
-
- HY-W116336D
-
|
|
Biochemical Assay Reagents
|
|
Zinc oxide, <100 nm particle size is a nitrate reductase modulator and growth promoter with plant stress resistance activity and oral toxicity. Zinc oxide, <100 nm particle size acts as a nutrient source for maize plants. By enhancing nitrate reductase activity and reducing free proline levels, it significantly improves plant height, root length and dry matter weight of maize, and its growth-promoting effect is comparable to that of traditional zinc sulfate fertilizer. Zinc oxide, <100 nm particle size induces anemia-related and persistent tissue inflammatory damage, leading to obvious histopathological adverse reactions in the stomach, pancreas, eyes and prostate of rats. Zinc oxide, <100 nm particle size acts as a non-toxic antibacterial agent and selective cytotoxin against multiple bacteria, fungi and spores .
|
-
- HY-150287A
-
|
ITS-X
|
Biochemical Assay Reagents
|
|
Insulin-Transferrin-Selenium-Ethanolamine (ITS-X) is a cell culture supplement as well as a cell growth and adhesion promoter. Insulin-Transferrin-Selenium-Ethanolamine supports adhesion, pseudopodium formation, pseudopodium elongation and proliferation of adherent cancer cells in serum-free culture systems .
|
-
- HY-135146G
-
|
|
Biochemical Assay Reagents
|
|
GSK-3484862 GMP is GSK-3484862 (HY-135146) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. GSK-3484862 is a highly potent non-covalent inhibitor and demethylating agent of DNMT1. GSK-3484862 induces genome-wide DNA demethylation, including the regulatory elements of DNMT3B and the promoter region of TERT, and significantly inhibits cell viability, growth, proliferation and self-renewal. GSK-3484862 blocks the transformation of young AT2 cells, induces apoptosis, and generates transcriptomic features similar to those of senescent cells. GSK-3484862 is widely used in studies related to lung cancer, oral squamous cell carcinoma and lung adenocarcinoma .
|
| Cat. No. |
상품명 |
Target |
Research Area |
Image |
-
- HY-P99911
-
|
MEDI-6383
|
Orexin Receptor (OX Receptor)
|
Inflammation/Immunology
Cancer
|
|
Efizonerimod alfa (MEDI-6383) is a recombinant human OX40L IgG4P Fc fusion protein that assembles into a hexameric structure and exerts potent agonist activity upon binding to OX40. The activity of Efizonerimod alfa is enhanced by Fcγ receptor-mediated aggregation. Efizonerimod alfa binds to OX40 on the surface of activated T cells, induces NF-κB promoter activity in OX40-expressing T cells, and triggers the production of Th1-type cytokines, T cell proliferation, and resistance to regulatory T cell (Treg)-mediated suppression. Efizonerimod alfa enhances the cytolytic activity of tumor-reactive T cells and slows tumor growth in immunodeficient mice. Efizonerimod alfa induces the proliferation of CD4, CD8, and B cells in the peripheral blood of healthy non-human primates. Efizonerimod alfa can be used in the research of advanced solid malignancies and melanoma .
|
-
(5)
| Cat. No. |
상품명 |
Category |
Target |
Chemical Structure |
-
- HY-N2593
-
|
|
Structural Classification
Stilbenes
Classification of Application Fields
Gnetum cleistostachyum C. Y. Cheng
Phenols
Polyphenols
Gnetaceae
Plants
Inflammation/Immunology
Disease Research Fields
Source Classification
|
Carnitine Palmitoyltransferase (CPT)
Reactive Oxygen Species (ROS)
Autophagy
Apoptosis
NF-κB
PI3K
Akt
MMP
Keap1-Nrf2
|
|
Isorhapontigenin is an orally active dietary polyphenol. Isorhapontigenin acts as a potent antioxidant that reduces the production of reactive oxygen species (ROS). Isorhapontigenin promotes the binding of JUN to the AP-1 site on the SESN2 promoter, induces SESN2 transcription, triggers MAPK8-dependent JUN activation, and upregulates the expression of PPAR-α, PGC-1α and CPT-1A to facilitate fatty acid oxidation. Isorhapontigenin induces autophagy, apoptosis and preadipocyte differentiation; it inhibits tumor growth, cell invasion, NF-κB transcriptional activity, the PI3K/Akt signaling pathway, STAT1 phosphorylation and MMP-2 expression. Isorhapontigenin alleviates oxidative stress, inflammatory cytokine release and triglyceride accumulation; it increases intracellular ATP levels and promotes Nrf2 nuclear translocation. Isorhapontigenin improves insulin sensitivity in adipose tissue and glucose tolerance, and reduces postprandial blood glucose, insulin and free fatty acid levels. Isorhapontigenin is applicable to research on bladder cancer, liver injury, chronic obstructive pulmonary disease, acute lung injury and type 2 diabetes .
|
-
-
- HY-122485
-
-
-
- HY-137129
-
-
-
- HY-N10341
-
|
|
Flavonoids
Flavones
Tanacetum microphyllum DC.
Plants
Compositae
Source Classification
|
IFNAR
ROCK
|
|
Centaureidin is an orally active IFN-promoter that can be isolated from Bidens pilosa with an EC50 of 0.9 μg/mL. Centaureidin activates the Rho signal pathway, leading to actin and tubulin disassembly, and resulting in dendrite retraction and stress fiber formation in melanocytes. Centaureidin shows high tumor cell growth inhibitory activities. Centaureidin significantly inhibits paw edema in mice [1][2][3][4][5].
|
-
-
- HY-N14742
-
-
-
- HY-N15532
-
-
-
- HY-N2593R
-
|
|
Structural Classification
Stilbenes
Gnetum cleistostachyum C. Y. Cheng
Phenols
Polyphenols
Gnetaceae
Plants
Source Classification
|
Reference Standards
Carnitine Palmitoyltransferase (CPT)
Reactive Oxygen Species (ROS)
Autophagy
Apoptosis
NF-κB
PI3K
Akt
MMP
Keap1-Nrf2
|
|
Isorhapontigenin (Standard) is the analytical standard of Isorhapontigenin (HY-N2593). This product is intended for research and analytical applications. Isorhapontigenin is an orally active dietary polyphenol. Isorhapontigenin acts as a potent antioxidant that reduces the production of reactive oxygen species (ROS). Isorhapontigenin promotes the binding of JUN to the AP-1 site on the SESN2 promoter, induces SESN2 transcription, triggers MAPK8-dependent JUN activation, and upregulates the expression of PPAR-α, PGC-1α and CPT-1A to facilitate fatty acid oxidation. Isorhapontigenin induces autophagy, apoptosis and preadipocyte differentiation; it inhibits tumor growth, cell invasion, NF-κB transcriptional activity, the PI3K/Akt signaling pathway, STAT1 phosphorylation and MMP-2 expression. Isorhapontigenin alleviates oxidative stress, inflammatory cytokine release and triglyceride accumulation; it increases intracellular ATP levels and promotes Nrf2 nuclear translocation. Isorhapontigenin improves insulin sensitivity in adipose tissue and glucose tolerance, and reduces postprandial blood glucose, insulin and free fatty acid levels. Isorhapontigenin is applicable to research on bladder cancer, liver injury, chronic obstructive pulmonary disease, acute lung injury and type 2 diabetes.
|
-
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- HY-180638
-
-
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- HY-N14751
-
-
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- HY-N19220
-
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Structural Classification
Microorganisms
Lipid
Source Classification
|
Bacterial
Endogenous Metabolite
Antibiotic
|
|
Radiclonic acid acts as an antibacterial agent, anticancer agent, and root growth promoter. Radiclonic acid is isolable from fungi of the genus Penicillium. Radiclonic acid exhibits antibacterial activity against MRSA with a MIC of 3.13 μg/mL. Radiclonic acid shows anticancer activity against esophageal cancer, bladder cancer, and liver cancer. Radiclonic acid promotes root growth in Chinese cabbage seedlings. Radiclonic acid is inactive against pancreatic cancer and cervical cancer. Radiclonic acid can be used in research related to Staphylococcus aureus infection, bladder cancer, esophageal cancer, and liver cancer .
|
-
| Cat. No. |
상품명 |
Chemical Structure |
-
- HY-W777284
-
|
|
|
Zeranol-d5 (mixture of diastereomers) is the deuterium labeled Zeranol (HY-N6709). Zeranol, a metabolite of the mycoestrogen zearalenone, is an estrogen receptor agonist. Zeranol is used as a growth promoter of livestock due to its strong estrogenic activity .
|
-
-
- HY-W742012
-
|
|
|
Clencyclohexerol-d10 is the deuterium-labeled Clencyclohexerol (HY-117406). Clencyclohexerol-d10 is a β-agonist. Clencyclohexerol-d10 can be used as a growth promoter in animals .
|
-
-
- HY-N6709S1
-
|
|
|
Zeranol- 13C18 (α-Zearalanol- 13C18) is the 13C-labeled Zeranol. Zeranol, a metabolite of the mycoestrogen zearalenone, is an estrogen receptor agonist. Zeranol is used as a growth promoter of livestock due to its strong estrogenic activity .
|
-
-
- HY-N6709S2
-
|
|
|
Zeranol-d5-1 (α-Zearalanol-d5-1) is the deuterium labeled Zeranol (HY-N6709). Zeranol, a metabolite of the mycoestrogen zearalenone, is an estrogen receptor agonist. Zeranol is used as a growth promoter of livestock due to its strong estrogenic activity .
|
-
| Cat. No. |
상품명 |
|
Classification |
-
- HY-177375
-
|
|
|
saRNAs
|
|
dsP53-285 saRNA is a small activating RNA (saRNA) that readily activates wild-type p53 expression by targeting its promoter. dsP53-285 saRNA suppresses bladder cancer cells growth and metastasis .
|
| Cat. No. |
상품명 |
Target |
연구분야 |
Chemical Structure |
-
- HY-135146G
-
|
|
DNA Methyltransferase
Apoptosis
|
Cancer
|
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GSK-3484862 GMP is GSK-3484862 (HY-135146) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. GSK-3484862 is a highly potent non-covalent inhibitor and demethylating agent of DNMT1. GSK-3484862 induces genome-wide DNA demethylation, including the regulatory elements of DNMT3B and the promoter region of TERT, and significantly inhibits cell viability, growth, proliferation and self-renewal. GSK-3484862 blocks the transformation of young AT2 cells, induces apoptosis, and generates transcriptomic features similar to those of senescent cells. GSK-3484862 is widely used in studies related to lung cancer, oral squamous cell carcinoma and lung adenocarcinoma .
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