2. Anti-infection Metabolic Enzyme/Protease
  3. Bacterial Endogenous Metabolite Antibiotic
  4. Radiclonic acid

Radiclonic acid acts as an antibacterial agent, anticancer agent, and root growth promoter. Radiclonic acid is isolable from fungi of the genus Penicillium. Radiclonic acid exhibits antibacterial activity against MRSA with a MIC of 3.13 μg/mL. Radiclonic acid shows anticancer activity against esophageal cancer, bladder cancer, and liver cancer. Radiclonic acid promotes root growth in Chinese cabbage seedlings. Radiclonic acid is inactive against pancreatic cancer and cervical cancer. Radiclonic acid can be used in research related to Staphylococcus aureus infection, bladder cancer, esophageal cancer, and liver cancer.

For research use only. We do not sell to patients.

Radiclonic acid

Radiclonic acid Chemical Structure

CAS No. : 49620-14-6

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Radiclonic acid Related Antibodies

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Description

Radiclonic acid acts as an antibacterial agent, anticancer agent, and root growth promoter. Radiclonic acid is isolable from fungi of the genus Penicillium. Radiclonic acid exhibits antibacterial activity against MRSA with a MIC of 3.13 μg/mL. Radiclonic acid shows anticancer activity against esophageal cancer, bladder cancer, and liver cancer. Radiclonic acid promotes root growth in Chinese cabbage seedlings. Radiclonic acid is inactive against pancreatic cancer and cervical cancer. Radiclonic acid can be used in research related to Staphylococcus aureus infection, bladder cancer, esophageal cancer, and liver cancer[1][2][3].

IC50 & Target[1]

Fungal Metabolite

 

In Vitro

Radiclonic acid (3.13 μg/mL) inhibits the growth of MRSA with an MIC of 3.13 μg/mL[2].
Radiclonic acid (0-20 μM; 48 h) potently inhibits ECA109 (IC50 = 7.70 μM), BIU-87 (IC50 = 12.47 μM), and BEL-7402 (IC50 = 13.75 μM) human cancer cell lines, while showing no significant activity against PANC-1 and Hela-S3 cell lines[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Radiclonic acid Related Antibodies

Cell Cytotoxicity Assay[3]

Cell Line: BIU-87, ECA109, BEL-7402, PANC-1, Hela-S3
Concentration: 0-20 μM
Incubation Time: 48 h
Result: Showed inhibitory activity against ECA109, BIU-87, and BEL-7402 cell lines with IC50 values of 7.70, 12.47, and 13.75 μM, respectively.
Exhibited inhibition rates less than 50% against PANC-1 and Hela-S3 cell lines, with IC50 values greater than 20 μM.
Molecular Weight

396.57

Formula

C23H40O5
CAS No.
SMILES

C(=C/C(=C/[C@H](C[C@H](C[C@H](C[C@H](CC)C)C)CO)C)/C)(\C[C@@H](C(O)=O)C)/C(O)=O
Structure Classification
Initial Source

Talaromyces pinophilus AF-02
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Radiclonic acid Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Radiclonic acid49620-14-6BacterialEndogenous MetaboliteAntibioticmethicillin-resistant Staphylococcus aureusTalaromyces sp.Penicillium sp.esophageal cancer cellscervical cancer cellsECA109liver cancer cellspancreatic cancer cellsChinese cabbage seedlingsbladder cancer cellsInhibitorinhibitorinhibit

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