Radiclonic acid
Radiclonic acid acts as an Antibacterial agent, anticancer agent, and root growth promoter. Radiclonic acid is isolable from fungi of the genus Penicillium. Radiclonic acid exhibits antibacterial activity against MRSA with a MIC of 3.13 μg/mL. Radiclonic acid shows anticancer activity against esophageal cancer, bladder cancer, and liver cancer. Radiclonic acid promotes root growth in Chinese cabbage seedlings. Radiclonic acid is inactive against pancreatic cancer and cervical cancer. Radiclonic acid can be used in research related to Staphylococcus aureus infection, bladder cancer, esophageal cancer, and liver cancer.
For research use only. We do not sell to patients.
- CAS No.: 49620-14-6
- Formula: C23H40O5
- Molecular Weight:396.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Fungal Metabolite |
Radiclonic acid (3.13 μg/mL) inhibits the growth of MRSA with an MIC of 3.13 μg/mL[2].
Radiclonic acid (0-20 μM; 48 h) potently inhibits ECA109 (IC50 = 7.70 μM), BIU-87 (IC50 = 12.47 μM), and BEL-7402 (IC50 = 13.75 μM) human cancer cell lines, while showing no significant activity against PANC-1 and Hela-S3 cell lines[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:BIU-87, ECA109, BEL-7402, PANC-1, Hela-S3
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Concentration:0-20 μM
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Incubation Time:48 h
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Result:Showed inhibitory activity against ECA109, BIU-87, and BEL-7402 cell lines with IC50 values of 7.70, 12.47, and 13.75 μM, respectively.
Exhibited inhibition rates less than 50% against PANC-1 and Hela-S3 cell lines, with IC50 values greater than 20 μM.
Chemical Information
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CAS No. 49620-14-6
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Molecular Weight 396.57
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Formula C23H40O5
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SMILES
C(=C/C(=C/[C@H](C[C@H](C[C@H](C[C@H](CC)C)C)CO)C)/C)(\C[C@@H](C(O)=O)C)/C(O)=O
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Structure Classification
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Initial Source
Talaromyces pinophilus AF-02
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[2]. Chu MJ, et al. Marine natural products with anti-MRSA activities: promising candidates for antibacterial drug discovery. Bioorg Chem. 2025 Dec;167:109242. [Content Brief]
[3]. Niu S, et al. Cytotoxic Polyketides Isolated from the Deep-Sea-Derived Fungus Penicillium chrysogenum MCCC 3A00292. Mar Drugs. 2019 Dec 5;17(12):686. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Radiclonic acid Related Classifications
HY-N19220 Related Classifications
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