49620-14-6
Chemical Structure
Radiclonic acid
- CAS No.: 49620-14-6
- Formula:C23H40O5
- Molecular Weight:396.57
IUPAC Name: (S,Z)-2-((4S,6S,8S,10S,E)-6-(hydroxymethyl)-2,4,8,10-tetramethyldodec-2-en-1-ylidene)-4-methylpentanedioic acid
InChIKey: NNPPLRJHBQPBAQ-FAKBHOIGSA-N
SMILES: C(=C/C(=C/[C@H](C[C@H](C[C@H](C[C@H](CC)C)C)CO)C)/C)(\C[C@@H](C(O)=O)C)/C(O)=O
Biological Activity: Radiclonic acid acts as an Antibacterial agent, anticancer agent, and root growth promoter. Radiclonic acid is isolable from fungi of the genus Penicillium. Radiclonic acid exhibits antibacterial activity against MRSA with a MIC of 3.13 μg/mL. Radiclonic acid shows anticancer activity against esophageal cancer, bladder cancer, and liver cancer. Radiclonic acid promotes root growth in Chinese cabbage seedlings. Radiclonic acid is inactive against pancreatic cancer and cervical cancer. Radiclonic acid can be used in research related to Staphylococcus aureus infection, bladder cancer, esophageal cancer, and liver cancer[1][2][3].
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Radiclonic acid | Radiclonic acid acts as an Antibacterial agent, anticancer agent, and root growth promoter. Radiclonic acid is isolable from fungi of the genus Penicillium. Radiclonic acid exhibits antibacterial activity against MRSA with a MIC of 3.13 μg/mL. Radiclonic acid shows anticancer activity against esophageal cancer, bladder cancer, and liver cancer. Radiclonic acid promotes root growth in Chinese cabbage seedlings. Radiclonic acid is inactive against pancreatic cancer and cervical cancer. Radiclonic acid can be used in research related to Staphylococcus aureus infection, bladder cancer, esophageal cancer, and liver cancer. | |||||||||||||||||||||
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- [1]. Sassa, et al. Isolation and identification of o-acetyl and 12-hydroxyradiclonic acids[J]. Agricultural and Biological Chemistry, 1975, 39(9): 1899-1900.
- [2]. Chu MJ, et al. Marine natural products with anti-MRSA activities: promising candidates for antibacterial drug discovery. Bioorg Chem. 2025 Dec;167:109242. [Content Brief]
- [3]. Niu S, et al. Cytotoxic Polyketides Isolated from the Deep-Sea-Derived Fungus Penicillium chrysogenum MCCC 3A00292. Mar Drugs. 2019 Dec 5;17(12):686. [Content Brief]
Keywords
